What's the difference between affinity and harmony?

Affinity


Definition:

  • (n.) Relationship by marriage (as between a husband and his wife's blood relations, or between a wife and her husband's blood relations); -- in contradistinction to consanguinity, or relationship by blood; -- followed by with, to, or between.
  • (n.) Kinship generally; close agreement; relation; conformity; resemblance; connection; as, the affinity of sounds, of colors, or of languages.
  • (n.) Companionship; acquaintance.
  • (n.) That attraction which takes place, at an insensible distance, between the heterogeneous particles of bodies, and unites them to form chemical compounds; chemism; chemical or elective affinity or attraction.
  • (n.) A relation between species or highe/ groups dependent on resemblance in the whole plan of structure, and indicating community of origin.
  • (n.) A superior spiritual relationship or attraction held to exist sometimes between persons, esp. persons of the opposite sex; also, the man or woman who exerts such psychical or spiritual attraction.

Example Sentences:

  • (1) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
  • (2) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
  • (3) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
  • (4) Because cystine in medium was converted rapidly to cysteine and cysteinyl-NAC in the presence of NAC and given that cysteine has a higher affinity for uptake by EC than cystine, we conclude that the enhanced uptake of radioactivity was in the form of cysteine and at least part of the stimulatory effect of NAC on EC glutathione was due to a formation of cysteine by a mixed disulfide reaction of NAC with cystine similar to that previously reported for Chinese hamster ovarian cells (R. D. Issels et al.
  • (5) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
  • (6) This theory was confirmed by product analysis and by measuring the affinity of the substrate for the enzyme by its inhibition of p-nitrophenyl glucoside hydrolysis.
  • (7) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
  • (8) ASF-II was purified to apparent homogeneity by using concanavalin A-agarose affinity chromatography, DEAE-cellulose chromatography, alumina gel adsorption, and isoelectric focussing techniques.
  • (9) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
  • (10) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
  • (11) The penicillin-resistant Enterococcus hirae R40 has a typical profile of membrane-bound penicillin-binding proteins (PBPs) except that the 71 kDa PBP5 of low penicillin affinity represents about 50% of all the PBPs present.
  • (12) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
  • (13) Only estrogenic hormones are bound with high affinity.
  • (14) These results indicate that both the renal brush-border and basolateral membranes possess the Na(+)-dependent dicarboxylate transport system with very similar properties but with different substrate affinity and transport capacity.
  • (15) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
  • (16) Neurotensin (NT) is an endogenous brain tridecapeptide for which high affinity binding sites exist in the central nervous system.
  • (17) In lactate medium the capacity of each AIB carrier is unchanged but its affinity is reduced to one-third.
  • (18) The telencephalon of teleost fish shows high affinity uptake for D-[3H]aspartate, intermediate levels of GABAergic markers and low levels of cholinergic enzymes.
  • (19) In all immunized rabbits the antisera obtained with the 7 alpha-derivative had a higher affinity and a narrower specificity than the antiserum obtained with the 7 beta-derivative.
  • (20) The binding parameters indicate that the principal activating effect of UMP is not simply to increase the affinity of the enzyme for glucose.

Harmony


Definition:

  • (n.) The just adaptation of parts to each other, in any system or combination of things, or in things, or things intended to form a connected whole; such an agreement between the different parts of a design or composition as to produce unity of effect; as, the harmony of the universe.
  • (n.) Concord or agreement in facts, opinions, manners, interests, etc.; good correspondence; peace and friendship; as, good citizens live in harmony.
  • (n.) A literary work which brings together or arranges systematically parallel passages of historians respecting the same events, and shows their agreement or consistency; as, a harmony of the Gospels.
  • (n.) A succession of chords according to the rules of progression and modulation.
  • (n.) The science which treats of their construction and progression.
  • (n.) See Harmonic suture, under Harmonic.

Example Sentences:

  • (1) These concepts of facial harmony and surgical alterations have been difficult to teach in a residency program, especially regarding preoperative evaluation and a clear idea of the desired surgical results.
  • (2) The results will give Harmony 25 seats in Latvia’s 100-seat parliament, six fewer than they had before the elections, when they were also the largest single party in parliament.
  • (3) Japan has a long history of placing great value on the idea of harmony and respecting the rights of everyone,” she said.
  • (4) He has previously said the Anzac spirit had “informed our Australian culture and our character ever since that time, and I don’t think that lining it up with NAIDOC week, reconciliation day, harmony day and so on gives it the central focus that it deserves in our curriculum”.
  • (5) The grand mufti of Australia, Ibrahim Abu Mohammad, said Islam did not need a reformation “since the normative principles and practices of the religion allow Muslims to harmoniously coexist within pluralist societies that are based on the universal values of compassion and justice”.
  • (6) There are many differences between full dentures on Brånemark implants and fixed partial dentures built on the same type of implants: due to some more critical anatomical conditions, the choice of number, position and length of the implants is more delicate; the need of an harmonious crown-gingival tissue relationship; higher occlusal forces than in edentalous cases; difficulty in satisfying aesthetic requirements and ease of hygiene.
  • (7) Following the success of that release – and with the Beatles' Sgt Pepper's still months away – Brian Wilson imagined an orchestral and psychedelic suite showcasing the group's vocal harmonies.
  • (8) We also know little about the relative aptitude for different musical components, especially melody and harmony.
  • (9) In cultures at temperatures higher than necessary for optimum rates of growth the average lifetime of messenger RNA lengthened in harmony with the increased time required for cell division.
  • (10) Gay bishops have proved a headache for the archbishop of Canterbury, who has struggled to maintain harmony since taking office in 2002.
  • (11) A better conceptual balance needs to be struck between their harmonious and antagonistic functioning.
  • (12) A review of the literature shows little harmony between the results of this and various other studies.
  • (13) Induction by PB and MC of ER O-dealkylase, PR O-dealkylase and UDP-GT activities in ciliary NPE and PE cells was inhibited almost completely by 3.5 microM cyclohexamide and 40 nM actinomycin D. The heterogeneous distribution of these enzymes suggests that a harmonious interplay between NPE and PE cells is important for metabolic detoxification of blood plasma prior to aqueous humor formation.
  • (14) New Gambian leader Adama Barrow sworn in at ceremony in Senegal Read more But Jammeh, like most dictators, gives greater weight to his ego and grandeur over national peace and harmony.
  • (15) The utilization review department, as well as the medical staff, must work in close harmony with administration to assist the facility in surviving trying economical times.
  • (16) Up to half a million wolves once roamed across America , living in harmony with native Americans who revered them for supposed healing powers.
  • (17) While Victorians celebrated the empire on which the sun would never set with successive jubilees (golden, 1887, and diamond, 1897), many readers fretted over foreign (increasingly German) threats to the harmony of English life.
  • (18) Is this not a remarkable achievement, that we have such a diverse community and yet we live together so harmoniously?” Parramatta shooting: speculation is plentiful but the facts are few Read more Turnbull said: “And should we not ask ourselves: how did that happen?
  • (19) While those figures may be skewed by one film alone (Harmony Korine's hit teenage skin celebration Spring Breakers ) the overall pattern of sex bias is unmistakable.
  • (20) Working separately has, they say, been no bad thing for marital harmony.