(n.) One who administers affairs; one who directs, manages, executes, or dispenses, whether in civil, judicial, political, or ecclesiastical affairs; a manager.
(n.) A man who manages or settles the estate of an intestate, or of a testator when there is no competent executor; one to whom the right of administration has been committed by competent authority.
Example Sentences:
(1) We conclude that chronic emphysema produced in dogs by aerosol administration of papain results in elevated pulmonary artery pressure, which is characterized pathologically by medial hypertrophy of small pulmonary arteries.
(2) Intravesical BCG is clearly superior to oral BCG, and controlled studies have demonstrated that percutaneous administration is not necessary.
(3) Morphological alterations in the lungs of pheasants after prolonged high-dosage administration of bleomycin sulfate were studied by light and electron microscopy.
(4) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(5) administration of the potent short-acting opioid, fentanyl, elicited inhibition of rhythmic spontaneous reflex increases in vesical pressure (VP) evoked by urinary bladder distension.
(6) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
(7) In a climate in which medical staffs are being sued as a result of their decisions in peer review activities, hospitals' administrative and medical staffs are becoming more cautious in their approach to medical staff privileging.
(8) Hepatic lymph flow increased only after ethacrynic acid and mannitol administration.
(9) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
(10) The statistical T value calculated for the LP-TAE group showed that the administration of LP, the tumor size, intrahepatic metastasis, portal vein infiltration, and serum total bilirubin and alpha-fetoprotein levels significantly (P < 0.01) affected the patients' survival.
(11) The program met with continued support and enthusiasm from nurse administrators, nursing unit managers, clinical educators, ward staff and course participants.
(12) We evaluated the circadian pattern of gastric acidity by prolonged intraluminal pHmetry in 15 "responder" and 10 "nonresponder" duodenal ulcer patients after nocturnal administration of placebo, ranitidine, and famotidine.
(13) Oral administration in domestic cats causes malignant hepatomas and tumors of the esophagus and kidney.
(14) Determination of plasma luteinizing hormone (LH) levels in the peripubertal female rats revealed that plasma LH was increased transiently immediately after NPY administration.
(15) The effects of in vivo administration of native prostaglandin E2 (PGE) on the cycling status of the granulocyte-monocyte progenitor cell (CFU-GM) were examined in a mouse model.
(16) However, there was no consistent protocol for the method or duration of drug administration.
(17) The secretion of GH as measured by increased plasma level, in response to oral administration of 500 mg L-dopa or 30 min-infusion of arginine, was not modified by prior intravenous administration of 200 micrograms GH-releasing hormone (GHRH).
(18) Exogenous administration of estrogen alone or combined with progesterone have been associated with increased plasma cortisol levels.
(19) The simultaneous administration of the yellow fever vaccine did not influence the titre of agglutinins induced by the classic cholera vaccine.
(20) "This was very strategic and it was in line of the ideology of the Bush administration which has been to put in place a free market and conservative agenda."
Necessitate
Definition:
(v. t.) To make necessary or indispensable; to render unaviolable.
(v. t.) To reduce to the necessity of; to force; to compel.
Example Sentences:
(1) Rapid overgrowth of all cultures with the E. coli necessitated the use of selective media containing antimicrobial agents to which the E. coli was sensitive.
(2) There were two postoperative stomal prolapses, one of which necessitated reoperation.
(3) Since the early 1960's nasotracheal tubes have been used for neonates with primary respiratory diseases which necessitated positive pressure ventilation.
(4) The presence of vital and sensitive organs such as the spinal cord, heart, and lungs makes curative radiotherapy of non-small cell lung cancer difficult to implement and necessitates use of oblique portals.
(5) An epidemiological survey carried out in 460 public and private institutions chosen at random country-wide in France made it possible to study injuries whose treatment had necessitated an anaesthetic.
(6) Judging from available clinical studies, surgical fusion operations may be useful in properly selected patients with spondylolisthesis or in situations for which the surgical approach has necessitated destabilization by laminectomy and facetectomy.
(7) Side effects of carbenoxolone therapy were observed, but they did not necessitate withdrawal of the drug and were readily controlled in every instance.
(8) The presence of severe pulmonary disease is the critical factor that might necessitate a staged repair.
(9) The influence of preanalytical factors such as food intake, posture, use of tourniquet and freezing and storing samples is great and necessitates standardisation of specimen collection.
(10) In the others, serum PTH remained elevated and subsequent symptomatic hypercalcaemia necessitated parathyroidectomy.
(11) Shaping and fine working of restorations necessitated by cervical lesions, abrasions at the necks of teeth, or root surface caries can often be arduous to complete.
(12) The surgical removal of branchiomeric paragangliomas necessitates preparation of a small saphenous vein bypass in case it is not possible to avoid sacrificing the internal carotid artery.
(13) Two patients had mild pancreatitis, which necessitated endoscopic sphincterotomy in one.
(14) Reoperation was more frequent after valve replacement with bioprostheses (6.7% per patient year) than after valvuloplasty (4.3% per patient year) and after mechanical valve replacement (1.5% per patient year; P less than 0.02), and was necessitated mainly by residual or recurrent valve dysfunction after valvuloplasty, bland or infected periprosthetic leaks in mechanical valves and degradation of bioprostheses.
(15) Estimation of pairwise connectivity is the most common method of determining the neural 'network' but usually necessitates the production of numerous histograms for each pair considered.
(16) These lesions might necessitate further surgical treatment as possibly total joint prosthesis.
(17) The diagnostic criteria of potentially fatal asthma included at least one of the following four potentially fatal asthma events: 1) mechanical ventilation for respiratory arrest or failure, 2) acute respiratory acidosis that did not necessitate mechanical ventilation, 3) two episodes of acute pneumomediastinum or pneumothorax associated with status asthmaticus, 4) two or more hospitalizations for status asthmaticus in spite of long term oral corticosteroids.
(18) The recent discovery of the existence of a second mouse TSP gene necessitates careful examination of the discrete biochemical and functional properties associated with each molecule.
(19) Thirteen cases were considered medical treatment failures, and 11 necessitated therapeutic surgery.
(20) The classic scoliosis was resistant to brace treatment; bracing failed in 70% of patients, necessitating spinal fusion.