What's the difference between aganglionic and ganglia?
Aganglionic
Definition:
(a.) Without ganglia.
Example Sentences:
(1) This study examined the function in vitro of aganglionic colon musculature in mice with hereditary aganglionosis--a strain of animals used as a model of Hirschsprung's disease.
(2) These results provide further evidence for the importance of the innervation of the aganglionic segment in Hirschsprung's disease.
(3) In studies of the pharmacology of a murine model of aganglionosis, the contracted aganglionic portion of the terminal bowel showed slow regular contractions of high amplitude in comparison to the rapid low-amplitude contractions of a normal segment of bowel.
(4) Histologically and histochemically, a total denervation state was observed in the aganglionic segment, in contrast to findings in narrow segments of Hirschsprung's disease, in which intramural extraneous nerves are known to be increased.
(5) Hirschsprung disease, or congenital aganglionic megacolon, is commonly assumed to be a sex-modified multifactorial trait.
(6) The concentration of immunoreactive PACAP was lower in the aganglionic than in the ganglionic segment of the intestinal wall.
(7) This study examined the projections in vitro of excitatory and inhibitory colonic motor nerves in the unaffected siblings of mice with hereditary aganglionic colon--a strain of animals used as a model of Hirschsprung's disease.
(8) Hirschsprung's disease is characterized by a single aganglionic segment of colon extending distally to the anal margin.
(9) Distal aganglionic (Hirschsprung) bowel often showed a rich supply of nerves within the muscle layers and there was no obvious morphological abnormality of constituent axons.
(10) Nine cases out of a series of 319 aganglionisms seen between 1957 and 1977 are reported.
(11) A pressure reducing operation (a sphincteromyotomy) is indicated in ultrashort aganglionic segments, in special cases of elongated sigma, in cases of prolonged constipation after sigma resection and with disturbed reflex mechanism, in cases of sphincter inhibition syndrome, and in children with paradox reflex mechanism.
(12) In the aganglionic colon, greatly diminished numbers of vasoactive intestinal polypeptide-like immunoreactive nerve fibers were found in the circular muscle layer, lamina propria of the mucosa, and in the submucosa.
(13) It is concluded that cholinergic innervation is congenitally absent in the aganglionic rectum in piebald lethal mice.
(14) The acetyl choline threshold is higher in aganglionic muscle strips.
(15) SOM-LI nerve fibres were widely distributed in the aganglionic bowel.
(16) Ileoanal pull-through was performed in 18 TCA rats, in conjunction with the Martin extended Duhamel procedure using the entire colon in six rats, with an aganglionic colon patch in nine (using the right [3 rats], transverse [3 rats] and left [3 rats] colon), and without other procedures in three rats.
(17) The larger nerve trunks of aganglionic bowel frequently contained myelinated axons and these have been observed within the myenteric plexus of normal rectum.
(18) In cases of Hirschsprung's disease with aganglionic segment confined to the rectum, even severe symptoms can subside considerably at some time or other usually before the age of 20.
(19) Aganglionosis is the result either of a defect in vagal neural crest migration or in the microenvironment over an extended area of the bowel and not just in the terminal aganglionic colon.
(20) In the control untreated tissues, 5-HT-like immunoreactive fibers were observed neither in the normoganglionic nor in the aganglionic regions.
Ganglia
Definition:
(pl. ) of Ganglion
Example Sentences:
(1) Brain and ganglia of embryonic Periplaneta americana were grown for 2 to 3 weeks in a chemically defined medium.
(2) In schizophrenic patients the density of dopamine uptake sites in the basal ganglia was slightly reduced, mainly in the middle third of putamen.
(3) Increased iron levels in basal ganglia were generally associated with normal or elevated levels of ferritin immunoreactivity, for example, the substantia nigra in PSP and possibly MSA, and in putamen in MSA.
(4) The guanethidine treatment resulted in an 86% absolute reduction in cell number in the superior cervical ganglia of 15 day old rats.
(5) Following injections of HRP into the apex of the heart, the sinoatrial (SA) nodal region and the ventral wall of the right ventricle, we observed that HRP-labeled sympathetic neurons were localized predominantly in the right stellate ganglia, and to a lesser extent, in the right superior and middle cervical ganglia, and left stellate ganglia.
(6) We have characterized previously a model of herpes simplex virus (HSV) infection of rat dorsal root ganglia (DRG) following cutaneous infection.
(7) CGRP was localised by immunocytochemistry to both nerves and ganglia in human airways.
(8) We have also studied the distribution of tenascin mRNA in the developing spinal cord and spinal ganglia.
(9) Descending neurons have opposite structural polarity, arising in the brain and terminating in segmental regions of the fused ventral ganglia.
(10) Finally, fosinopril had no effect on the pressor or chronotropic effects of norepinephrine (NE) or 1,1-dimethyl-4-phenylpiperinium (DMPP) or electrical stimulation of the sympathetic ganglia of pithed rats.
(11) Translocation occurred after behavioral training of the animal and after application to isolated ganglia of serotonin or phorbol esters.
(12) Blastemas implanted with 2 dorsal root ganglia and simultaneously denervated 14 days after amputation exhibited control levels of cell cycle activity 6 days later, as measured by 3H-thymidine pulse labeling.
(13) It leads to ganglia formation due to mucoid liquefaction.
(14) The deficit in final accuracy in the absence of visual feedback reflects the important role played by the basal ganglia in sensorimotor integration.
(15) They have similar axon trajectories into the thoracic ganglia, where they invade functionally related neuropils.
(16) This agrees with previous ultrastructural observations that, in small mammals, neither basement membranes nor large connective tissue spaces are found inside enteric ganglia.
(17) These include persisting HSVI of only the distal sensible or vegetative neurones and recurrence of infection with further destruction of ganglia-cells.
(18) These observations support the concept that latent infection of sensory ganglia may be the source of virus in recurrent herpetic disease in man.
(19) In contrast, another enzyme associated with glutamate metabolism, aspartate aminotransferase, is rather uniformly distributed within neurons of the sensory ganglia.
(20) Huntington's disease is a dominantly inherited, progressive neurodegenerative disorder causing marked pathology in the basal ganglia.