(1) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(2) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(3) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(4) Because cystine in medium was converted rapidly to cysteine and cysteinyl-NAC in the presence of NAC and given that cysteine has a higher affinity for uptake by EC than cystine, we conclude that the enhanced uptake of radioactivity was in the form of cysteine and at least part of the stimulatory effect of NAC on EC glutathione was due to a formation of cysteine by a mixed disulfide reaction of NAC with cystine similar to that previously reported for Chinese hamster ovarian cells (R. D. Issels et al.
(5) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(6) This theory was confirmed by product analysis and by measuring the affinity of the substrate for the enzyme by its inhibition of p-nitrophenyl glucoside hydrolysis.
(7) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(8) ASF-II was purified to apparent homogeneity by using concanavalin A-agarose affinity chromatography, DEAE-cellulose chromatography, alumina gel adsorption, and isoelectric focussing techniques.
(9) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(10) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(11) The penicillin-resistant Enterococcus hirae R40 has a typical profile of membrane-bound penicillin-binding proteins (PBPs) except that the 71 kDa PBP5 of low penicillin affinity represents about 50% of all the PBPs present.
(12) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(13) Only estrogenic hormones are bound with high affinity.
(14) These results indicate that both the renal brush-border and basolateral membranes possess the Na(+)-dependent dicarboxylate transport system with very similar properties but with different substrate affinity and transport capacity.
(15) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(16) Neurotensin (NT) is an endogenous brain tridecapeptide for which high affinity binding sites exist in the central nervous system.
(17) In lactate medium the capacity of each AIB carrier is unchanged but its affinity is reduced to one-third.
(18) The telencephalon of teleost fish shows high affinity uptake for D-[3H]aspartate, intermediate levels of GABAergic markers and low levels of cholinergic enzymes.
(19) In all immunized rabbits the antisera obtained with the 7 alpha-derivative had a higher affinity and a narrower specificity than the antiserum obtained with the 7 beta-derivative.
(20) The binding parameters indicate that the principal activating effect of UMP is not simply to increase the affinity of the enzyme for glucose.
Marriage
Definition:
(v. t.) The act of marrying, or the state of being married; legal union of a man and a woman for life, as husband and wife; wedlock; matrimony.
(v. t.) The marriage vow or contract.
(v. t.) A feast made on the occasion of a marriage.
(v. t.) Any intimate or close union.
Example Sentences:
(1) An intact post-injury marriage was associated with improvement in education.
(2) Johnson and Campion are optimistic that marriage equality will win out, and soon.
(3) During the couple's 30-year marriage she had twice reported him to the police for grabbing her by the throat, before they divorced in 2005.
(4) Movies such as Concussion , about the dissatisfactions of a bourgeois lesbian marriage, are already starting to ask these questions.
(5) Yet, polls have Maryland voters approving same-sex marriage by 14 to 20 points.
(6) He has also been a vocal opponent of gay marriage, appearing on the Today programme in the run-up to the same-sex marriage bill to warn that it would "cause confusion" – and asking in a Spectator column, after it was passed, "if the law will eventually be changed to allow one to marry one's dog".
(7) A federal judge struck down Utah's same-sex marriage ban Friday in a decision that brings a nationwide shift toward allowing gay marriage to a conservative state where the Mormon church has long been against it.
(8) "Today a federal district court put up a roadblock on a path constructed by 21 federal court rulings over the last year – a path that inevitably leads to nationwide marriage equality," said Sarah Warbelow, legal director for the Human Rights Campaign.
(9) It wasn't the best marriage – Jackie left me in 1962 when my first son, Paul, was 18 months old.
(10) The author discusses marriages in which a basically insecure husband plays a god-like role and his wife, who initially worshipped him, matures and finds her situation depressing and degrading.
(11) But she has struggled – quite awkwardly – to articulate her evolution on same-sex marriage, and has left environmental activists wondering what her exact energy policy is.
(12) Pope Francis’s no-longer-secret meeting in Washington DC with anti-gay activist Kim Davis, the controversial Kentucky county clerk who was briefly jailed over her refusal to issue same-sex marriage licenses in compliance with state law, leaves LGBT people with no illusions about the Pope’s stance on equal rights for us, despite his call for inclusiveness.
(13) America's same-sex couples, and the politicians who have barred gay marriage in 30 states, are looking to the supreme court to hand down a definitive judgment on where the constitution stands on an issue its framers are unlikely to have imagined would ever be considered.
(14) I thought she had been put out of her misery by marriage but now she is a widow.
(15) If we were to have a plebiscite before the end of the year, and you were to reverse-engineer that, it would make interesting speculation about the timing of an election.” Abetz said in January he would need to see whether a plebiscite was “above board or whether the question is stacked” before deciding to heed any result in favour of marriage equality.
(16) A case of fragile-X syndrome (the Martin-Bell syndrome) in two male half-sibs from different marriages of their mother was described.
(17) The ACT’s opposition leader, Jeremy Hanson, said during Tuesday’s debate that the uncertainty surrounding the new same-sex marriage regime created significant problems for couples, and he suggested the territory could be liable to compensation if it pushed ahead of the tolerance of the commonwealth, rather than waiting for the legalities to be settled.
(18) Same-sex marriage: supreme court's swing votes hang in the balance – live Read more The court heard legal arguments for two and a half hours, in a landmark challenge to state bans on same-sex marriage that is expected to yield a decision in June.
(19) The fairytales – which have been distributed by leaflet to universities around Singapore – include versions of Cinderella, the Three Little Pigs, Rapunzel and Snow White, each involving a reworked tale that relates to fertility, sex or marriage, and a resulting moral.
(20) It is likely that many of the girls end up working in brothels, but due to the stigma of being a sex worker they will usually report they were forced into marriage.