(n.) Relationship by marriage (as between a husband and his wife's blood relations, or between a wife and her husband's blood relations); -- in contradistinction to consanguinity, or relationship by blood; -- followed by with, to, or between.
(n.) Kinship generally; close agreement; relation; conformity; resemblance; connection; as, the affinity of sounds, of colors, or of languages.
(n.) Companionship; acquaintance.
(n.) That attraction which takes place, at an insensible distance, between the heterogeneous particles of bodies, and unites them to form chemical compounds; chemism; chemical or elective affinity or attraction.
(n.) A relation between species or highe/ groups dependent on resemblance in the whole plan of structure, and indicating community of origin.
(n.) A superior spiritual relationship or attraction held to exist sometimes between persons, esp. persons of the opposite sex; also, the man or woman who exerts such psychical or spiritual attraction.
Example Sentences:
(1) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(2) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(3) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(4) Because cystine in medium was converted rapidly to cysteine and cysteinyl-NAC in the presence of NAC and given that cysteine has a higher affinity for uptake by EC than cystine, we conclude that the enhanced uptake of radioactivity was in the form of cysteine and at least part of the stimulatory effect of NAC on EC glutathione was due to a formation of cysteine by a mixed disulfide reaction of NAC with cystine similar to that previously reported for Chinese hamster ovarian cells (R. D. Issels et al.
(5) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(6) This theory was confirmed by product analysis and by measuring the affinity of the substrate for the enzyme by its inhibition of p-nitrophenyl glucoside hydrolysis.
(7) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(8) ASF-II was purified to apparent homogeneity by using concanavalin A-agarose affinity chromatography, DEAE-cellulose chromatography, alumina gel adsorption, and isoelectric focussing techniques.
(9) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(10) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(11) The penicillin-resistant Enterococcus hirae R40 has a typical profile of membrane-bound penicillin-binding proteins (PBPs) except that the 71 kDa PBP5 of low penicillin affinity represents about 50% of all the PBPs present.
(12) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(13) Only estrogenic hormones are bound with high affinity.
(14) These results indicate that both the renal brush-border and basolateral membranes possess the Na(+)-dependent dicarboxylate transport system with very similar properties but with different substrate affinity and transport capacity.
(15) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(16) Neurotensin (NT) is an endogenous brain tridecapeptide for which high affinity binding sites exist in the central nervous system.
(17) In lactate medium the capacity of each AIB carrier is unchanged but its affinity is reduced to one-third.
(18) The telencephalon of teleost fish shows high affinity uptake for D-[3H]aspartate, intermediate levels of GABAergic markers and low levels of cholinergic enzymes.
(19) In all immunized rabbits the antisera obtained with the 7 alpha-derivative had a higher affinity and a narrower specificity than the antiserum obtained with the 7 beta-derivative.
(20) The binding parameters indicate that the principal activating effect of UMP is not simply to increase the affinity of the enzyme for glucose.
Fidelity
Definition:
(n.) Faithfulness; adherence to right; careful and exact observance of duty, or discharge of obligations.
(n.) Adherence to a person or party to which one is bound; loyalty.
(n.) Adherence to the marriage contract.
(n.) Adherence to truth; veracity; honesty.
Example Sentences:
(1) These lysates are comparable to those of Escherichia coli in transcriptional and translational fidelity and efficiency in response to a given template DNA.
(2) Procaryotic DNA polymerases contain an associated 3'----5' exonuclease activity which provides a proofreading function and contributes substantially to replication fidelity.
(3) In the current study, left ventricular geometry, loading conditions, and contractile state were assessed in 13 patients with nonischemic DCM with the use of simultaneous high-fidelity pressure measurements and echocardiographic recordings.
(4) "He was modelling himself at that time in Ethiopia on Che Guevara and Fidel Castro.
(5) A comparison of two different restriction enzymes, which cleave the plasmid with blunt or cohesive-ended double-strand breaks, did not reveal differences in repair fidelity.
(6) A major limitation of 3-D CT is its inability to reconstruct the pathology of soft tissues with the same fidelity afforded bony structures.
(7) The effect of metal activators on the fidelity of DNA synthesis has been examined.
(8) The spin-spin relaxation time T2 may be estimated using multiecho pulse sequences, but the accuracy of the estimate is dependent on the fidelity of the spin-echo amplitudes, which may be severely compromised by rf pulse and static field imperfections.
(9) The fidelity of base-matching is better in double-stranded transcripts synthesized on rat liver chromatin by homologous polymerase than in those synthesized on it by a bacterial polymerase, or in those synthesized by either of the two polymerases on pure DNA.
(10) Investors include Threadneedle, Fidelity, Blackrock and Standard Life.
(11) Rob Fisher, head of UK personal investments at Fidelity, thinks tax considerations alone make it worthwhile using the full limit.
(12) If you want full flexibility, you will probably have to switch your pension savings to a provider such as Hargreaves Lansdown, Fidelity or Aegon Retiready and manage it from their “platform”.
(13) Replication fidelity is shown to decrease roughly exponentially, and catalytic efficiency is shown to increase with diminishing returns, with the number of letters for a fixed genome length; hence their product, i.e.
(14) In Escherichia coli the dnaQ+ gene, which encodes epsilon, a fidelity subunit of DNA polymerase III, and the rnh+ gene, which encodes RNase H, share a promoter region but are transcribed in opposite directions.
(15) Unsurprisingly, Romney is polling ahead of his rival among Cuban Americans in Miami, where exiles have traditionally supported successive Republican candidates for their hardline stance against the communist regime of Fidel Castro and his brother Raúl.
(16) This indicates that elimination from the nucleotide pool of the oxidized form of guanine nucleotide is important for the high fidelity of DNA synthesis.
(17) Members of each subgroup have similar although not identical restriction maps and show relatively high but varying fidelities of DNA cross reassociation between members.
(18) They could be playing these people – Morales, Chesimard – off as pawns.” While Cuba was once an attractive destination for criminals, revolutionaries and skyjackers – 34 of 62 American plane hijackers flew to Cuba in 1969 – Fidel Castro lost patience with the swarm as early as the 70s.
(19) The high fidelity DNA synthesis in vitro by Thermococcus litoralis DNA polymerase provides good possibilities for maintaining the genetic information of original target DNA sequences intact in the DNA amplification applications.
(20) In Fidel's mind, he was probably acting in self-defence."