(n.) Relationship by marriage (as between a husband and his wife's blood relations, or between a wife and her husband's blood relations); -- in contradistinction to consanguinity, or relationship by blood; -- followed by with, to, or between.
(n.) Kinship generally; close agreement; relation; conformity; resemblance; connection; as, the affinity of sounds, of colors, or of languages.
(n.) Companionship; acquaintance.
(n.) That attraction which takes place, at an insensible distance, between the heterogeneous particles of bodies, and unites them to form chemical compounds; chemism; chemical or elective affinity or attraction.
(n.) A relation between species or highe/ groups dependent on resemblance in the whole plan of structure, and indicating community of origin.
(n.) A superior spiritual relationship or attraction held to exist sometimes between persons, esp. persons of the opposite sex; also, the man or woman who exerts such psychical or spiritual attraction.
Example Sentences:
(1) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(2) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(3) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(4) Because cystine in medium was converted rapidly to cysteine and cysteinyl-NAC in the presence of NAC and given that cysteine has a higher affinity for uptake by EC than cystine, we conclude that the enhanced uptake of radioactivity was in the form of cysteine and at least part of the stimulatory effect of NAC on EC glutathione was due to a formation of cysteine by a mixed disulfide reaction of NAC with cystine similar to that previously reported for Chinese hamster ovarian cells (R. D. Issels et al.
(5) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(6) This theory was confirmed by product analysis and by measuring the affinity of the substrate for the enzyme by its inhibition of p-nitrophenyl glucoside hydrolysis.
(7) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(8) ASF-II was purified to apparent homogeneity by using concanavalin A-agarose affinity chromatography, DEAE-cellulose chromatography, alumina gel adsorption, and isoelectric focussing techniques.
(9) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(10) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(11) The penicillin-resistant Enterococcus hirae R40 has a typical profile of membrane-bound penicillin-binding proteins (PBPs) except that the 71 kDa PBP5 of low penicillin affinity represents about 50% of all the PBPs present.
(12) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(13) Only estrogenic hormones are bound with high affinity.
(14) These results indicate that both the renal brush-border and basolateral membranes possess the Na(+)-dependent dicarboxylate transport system with very similar properties but with different substrate affinity and transport capacity.
(15) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(16) Neurotensin (NT) is an endogenous brain tridecapeptide for which high affinity binding sites exist in the central nervous system.
(17) In lactate medium the capacity of each AIB carrier is unchanged but its affinity is reduced to one-third.
(18) The telencephalon of teleost fish shows high affinity uptake for D-[3H]aspartate, intermediate levels of GABAergic markers and low levels of cholinergic enzymes.
(19) In all immunized rabbits the antisera obtained with the 7 alpha-derivative had a higher affinity and a narrower specificity than the antiserum obtained with the 7 beta-derivative.
(20) The binding parameters indicate that the principal activating effect of UMP is not simply to increase the affinity of the enzyme for glucose.
Fondness
Definition:
(n.) The quality or state of being fond; foolishness.
(n.) Doting affection; tender liking; strong appetite, propensity, or relish; as, he had a fondness for truffles.
Example Sentences:
(1) People have grown very fond of the first and fifth amendments,” she reports.
(2) But the large sums that undercut Hillary’s sudden fondness for economic populism will undercut Biden just as much, especially if raised conspicuously quickly.
(3) The original Wednesday Play, succeeded by the long-running Play for Today, is fondly remembered by many of today's best-known writers and directors as the experimental breeding ground for the likes of Dennis Potter, Ken Loach, Tony Garnett, Mike Leigh and Alan Bleasdale.
(4) Bomb them,” we tell Pakistan’s army, “crush them, hit them with all you have got.” Taliban were very fond of showing us videos of them killing us.
(5) I thought: this is a country of law and they will help me get my rights.” She is so fond of the child she looked after for 18 months that she feels ambivalent about any possible prosecution of the parents, her ex-employers.
(6) Another person fondly remembered childhood bed-times when she was comforted by Bournvita.
(7) The near-freebie prices amount to an especially generous giveaway to Venezuelans fond of large SUVs and gas-guzzling jalopies from the 1970s and 80s.
(8) John Londesborough Helsinki, Finland • We Finns are delighted to learn that Michael Booth is fond of us and would like us to rule the world.
(9) Since becoming Denmark's first female prime minister two years ago, Thorning-Schmidt has had to contend with the media nickname of "Gucci Helle", so called because of her fondness for designer clothes.
(10) "I have a fond memory of sitting in one of the dressing rooms, talking about Ireland in the 80s, and her showing me as many of her shamrock tattoos as possible.
(11) You are fond of citing the views of "the employers", along with horror stories about the significance of the international tables we're slipping down.
(12) As evidence of this new-found fondness, the album features a guest appearance from a local Salvation Army band.
(13) When France put an end to capital punishment in 1981, it also bid a not-so-fond farewell to the instrument of death that had taken the lives of thousands.
(14) But it clashed with other things.” Asked what his reaction would be now, he said: “I’d jump at it.” Blessed – who is also fondly remembered for another sci-fi role, appearing as Prince Vultan in the movie Flash Gordon – appeared to be a little confused about the Doctor’s surname, inaccurately suggesting the “Who” of the title was actually the character.
(15) He is fond of recalling what the late Labour leader John Smith told him the last time he appeared on his show - "You have a way of asking beguiling questions with potentially lethal consequences."
(16) If I'm extremely fond of a woman, if I think I might really wind up walking down the aisle again… I go in another direction."
(17) His knowledge of movies is vast – all kinds of movies, and I remember that he had a special fondness for genre pictures and for the work of Walter Hill and others – and he has always been very generous about sharing it with his readers.
(18) These films, of which the British are properly fond and proud, were made possible by a Frenchified Brazilian and the son of recent Jewish immigrants from eastern Europe.
(19) Previous chancellor Gordon Brown was fond of his fiscal "golden rule", but the only real golden rule of modern chancellors is never, ever raise the standard rate of income tax.
(20) His father, who was fond of humming the popular ballad Keep Right on to the End of the Road, lost his job in the great depression of the early 1930s.