(n.) Relationship by marriage (as between a husband and his wife's blood relations, or between a wife and her husband's blood relations); -- in contradistinction to consanguinity, or relationship by blood; -- followed by with, to, or between.
(n.) Kinship generally; close agreement; relation; conformity; resemblance; connection; as, the affinity of sounds, of colors, or of languages.
(n.) Companionship; acquaintance.
(n.) That attraction which takes place, at an insensible distance, between the heterogeneous particles of bodies, and unites them to form chemical compounds; chemism; chemical or elective affinity or attraction.
(n.) A relation between species or highe/ groups dependent on resemblance in the whole plan of structure, and indicating community of origin.
(n.) A superior spiritual relationship or attraction held to exist sometimes between persons, esp. persons of the opposite sex; also, the man or woman who exerts such psychical or spiritual attraction.
Example Sentences:
(1) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(2) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(3) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(4) Because cystine in medium was converted rapidly to cysteine and cysteinyl-NAC in the presence of NAC and given that cysteine has a higher affinity for uptake by EC than cystine, we conclude that the enhanced uptake of radioactivity was in the form of cysteine and at least part of the stimulatory effect of NAC on EC glutathione was due to a formation of cysteine by a mixed disulfide reaction of NAC with cystine similar to that previously reported for Chinese hamster ovarian cells (R. D. Issels et al.
(5) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(6) This theory was confirmed by product analysis and by measuring the affinity of the substrate for the enzyme by its inhibition of p-nitrophenyl glucoside hydrolysis.
(7) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(8) ASF-II was purified to apparent homogeneity by using concanavalin A-agarose affinity chromatography, DEAE-cellulose chromatography, alumina gel adsorption, and isoelectric focussing techniques.
(9) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(10) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(11) The penicillin-resistant Enterococcus hirae R40 has a typical profile of membrane-bound penicillin-binding proteins (PBPs) except that the 71 kDa PBP5 of low penicillin affinity represents about 50% of all the PBPs present.
(12) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(13) Only estrogenic hormones are bound with high affinity.
(14) These results indicate that both the renal brush-border and basolateral membranes possess the Na(+)-dependent dicarboxylate transport system with very similar properties but with different substrate affinity and transport capacity.
(15) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(16) Neurotensin (NT) is an endogenous brain tridecapeptide for which high affinity binding sites exist in the central nervous system.
(17) In lactate medium the capacity of each AIB carrier is unchanged but its affinity is reduced to one-third.
(18) The telencephalon of teleost fish shows high affinity uptake for D-[3H]aspartate, intermediate levels of GABAergic markers and low levels of cholinergic enzymes.
(19) In all immunized rabbits the antisera obtained with the 7 alpha-derivative had a higher affinity and a narrower specificity than the antiserum obtained with the 7 beta-derivative.
(20) The binding parameters indicate that the principal activating effect of UMP is not simply to increase the affinity of the enzyme for glucose.
Infinity
Definition:
(n.) Unlimited extent of time, space, or quantity; eternity; boundlessness; immensity.
(n.) Unlimited capacity, energy, excellence, or knowledge; as, the infinity of God and his perfections.
(n.) Endless or indefinite number; great multitude; as an infinity of beauties.
(n.) A quantity greater than any assignable quantity of the same kind.
(n.) That part of a line, or of a plane, or of space, which is infinitely distant. In modern geometry, parallel lines or planes are sometimes treated as lines or planes meeting at infinity.
Example Sentences:
(1) Multiple doses of cholestyramine significantly altered HCTZ kinetics, including reductions in Ae(0-24) by 35% (P less than 0.02), AUC(0-infinity) by 32% (P less than 0.01), and Cmax by 31% (P less than 0.01).
(2) The Infinity towel comes in colours more vibrant than one might expect from an eco-friendly product, including coral, green, blue and violet.
(3) In the interim, Gough had also played a devious old friend of the Doctor – by now, Peter Davison – in the 1983 story Arc of Infinity.
(4) The rate constants and steady-state values for m were in agreement with the Hodgkin-Huxley equations except that the experimental relationship of m(infinity) (3) against V was shifted 10-15 mV in the negative direction.
(5) 115 mM-TEA reduced the amplitude of [I(m)(0) - I(m)(infinity)] by about 85%.3.
(6) Some spoke of access to on-site rooftop infinity swimming pools and top of the range company cars.
(7) The final expression is mathematically accurate to 1% and is valid for image radii ranging from 20 to 500 mum and for exposure times from 30 ms to infinity.
(8) The data from the other 15 subjects showed small differences, which did not achieve statistical significance between the formulations with respect to Cmax, Tpeak and AUC0-infinity.
(9) We introduce the following functions of alpha m and beta m. (sequence in text) where VH, td and tau p stand for holding potential, constant delay time of 10 microseconds, and transit time of the transition velocity of alpha m (or beta m) from its initial value alpha om (or beta om) to its final steady value alpha infinity m (or beta infinity m), respectively.
(10) A second technician was arranged and claimed that BT often sells Infinity 2 for lines that can’t support the guaranteed speed.
(11) In adult myocytes, when EGTA (10 or 20 mM) or bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA, 10 mM) were included in the pipette solution, contractions were rapidly abolished, while a small (4 mV) shift of f infinity to more positive potentials was seen.
(12) By contrast, BT signed up 400,000 subscribers to its fibre product, Infinity, with 95,000 added in the last quarter.
(13) In the time-dependent transfer of a lipid from a donor to an acceptor vesicle population a(t) is the amount transferred to the acceptor vesicles at time t, a infinity is the equilibrium transfer value and a0 is the value at zero time.
(14) In the last quarter, 131,000 signed up for the BT Infinity fibre-to-the-cabinet product, which offers speeds of up to 76mbps and is being priced on a par with the fastest copper lines, meaning BT now has more than half a million fibre customers.
(15) We’re focusing on that right now with Infinity War while we’re breaking into those movies, [to see] which characters we can pull to the forefront who potentially haven’t had their own ‘A’ story arc to this point.
(16) After pulsed excitation with a polarized light, the fluorescence anisotropy ratio of DPH in membranes rapidly decreased and gave a final value (r infinity).
(17) The area under the plasma concentration-time curve from t = 0 to infinity (AUC infinity) of S(-)-mepivacaine was almost double that of R(+)-mepivacaine.
(18) From the results of intravenous injections one can deduce linear ibuprofen pharmacokinetics within the considered dosage range, with corresponding AUC0-infinity values of 3786 micrograms * min ml-1 and 7260 micrograms * min ml-1 for the 200 mg and 400 mg doses, respectively.
(19) The voltage dependence of the use-dependent block produced by cocaine isomers did not overlap with the activation of Na+ channels but did overlap with the steady-state inactivation (h infinity), indicating that cocaine can bind directly to the inactivated state of Na+ channels before channel opening.
(20) Following administration of 1000 mg MPA the areas under the plasma concentration-time curves (AUC 0-infinity) were calculated to (mean and S.E.