(a.) Acting; -- opposed to patient, or sustaining, action.
(n.) One who exerts power, or has the power to act; an actor.
(n.) One who acts for, or in the place of, another, by authority from him; one intrusted with the business of another; a substitute; a deputy; a factor.
(n.) An active power or cause; that which has the power to produce an effect; as, a physical, chemical, or medicinal agent; as, heat is a powerful agent.
Example Sentences:
(1) Combinations of maximum amounts of glucagon and the cyclic nucleotide did not produce a greater effect than either agent alone.
(2) Assessment of the likelihood of replication in humans has included in vitro exposure of human cells to the potential pesticidal agent.
(3) In addition, intravenous injection of complexes into rabbits showed optimal myocardial images with agents of intermediate lipophilicity.
(4) This study examined the [3H]5-HT-releasing properties of 3,4-methylenedioxymethamphetamine (MDMA) and related agents, all of which cause significant release of [3H]5-HT from rat brain synaptosomes.
(5) The quaternary structure of ribonucleotide reductase of Escherichia coli was investigated, with the use of purified B1 and B2 proteins and bifunctional cross-linking agents.
(6) Rapid overgrowth of all cultures with the E. coli necessitated the use of selective media containing antimicrobial agents to which the E. coli was sensitive.
(7) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(8) of PLA2 caused marked degranulation of mast cells in the rat mesentery which was facilitated by addition of calcium ion (10 mM) but antagonized by pretreating with three antiinflammatory agents.
(9) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(10) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(11) The secondary leukemia that occurred in these patients could be distinguished from the secondary leukemia that occurs after treatment with alkylating agents by the following: a shorter latency period; a predominance of monocytic or myelomonocytic features; and frequent cytogenetic abnormalities involving 11q23.
(12) The agent present in the serum which causes dissolution of the fibrin clot was isolated and identified as pepsinogen.
(13) The active agents modestly improved treadmill exercise duration time until 1 mm ST segment depression (3%), and only propranolol and diltiazem had significant effects.
(14) Maximal covalent binding of [4,5-14C]ronidazole to DNA also required four-electron reduction, consistent with previous studies of the covalent binding of this agent to immobilized sulfhydryl groups [Kedderis et al.
(15) Since interferon alfa-2b (Intron A) is useful as a single agent, it is important to determine if interferon can be combined with standard chemotherapy to improve both response and survival in patients with cancer.
(16) Median effect analysis was applied for the evaluation of in vitro effect by the growth inhibition, and the in vivo effect by comparison of the increase of life span (ILS) in a combined group with the sum of ILS's in 2 single agent groups.
(17) Noradrenaline (NA) was released from sympathetic nerve endings in the tissue by electrical stimulation of the mesenteric nerves or by the indirect sympathomimetic agent tyramine.
(18) Helsby, who joined the estate agent in 1980, saw his basic salary unchanged at £225,000, but gains a £610,000 windfall in shares, available from May, as well as a £363,000 increase in cash and shares under the company profits-sharing scheme.
(19) Combining maximally effective concentrations of each of these stimulating agents produces an additive increase in both the level of 32P incorporation into tyrosine hydroxylase and the degree of activation of the enzyme.
(20) The review provides an update of drug-induced pulmonary disorders, focusing on newer agents whose effects on the lung have been studied recently.
Vehicle
Definition:
(n.) That in or on which any person or thing is, or may be, carried, as a coach, carriage, wagon, cart, car, sleigh, bicycle, etc.; a means of conveyance; specifically, a means of conveyance upon land.
(n.) That which is used as the instrument of conveyance or communication; as, matter is the vehicle of energy.
(n.) A substance in which medicine is taken.
(n.) Any liquid with which a pigment is applied, including whatever gum, wax, or glutinous or adhesive substance is combined with it.
Example Sentences:
(1) They broke in with a battering ram: an armoured vehicle known as a Bearcat.
(2) Six of 7 SAO shock rats treated with U74006F survived for 120 min following reperfusion, while none of 7 SAO shock rats given the vehicle survived for 120 min (P less than .01).
(3) It would be "very easy to manipulate and access one of our vehicles", he said.
(4) A group of rats raised on D-P++ for 4 weeks were fed D-P- for 7 days after which they received 500 pmol of 1,25-dihydroxyvitamin D3 [1,25(OH)2D3; SUPP] or an equal volume of the vehicle (ETH).
(5) Neonatal treatment with a low dose of the estrogen diethylstilbestrol (DES) had no significant effect on adult estrogen binding within the assayed vaginal compartments; however, this treatment caused a 2-fold increase in the level of cytosolic progestin binding in the vaginal FMW over that in vehicle-treated mice.
(6) Each subject applied a vehicle cream containing 0.075% capsaicin (Axsain, GalenPharma Inc.) to a 4 cm2 area of skin on one volar forearm and vehicle alone to an identical treatment area on the other forearm, according to a double-blind procedure.
(7) Utilizing the bilateral comparison technique in 30 hospitalized patients with chronic stable plaque-type psoriasis vulgaris, we closely monitored the clinical responses to ultraviolet radiation (Westinghouse fluorescent FS40 bulbs, 290--400 nm) and a variety of tar preparations and lubricant vehicles in combination and separately.
(8) Controls were injected in the same manner with vehicle and microspheres.
(9) Sympathetic nervous system function was blocked in developing male SHR by treating pups from days 0 to 14 with: (1) guanethidine, (2) combined alpha- and beta-receptor antagonists (prazosin and timolol), or (3) vehicle (5% sucrose).
(10) The most common seenario was a vehicle-vehicle collision in which seat belts were not used and the decedent or the decedent's driver was at fault.
(11) Thus, the lymphoid population containing cell-mediated anti-idiotypic responsiveness served as a vehicle of resistance.
(12) Well known buyout firms such as Blackstone and Carlyle appear in the leaked documents, and Luxembourg investment vehicles are commonplace in such investment firms.
(13) Future studies will need to carefully evaluate the vehicle used and the strength of topical CsA employed.
(14) The Calspan 3-D Computer Simulator of a Motor Vehicle Crash Victim was used to provide estimates of the head and neck response to be expected for the very specific deceleration profiles simulated.
(15) "There were around 50 attackers, heavily armed in three vehicles, and they were flying the Shebab flag," Maisori added, speaking from the town, where several buildings including hotels, restaurants, banks and government offices were razed to the ground.
(16) Two officers who witnessed the shooting of unarmed 43-year-old Samuel DuBose in Cincinnati will not face criminal charges, despite seemingly corroborating a false claim that DuBose’s vehicle dragged officer Ray Tensing before he was fatally shot.
(17) Vehicle administration had no effect on pulmonary function.
(18) The best was the oral version of the Symbol Digit Modalities test, which by itself accounted for 70% of the variance of the full-sized-vehicle driving score.
(19) II with melatonin instead of 25.9% in the corresponding vehicle controls.
(20) Twenty-four h prior to the measurement of 45Ca2+ uptake, the cells were transferred to serum-free medium ([Ca2+], 1.0 mM) containing 1.0 nM 1,25(OH)2D3 or vehicle.