What's the difference between affinity and relationship?

Affinity


Definition:

  • (n.) Relationship by marriage (as between a husband and his wife's blood relations, or between a wife and her husband's blood relations); -- in contradistinction to consanguinity, or relationship by blood; -- followed by with, to, or between.
  • (n.) Kinship generally; close agreement; relation; conformity; resemblance; connection; as, the affinity of sounds, of colors, or of languages.
  • (n.) Companionship; acquaintance.
  • (n.) That attraction which takes place, at an insensible distance, between the heterogeneous particles of bodies, and unites them to form chemical compounds; chemism; chemical or elective affinity or attraction.
  • (n.) A relation between species or highe/ groups dependent on resemblance in the whole plan of structure, and indicating community of origin.
  • (n.) A superior spiritual relationship or attraction held to exist sometimes between persons, esp. persons of the opposite sex; also, the man or woman who exerts such psychical or spiritual attraction.

Example Sentences:

  • (1) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
  • (2) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
  • (3) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
  • (4) Because cystine in medium was converted rapidly to cysteine and cysteinyl-NAC in the presence of NAC and given that cysteine has a higher affinity for uptake by EC than cystine, we conclude that the enhanced uptake of radioactivity was in the form of cysteine and at least part of the stimulatory effect of NAC on EC glutathione was due to a formation of cysteine by a mixed disulfide reaction of NAC with cystine similar to that previously reported for Chinese hamster ovarian cells (R. D. Issels et al.
  • (5) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
  • (6) This theory was confirmed by product analysis and by measuring the affinity of the substrate for the enzyme by its inhibition of p-nitrophenyl glucoside hydrolysis.
  • (7) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
  • (8) ASF-II was purified to apparent homogeneity by using concanavalin A-agarose affinity chromatography, DEAE-cellulose chromatography, alumina gel adsorption, and isoelectric focussing techniques.
  • (9) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
  • (10) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
  • (11) The penicillin-resistant Enterococcus hirae R40 has a typical profile of membrane-bound penicillin-binding proteins (PBPs) except that the 71 kDa PBP5 of low penicillin affinity represents about 50% of all the PBPs present.
  • (12) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
  • (13) Only estrogenic hormones are bound with high affinity.
  • (14) These results indicate that both the renal brush-border and basolateral membranes possess the Na(+)-dependent dicarboxylate transport system with very similar properties but with different substrate affinity and transport capacity.
  • (15) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
  • (16) Neurotensin (NT) is an endogenous brain tridecapeptide for which high affinity binding sites exist in the central nervous system.
  • (17) In lactate medium the capacity of each AIB carrier is unchanged but its affinity is reduced to one-third.
  • (18) The telencephalon of teleost fish shows high affinity uptake for D-[3H]aspartate, intermediate levels of GABAergic markers and low levels of cholinergic enzymes.
  • (19) In all immunized rabbits the antisera obtained with the 7 alpha-derivative had a higher affinity and a narrower specificity than the antiserum obtained with the 7 beta-derivative.
  • (20) The binding parameters indicate that the principal activating effect of UMP is not simply to increase the affinity of the enzyme for glucose.

Relationship


Definition:

  • (n.) The state of being related by kindred, affinity, or other alliance.

Example Sentences:

  • (1) Cellulase regulation appears to depend upon a complex relationship involving catabolite repression, inhibition, and induction.
  • (2) The taxonomic relationship of strains H4-14 and 25a with previously described Xanthobacter strains was studied by numerical classification.
  • (3) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
  • (4) No consistent relationship could be found between the time interval from SAH to operation and the severity of vasospasm.
  • (5) The observed relationship between prorenin and renin substrate concentrations might be a consequence of their regulation by common factors.
  • (6) However, the relationships between sociometric status and social perception varied as a function of task.
  • (7) Phenotypic relationships were examined between final score and 13 type appraisal traits and first lactation milk yield from 2935 Ayrshire, 3154 Brown Swiss, 13,110 Guernsey, 50,422 Jersey, and 924 Milking Shorthorn records.
  • (8) A definite relationship between intelligence level and the type of muscle disease was found.
  • (9) After a discussion of the therapeutic relationship, several coping strategies which have been used successfully by many women are described and therapeutic applications are offered.
  • (10) The judge, Mr Justice John Royce, told George she was "cold" and "calculating", as further disturbing details of her relationship with the co-accused, Colin Blanchard and Angela Allen, emerged.
  • (11) To investigate the relationship between Helicobacter pylori infection and nonsteroidal anti-inflammatory drug (NSAID) intolerance and the effect of gold use on the seroprevalence of H. pylori.
  • (12) The main result of the correspondence analysis is a geometric map of this relationship showing how the relative frequencies of headache types change with age.
  • (13) A topographic relationship was recognized between the MM and the anterior thalamic nuclei.
  • (14) A J-shaped relationship with a dip at the middle SBP (140-149 mmHg) was recognized between treated SBP and CVD.
  • (15) This exploratory survey of 100 patients with rheumatoid arthritis (RA) was conducted (1) to learn about the types and frequencies of disability law-related problems encountered as a result of having RA, and (2) to assess the respective relationships between the number of disability law-related problems reported and the patients' sociodemographic and RA disease characteristics.
  • (16) To estimate the age of onset of these differences, and to assess their relationship to abdominal and gluteal adipocyte size, we measured adiposity, adipocyte size, and glucose and insulin concentrations during a glucose tolerance test in lean (less than 20% body fat), prepubertal children from each race.
  • (17) Comparison if single injections of MSB and atropine in normal subjects also demonstrated a more reliable dose-response relationship with MSB.
  • (18) Obesity in the Pimas is familial and has complex relationships with non-insulin-dependent diabetes mellitus, a common disease in this population.
  • (19) Reasonably good agreement is seen between theoretical apparent rate-vesicle concentration relationships and those measured experimentally.
  • (20) David Cameron has insisted that membership of the European Union is in Britain's national interest and vital for "millions of jobs and millions of families", as he urged his own backbenchers not to back calls for a referendum on the UK's relationship with Brussels.