What's the difference between afford and issue?

Afford


Definition:

  • (v. t.) To give forth; to supply, yield, or produce as the natural result, fruit, or issue; as, grapes afford wine; olives afford oil; the earth affords fruit; the sea affords an abundant supply of fish.
  • (v. t.) To give, grant, or confer, with a remoter reference to its being the natural result; to provide; to furnish; as, a good life affords consolation in old age.
  • (v. t.) To offer, provide, or supply, as in selling, granting, expending, with profit, or without loss or too great injury; as, A affords his goods cheaper than B; a man can afford a sum yearly in charity.
  • (v. t.) To incur, stand, or bear without serious detriment, as an act which might under other circumstances be injurious; -- with an auxiliary, as can, could, might, etc.; to be able or rich enough.

Example Sentences:

  • (1) Here we have asked whether protection from blood-borne antigens afforded by the blood-brain barrier is related to the lack of MHC expression.
  • (2) Adenosine diphosphate (ADP) afforded significant protection only at the very highest concentration (5.0 mM); inorganic pyrophosphate (PPi) did not protect against loss of latency at any concentration.
  • (3) HDAra-C in combination with anthracyclines is now considered to be a treatment which may afford some hope of a cure in a certain percentage of cases of adult acute non-lymphocytic leukemia.
  • (4) Worth an estimated $17.5bn each, they can afford it.
  • (5) A failure to reach a solution would potentially leave 200,000 homes without affordable cover, leaving owners unable to sell their properties and potentially exposing them to financial hardship.
  • (6) Our study suggests that a major part of the renal antimineralocorticoid activity of spironolactone may be attributable to minor sulfur-containing metabolites or their precursors having a high renal clearance that affords access to their site of activity via the renal tubular fluid.
  • (7) The presence of a previously unreported dipeptide transport mechanism within blood leukocytes and the selective enrichment of the granule enzyme, DPPI, within cytotoxic effector cells of lymphoid or myeloid lineage appear to afford a unique mechanism for the targeting of immunotherapeutic reagents composed of simple dipeptide esters or amides.
  • (8) Shorten said any arrangement needed to be consistent with international obligations, with asylum seekers afforded due process and their claims properly assessed.
  • (9) The primary focus of both nonpharmacologic and pharmacologic therapy should be to control systemic blood pressure in a simple, affordable, and nontoxic fashion that provides an adequate quality of life.
  • (10) Confirmation of the striking correlation between increased urinary ammonia and lowered neonatal ponderal index may afford a simple test for the identification of nutrient-related growth retardation.
  • (11) Based on the economics of most countries in Africa, their Health Budgets can afford mostly the non-opioid and strong opioid drugs in more or less adequate quantities.
  • (12) The headteacher of the school featured in the reality television series Educating Essex has described using his own money to buy a winter coat for a boy whose parents could not afford one, in a symptom of an escalating economic crisis that has seen the number of pupils in the area taking home food parcels triple in a year.
  • (13) It is hoped that up to 3,200 of the proposed new properties will be affordable homes and that the initiative will support up to 32,000 jobs.
  • (14) There are men who have been here for 15, 20 years or more who have never even sat in the cars because no one on the floor can afford to buy one.
  • (15) Santander's new mortgage range complements this, putting our relationship with our customers at the heart of our business and ensuring they get the right mortgage for them – one they can afford and which meets their needs."
  • (16) Uterine lavage affords the potential for non-invasive human blastocyst recovery, with obvious potential for preimplantation genetic diagnosis.
  • (17) Housing charity Shelter puts the shortage of affordable housing in England at between 40,000 and 60,000 homes a year.
  • (18) Streptozotocin and the haloethyl nitrosoureas, chlorozotocin and bis-chloroethylnitrosourea were less efficient in inducing HPRT-deficient mutants and a smaller degree of protection was afforded by the transfected genes.
  • (19) Fusing equimolecular amounts of 3-oxaspiro[5.5]undecane-2.4-dione with certain amino compounds afforded the corresponding N-substituted azaspirodiones.
  • (20) Apple could quite possibly afford to promise to pay out 80% of its streaming iTunes income, especially if such a service helped it sell more iPhones and iPads, where the margins are bigger.

Issue


Definition:

  • (n.) The act of passing or flowing out; a moving out from any inclosed place; egress; as, the issue of water from a pipe, of blood from a wound, of air from a bellows, of people from a house.
  • (n.) The act of sending out, or causing to go forth; delivery; issuance; as, the issue of an order from a commanding officer; the issue of money from a treasury.
  • (n.) That which passes, flows, or is sent out; the whole quantity sent forth or emitted at one time; as, an issue of bank notes; the daily issue of a newspaper.
  • (n.) Progeny; a child or children; offspring. In law, sometimes, in a general sense, all persons descended from a common ancestor; all lineal descendants.
  • (n.) Produce of the earth, or profits of land, tenements, or other property; as, A conveyed to B all his right for a term of years, with all the issues, rents, and profits.
  • (n.) A discharge of flux, as of blood.
  • (n.) An artificial ulcer, usually made in the fleshy part of the arm or leg, to produce the secretion and discharge of pus for the relief of some affected part.
  • (n.) The final outcome or result; upshot; conclusion; event; hence, contest; test; trial.
  • (n.) A point in debate or controversy on which the parties take affirmative and negative positions; a presentation of alternatives between which to choose or decide.
  • (n.) In pleading, a single material point of law or fact depending in the suit, which, being affirmed on the one side and denied on the other, is presented for determination. See General issue, under General, and Feigned issue, under Feigned.
  • (v. i.) To pass or flow out; to run out, as from any inclosed place.
  • (v. i.) To go out; to rush out; to sally forth; as, troops issued from the town, and attacked the besiegers.
  • (v. i.) To proceed, as from a source; as, water issues from springs; light issues from the sun.
  • (v. i.) To proceed, as progeny; to be derived; to be descended; to spring.
  • (v. i.) To extend; to pass or open; as, the path issues into the highway.
  • (v. i.) To be produced as an effect or result; to grow or accrue; to arise; to proceed; as, rents and profits issuing from land, tenements, or a capital stock.
  • (v. i.) To close; to end; to terminate; to turn out; as, we know not how the cause will issue.
  • (v. i.) In pleading, to come to a point in fact or law, on which the parties join issue.
  • (v. t.) To send out; to put into circulation; as, to issue notes from a bank.
  • (v. t.) To deliver for use; as, to issue provisions.
  • (v. t.) To send out officially; to deliver by authority; as, to issue an order; to issue a writ.

Example Sentences:

  • (1) You lot have got real issues to talk about and deal with.
  • (2) The issue of the Schizophrenia Bulletin is devoted to articles representing this full range of conceptual and empirical work on first-episode psychosis.
  • (3) I’m not in charge of it but he’s stood up and presented that, and when Jenny, you know, criticised it, or raised some issues about grandparent carers – 3,700 of them he calculated – he said “Let’s sit down”.
  • (4) Issues such as healthcare and the NHS, food banks, energy and the general cost of living were conspicuous by their absence.
  • (5) Before issuing the ruling, the judge Shaban El-Shamy read a lengthy series of remarks detailing what he described as a litany of ills committed by the Muslim Brotherhood, including “spreading chaos and seeking to bring down the Egyptian state”.
  • (6) Critics say he is unelectable as prime minister and will never be able to implement his plans, but he has nonetheless pulled attention back to an issue that many thought had gone away for good.
  • (7) Much of the current information concerning this issue is from short-term studies.
  • (8) It is entirely proper for serving judges to set out the arguments in high-profile cases to help public understanding of the legal issues, as long as it is done in an even-handed way.
  • (9) It has announced a four-stage programme of reforms that will tackle most of these stubborn and longstanding problems, including Cinderella issues such as how energy companies treat their small business customers.
  • (10) One man has died in storms sweeping across the UK that have brought 100-mile-an-hour winds and led to more than 50 flood warnings being issued with widespread disruption on the road and rail networks in much of southern England and Scotland.
  • (11) The issue has been raised by an accountant investigating the tax affairs of the duchy – an agricultural, commercial and residential landowner.
  • (12) They are just literally lying.” In August Microsoft severed its ties, saying Alec’s stance on climate change and several other issues “conflicted directly with Microsoft’s values”.
  • (13) One is that the issue of whether the World Cup should go ahead in Russia and Qatar still firmly remains on the table.
  • (14) The data indicate greater legitimacy and openness in discussing holocaust-related issues in the homes of ex-partisans than in the homes of ex-prisoners in concentration camps.
  • (15) That’s a criticism echoed by Democrats in the Senate, who issued a report earlier this month criticising Republicans for passing sweeping legislation in July to combat addiction , the Comprehensive Addiction and Recovery Act (Cara), but refusing to fund it.
  • (16) It can feel as though an official opinion has been issued.
  • (17) The first part of this survey which dealt with equipment for the anterior segment was published in a previous issue of this journal.
  • (18) Problem definition, the first step in policy development, includes identifying the issues, discussing and framing the issues, analyzing data and resources, and deciding on a problem definition.
  • (19) Heathrow, likewise, said Gatwick's new runway would not solve the issue of hub capacity.
  • (20) The deep green people who have an issue with the language of natural capital are actually making the same jump from value to commodification that they state that they don’t want ... They’ve equated one with the other,” he says.