(v. t.) To bring forward; to move towards the van or front; to make to go on.
(v. t.) To raise; to elevate.
(v. t.) To raise to a higher rank; to promote.
(v. t.) To accelerate the growth or progress; to further; to forward; to help on; to aid; to heighten; as, to advance the ripening of fruit; to advance one's interests.
(v. t.) To bring to view or notice; to offer or propose; to show; as, to advance an argument.
(v. t.) To make earlier, as an event or date; to hasten.
(v. t.) To furnish, as money or other value, before it becomes due, or in aid of an enterprise; to supply beforehand; as, a merchant advances money on a contract or on goods consigned to him.
(v. t.) To raise to a higher point; to enhance; to raise in rate; as, to advance the price of goods.
(v. t.) To extol; to laud.
(v. i.) To move or go forward; to proceed; as, he advanced to greet me.
(v. i.) To increase or make progress in any respect; as, to advance in knowledge, in stature, in years, in price.
(v. i.) To rise in rank, office, or consequence; to be preferred or promoted.
(v.) The act of advancing or moving forward or upward; progress.
(v.) Improvement or progression, physically, mentally, morally, or socially; as, an advance in health, knowledge, or religion; an advance in rank or office.
(v.) An addition to the price; rise in price or value; as, an advance on the prime cost of goods.
(v.) The first step towards the attainment of a result; approach made to gain favor, to form an acquaintance, to adjust a difference, etc.; an overture; a tender; an offer; -- usually in the plural.
(v.) A furnishing of something before an equivalent is received (as money or goods), towards a capital or stock, or on loan; payment beforehand; the money or goods thus furnished; money or value supplied beforehand.
(a.) Before in place, or beforehand in time; -- used for advanced; as, an advance guard, or that before the main guard or body of an army; advance payment, or that made before it is due; advance proofs, advance sheets, pages of a forthcoming volume, received in advance of the time of publication.
Example Sentences:
(1) This selective review emphasizes advances in neurochemistry which provide a context for current and future research on neurological and psychiatric disorders encountered in clinical practice.
(2) Increased plasmin activity was associated with advancing stage of lactation and older cows after appropriate adjustments were made for the effects of milk yield and SCC.
(3) These results suggest that the pelvic floor is affected by progressive denervation but descent during straining tends to decrease with advancing age.
(4) An association of cyclophosphamide, fluorouracil and methotrexate already employed with success against solid tumours in other sites was used in the treatment of 62 patients with advanced tumours of the head and neck.
(5) When TSLP was pretreated with TF5 in vitro, the most restorative effects on the decreased MLR were found in hyperplastic stage and the effects were becoming less with the advance of tumor developments.
(6) Finally the advanced automation of the equipment allowed weekly the evaluation of catecholamines and the whole range of their known metabolites in 36 urine samples.
(7) Since the advance and return of sperm inside the tubes could facilitate the interaction of sperm with secretions participating in its maturation, the persistent infertility after vasectomy could be related to the contractile alteration that follows the excessive tubal distention.
(8) Over the past decade the use of monoclonal antibodies has greatly advanced our knowledge of the biological properties and heterogeneity that exist within human tumours, and in particular in lung cancer.
(9) The automatic half of both the motor which advances the trepan as well as the second motor which rotates the trepan is triggered by the sudden change in electrical resistance between the trepan and the patient's internal body fluid, at the final stage of penetration.
(10) Under a revised deal most people are now being vetted on time, but charges for the service have had to rise from £12 and free vetting for volunteers, to £28 for a standard disclosure and £33 for an advanced disclosure.
(11) Histological and electron-microscopic study of the lungs of 15 patients who had been treated with bleomycin for advanced squamous cell carcinoma demonstrated marked histological changes in nine.
(12) With better understanding of metabolic and compositional requirements, great advances have been made in the area of total parenteral nutrition.
(13) Meanwhile Ed Miliband, the Labour leader, waiting anxiously for news of the scale of the Labour advance in his first nationwide electoral test, will urge the electorate not to be duped by the promise of a coalition mark 2, predicting sham concessions by the Conservatives .
(14) 16 tube (usually a Baker tube) was inserted by gastrostomy and advanced distally into the colon.
(15) Of his number, 266 patients were in the advance stage of their disease while another 42 still had localized cancers.
(16) N-Acetyl-beta-D-glucosaminidase (GAD) activities did not change significantly duringlate fetal, neonatal or young adult stages but increased significantly with advancing age.
(17) Serial antepartum platelet alloantibody quantitation by an enzyme-linked immunoabsorbent assay revealed rising antibody titers during advancing gestation.
(18) Most of the progressive cases were alcoholic, and some showed progression to advanced pancreatitis within 4 years.
(19) Expansion of the cell sheet following attachment, and the fusion of epiblasts advancing toward each other, does not require the presence of mineralocorticoid.
(20) One hundred and sixteen patients with advanced and metastatic adenocarcinoma of the pancreas were randomized to treatment with combined Streptozotocin and 5-fluorouracil or combined Streptozotocin and cyclophosphamide.
Maximize
Definition:
(v. t.) To increase to the highest degree.
Example Sentences:
(1) We maximize an objective function that includes both total production rate and product concentration.
(2) Further, the maximal increase in force of contraction was measured using papillary muscle strips from some of these patients.
(3) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(4) Maximal yields of lipid and aflatoxin were obtained with 30% glucose, whereas mold growth, expressed as dry weight, was maximal when the medium contained 10% glucose.
(5) Maximal aberration yields were observed for 2,4-diaminotoluene, 2,6-diaminotoluene and cytosine beta-D-arabinofuranoside from 17 to 21 h, eugenol from 15 to 21 h, cadmium sulfate from 15 to 24 h and 2-aminobiphenyl, from 17 to 24 h. For adriamycin at 1 microM, the % aberrant cells remained elevated throughout the period from 9 to 29 h, while small increases at 0.1 microM ADR were found only at 13 and at 25 h. For most chemicals the maximal aberration yield occurred at a different time for each concentration tested.
(6) Maximal covalent binding of [4,5-14C]ronidazole to DNA also required four-electron reduction, consistent with previous studies of the covalent binding of this agent to immobilized sulfhydryl groups [Kedderis et al.
(7) The Cao-dependent Na+ efflux was half-maximally activated by [Ca2+]o = 2.0 mM in LiSW and 7.2 mM in Tris-SW; at saturating [Ca2+]o, [Ca2+]i, and [Na+]i the maximal (calculated) Cao-dependent Na+ efflux was approximately 75 pmol#cm2.s.
(8) Short incubations with heparin (5 min) caused a release of the enzyme into the media, while longer incubations caused a 2-8-fold increase in net lipoprotein lipase secretion which was maximal after 2-16 h depending on cell type, and persisted for 24 h. The effect of heparin was dose-dependent and specific (it was not duplicated by other glycosaminoglycans).
(9) Combining maximally effective concentrations of each of these stimulating agents produces an additive increase in both the level of 32P incorporation into tyrosine hydroxylase and the degree of activation of the enzyme.
(10) Using serial section electron microscopic reconstructions as a reference, we have chosen as our standard procedure a method that maximizes both the preservation of the cytoskeleton and the proportion of cells staining, while minimizing the degree of nonspecific staining.
(11) Basal and maximally insulin-stimulated rates of 3-O-methylglucose transport in adipocytes from obese and obese NIDDM subjects were reduced to 50% of the values in cells from normal subjects (P less than 0.05).
(12) We assumed that the sensory messages received at a given level are transformed by a stochastic process, called Alopex, in a way which maximizes responses in central feature analyzers.
(13) Both gp175 and gp250 showed the greatest increase in fucosylation at 10(-5) M, which was also the dose at which RA induced laminin maximally, while the fucosylation of gp400 was greatest at 10(-8) M RA and declined at higher concentrations.
(14) However, those studies used partial maximal expiratory flow volume (PMEFV) curves to assess lung function.
(15) Hyperosmolar buffer slightly increased the sensitivity and maximal response to methacholine as well as the cholinergic twitch to electric field stimulation.
(16) Cytosolic-to-mitochondrial ratios from maximal initial rates after correction for mitochondrial breakage were increased above controls in diabetic hearts for nucleoside diphosphokinase and aspartate aminotransferase.
(17) The drug-picrate chromophores maximally absorb within the first minute of reaction (21 s for phenacemide, 45 s for cephalothin), after which the absorbances decrease.
(18) Glucagon can raise intracellular cyclic AMP about 30-fold; a half-maximal effect is obtained with 1.5 nM hormone.
(19) Keeping calcium concentration constant in the medium (0.36 microM), ornithine transport was maximal at 5.0 microM L-arginine and decreased at higher concentrations of arginine.
(20) Immediately prior to and at maximal workloads, carbon monoxide shifted into extravascular spaces and returned to the vascular space within five minutes after exercise stopped.