(n.) The act of aggregating, or the state of being aggregated; collection into a mass or sum; a collection of particulars; an aggregate.
Example Sentences:
(1) Aggregation was more frequent in low-osmolal media: mainly rouleaux were formed in ioxaglate but irregular aggregates in non-ionic media.
(2) We have examined overlapping octapeptides from the kappa IIIb light chain variable region and show that some framework peptides have the ability to bind aggregated IgG.
(3) Platelet-rich plasma (PRP) was prepared, and platelet aggregation studies were conducted directly or conducted on washed platelets prepared from PRP collected with ACD.
(4) Macrophages internalize aggregated low density lipoprotein (LDL) by LDL receptor-dependent phagocytosis.
(5) Cicaprost is an orally available analogue of PGI2 and has been shown to inhibit platelet aggregation in both in vitro and animal studies.
(6) Only IgG2a and IgG2b myeloma proteins bound readily to IC-21 Fc-receptors, the former in nonaggregated as well as aggregated form, the latter only as aggregated complexes.
(7) When the aggregates occurred on the cell periphery their position coincided with areas free of lamellae.
(8) 2-(4'-Isobutylphenyl)propionic acid, ibuprofen, is an antiinflammatory agent which possesses moderate platelet aggregation inhibitory activity.
(9) In addition, spontaneous platelet aggregation is increased when vegetations are present on cardiac valves.
(10) At concentrations several hundredfold higher than the equivalents present in the minimum concentration of rat skin soluble collagen required for platelet aggregation, neither Hyl-Gal (at 29 muM) nor Hyl-Gal-Glc (at 18 muM) caused platelet aggregation or inhibited platelet aggregation by native collagen.
(11) The mechanisms leading to spontaneous platelet aggregation and thrombocytopenia appear to be similar to those described for other patients with type IIB vWD.
(12) There is approximately a 25% decrease in aggregation from regions of the rib distal to the metaphyseal-growth plate junction (69%) to the region proximal to it (50%).
(13) Laboratory data were aggregated similarly within each study, using the last active drug as a grouping factor.
(14) No correlation could be found between DS content and state of aggregation.
(15) The synthetic S-nitroso-thiol, S-nitroso-N-acetylcysteine, markedly inhibited platelet aggregation with an IC50 of 6 nM.
(16) On the other hand, ultraviolet (320-nm) light, absorbed by 3-hydroxy-pyridinium cross-links which were rapidly photolyzed, partially dissociated polymeric collagen aggregates from bovine Achilles tendon after subsequent heating.
(17) The ternary complex consisting of a 65-kDa peptide originating from the proteoglycan core protein and a 43-kDa link protein bound to hyaluronic acid was purified from a clostripain digest of the rat chondrosarcoma aggregating proteoglycan and 14C-carbamylated with potassium [14C]cyanate.
(18) The IC50 on arachidonic acid-induced platelet aggregation was: fisetin, 22 microM; kaempferol, 20 microM; quercetin, 13 microM; morin, 150 microM less than IC50 less than 300 microM.
(19) Changes in the determinants of blood viscosity (packed cell volume, plasma viscosity, red cell aggregation, and red cell deformability) were studied on day 1 and day 5.
(20) Released aggregates of the 19.6-kDa protein were removed from suspension by ultracentrifugation and separated from contaminating membranes by washing in 1.0% sodium dodecyl sulfate (SDS).
Coalescence
Definition:
(n.) The act or state of growing together, as similar parts; the act of uniting by natural affinity or attraction; the state of being united; union; concretion.
Example Sentences:
(1) Above 160 K, the line position in Mb* shifts again and coalesces with the value of Mb for temperatures above 200 K. The shift is accompanied by an increase of the line area, reflecting a slowing of rebinding kinetics.
(2) Thus when the implant consisted of compound cranial half-somites, giant, coalesced ganglia developed, encompassing the entire length of the graft.
(3) Enlargement and coalescence of intercellular spaces gave rise to intertrabecular channels.
(4) Light and electron microscopic examination of the central and peripheral nervous systems showed that intramyelinic vacuolation developed in the white matter of brain and cord within 12 h. The intramyelinic vacuolation in the white matter of brain and cord became more severe with longer survival, vacuoles coalescing and secondary axonal degeneration becoming evident.
(5) Chemical dehydration with 2,2-dimethoxypropane was used to convert an albumin emulsion into an albumin suspension and to reduce coalescence.
(6) Scanning electron microscopic studies of myoblasts from 11- to 13-day-old chick embroyonic breast muscle cultured on collagen-coated glass coverslips showed six stages of development into multinucleated myotubes: (1) growth of flattened, spread-out cells for 20-30 hr following initiation of monolayer cultures; (2) extension of microprocesses (1-150 microM) from cells that have become spindle shaped; (3) contact and adherence of microprocesses from adjacent cells; (4) thickening of fused processes; (5) approximation of the cells; and (6) coalescence of the cells to form a spindle-shaped myotube.
(7) The author describes the experiences, the series of "apprenticeships" and clinical exposures, which coalesced into his education, from teenage days in the New York Madison House settlement, through Harvard undergraduate and graduate work, to Worcester State Hospital as head of psychological services and research.
(8) Very young parasites lack the pigment but deposits of pigment appear and coalesce into dense deposits within the parasite as it grows.
(9) These occured as small beaded and larger coalescent masses which varied in metachromasia.
(10) The focal adhesions which are typical of the spread chick RPE cells in vitro consist of several closely apposed focal contacts, arranged in a parallel fashion, which are often coalesced with each other along their sides.
(11) The lesion begins with cytoplasmic vacuolar degeneration of the arterial smooth-muscle cells, which then progresses to coalescence of vacuoles, leading to disruption of the media, intramural hemorrhage, and periadventitial fibrin deposition.
(12) Four months postbiopsy the patient is asymptomatic but with the coalesced white plaques remaining.
(13) In 10- and 16-day grafts, continuity between ventricular and graft lumina was established and coalescence of graft pieces was apparent.
(14) These lesions, which may be smaller but often are larger than the iris lesions in conventional erythema multiforme, tend to coalesce into plaques and reveal a papulovesicular component at their periphery.
(15) Computed tomographic findings suggest the tumor begins as multiple hepatic nodules that grow and coalesce, forming large confluent masses preferentially involving the liver periphery.
(16) These findings, supported by simulation results, allow one to apply the theoretical results of the coalescence process directly to the allelic genealogy.
(17) This arose by the formation of large glycogen lakes, which coalesced and then lost their glycogen content, and this was accompanied by nuclear irregularity and shrinkage.
(18) Oil bodies isolated from mature maize (Zea mays) embryos maintained their discreteness, but coalesced after treatment with trypsin but not with phospholipase A2 or C. Phospholipase A2 or C exerted its activity on oil bodies only after the exposed portion of oleosins had been removed by trypsin.
(19) The ring-shaped elements of the RV and the moderately electron-dense material of the MDV were released exocytotically somewhat later; these materials coalesced in the perivitelline space to form a new coat (envelope 2).
(20) Following heated public debate over the issue of top-slicing the BBC licence fee, opinion at the broadcasters and the Department for Culture, Media and Sport is now coalescing around a less overt method of the corporation helping with Channel 4's future funding needs.