(v. t.) To bring together; to collect into a mass or sum. "The aggregated soil."
(v. t.) To add or unite, as, a person, to an association.
(v. t.) To amount in the aggregate to; as, ten loads, aggregating five hundred bushels.
(a.) Formed by a collection of particulars into a whole mass or sum; collective.
(a.) Formed into clusters or groups of lobules; as, aggregate glands.
(a.) Composed of several florets within a common involucre, as in the daisy; or of several carpels formed from one flower, as in the raspberry.
(a.) Having the several component parts adherent to each other only to such a degree as to be separable by mechanical means.
(a.) United into a common organized mass; -- said of certain compound animals.
(n.) A mass, assemblage, or sum of particulars; as, a house is an aggregate of stone, brick, timber, etc.
(n.) A mass formed by the union of homogeneous particles; -- in distinction from a compound, formed by the union of heterogeneous particles.
Example Sentences:
(1) Aggregation was more frequent in low-osmolal media: mainly rouleaux were formed in ioxaglate but irregular aggregates in non-ionic media.
(2) We have examined overlapping octapeptides from the kappa IIIb light chain variable region and show that some framework peptides have the ability to bind aggregated IgG.
(3) Platelet-rich plasma (PRP) was prepared, and platelet aggregation studies were conducted directly or conducted on washed platelets prepared from PRP collected with ACD.
(4) Macrophages internalize aggregated low density lipoprotein (LDL) by LDL receptor-dependent phagocytosis.
(5) Cicaprost is an orally available analogue of PGI2 and has been shown to inhibit platelet aggregation in both in vitro and animal studies.
(6) Only IgG2a and IgG2b myeloma proteins bound readily to IC-21 Fc-receptors, the former in nonaggregated as well as aggregated form, the latter only as aggregated complexes.
(7) When the aggregates occurred on the cell periphery their position coincided with areas free of lamellae.
(8) 2-(4'-Isobutylphenyl)propionic acid, ibuprofen, is an antiinflammatory agent which possesses moderate platelet aggregation inhibitory activity.
(9) In addition, spontaneous platelet aggregation is increased when vegetations are present on cardiac valves.
(10) At concentrations several hundredfold higher than the equivalents present in the minimum concentration of rat skin soluble collagen required for platelet aggregation, neither Hyl-Gal (at 29 muM) nor Hyl-Gal-Glc (at 18 muM) caused platelet aggregation or inhibited platelet aggregation by native collagen.
(11) The mechanisms leading to spontaneous platelet aggregation and thrombocytopenia appear to be similar to those described for other patients with type IIB vWD.
(12) There is approximately a 25% decrease in aggregation from regions of the rib distal to the metaphyseal-growth plate junction (69%) to the region proximal to it (50%).
(13) Laboratory data were aggregated similarly within each study, using the last active drug as a grouping factor.
(14) No correlation could be found between DS content and state of aggregation.
(15) The synthetic S-nitroso-thiol, S-nitroso-N-acetylcysteine, markedly inhibited platelet aggregation with an IC50 of 6 nM.
(16) On the other hand, ultraviolet (320-nm) light, absorbed by 3-hydroxy-pyridinium cross-links which were rapidly photolyzed, partially dissociated polymeric collagen aggregates from bovine Achilles tendon after subsequent heating.
(17) The ternary complex consisting of a 65-kDa peptide originating from the proteoglycan core protein and a 43-kDa link protein bound to hyaluronic acid was purified from a clostripain digest of the rat chondrosarcoma aggregating proteoglycan and 14C-carbamylated with potassium [14C]cyanate.
(18) The IC50 on arachidonic acid-induced platelet aggregation was: fisetin, 22 microM; kaempferol, 20 microM; quercetin, 13 microM; morin, 150 microM less than IC50 less than 300 microM.
(19) Changes in the determinants of blood viscosity (packed cell volume, plasma viscosity, red cell aggregation, and red cell deformability) were studied on day 1 and day 5.
(20) Released aggregates of the 19.6-kDa protein were removed from suspension by ultracentrifugation and separated from contaminating membranes by washing in 1.0% sodium dodecyl sulfate (SDS).
Demonstration
Definition:
(n.) The act of demonstrating; an exhibition; proof; especially, proof beyond the possibility of doubt; indubitable evidence, to the senses or reason.
(n.) An expression, as of the feelings, by outward signs; a manifestation; a show.
(n.) The exhibition and explanation of a dissection or other anatomical preparation.
(n.) (Mil.) a decisive exhibition of force, or a movement indicating an attack.
(n.) The act of proving by the syllogistic process, or the proof itself.
(n.) A course of reasoning showing that a certain result is a necessary consequence of assumed premises; -- these premises being definitions, axioms, and previously established propositions.
Example Sentences:
(1) The Na+ ionophore, gramicidin, had a small but significant inhibitory effect on Na(+)-dependent KG uptake, demonstrating that KG uptake was not the result of an intravesicular positive Na+ diffusion potential.
(2) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(3) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(4) Of the patients 73% demonstrated clinically normal sensibility test results within 23 days after operation.
(5) Lucy and Ed will combine coverage of hard and breaking news with a commitment to investigative journalism, which their track record so clearly demonstrates”.
(6) These immunocytochemical studies clearly demonstrated that cells encountered within the fibrous intimal thickening in the vein graft were inevitably smooth muscle cell in origin.
(7) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(8) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(9) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(10) Intravesical BCG is clearly superior to oral BCG, and controlled studies have demonstrated that percutaneous administration is not necessary.
(11) We have previously shown that serotonin is present in secretory granules of frog adrenochromaffin cells; concurrently, we have demonstrated that serotonin is a potent stimulator of corticosterone and aldosterone secretion by adrenocortical cells.
(12) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(13) The results demonstrated that K2PtCl4 was bound to a greater degree than CDDP in this system with 3-5 and 1-2 platinum atoms respectively, bound per transferrin molecule.
(14) These studies, in addition to demonstrating that the placenta contains TRH deamidase activity, suggest that losses of fetal TRH through the placenta are not large.
(15) Light microscopic studies of pancreata from mice sacrificed at this time demonstrated insulitis and beta cell necrosis.
(16) Western blot analysis of these mitochondria using an antibody against carnitine palmitoyltransferase II purified from beef heart demonstrates a 68-kDa protein, which under ischemic conditions apparently is decreased by 2 kDa.
(17) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(18) In 1 of the 3, anterior capsular detachment was also demonstrated radiographically and confirmed surgically.
(19) This result demonstrates that branching enzyme belongs to a family of the amylolytic enzymes.
(20) Histological studies of nerves 2 years following irradiation demonstrated loss of axons and myelin, with a corresponding increase in endoneurial, perineurial, and epineurial connective tissue.