(a.) Having marks or patches of different colors; as, variegated leaves, or flowers.
Example Sentences:
(1) For the second propositus, a woman presenting with abdominal and psychiatric manifestations, the age of onset was 38 years; the acute attack had no recognizable cause; she had mild skin lesions and initially was incorrectly diagnosed as intermittent acute porphyria; the diagnosis of variegate porphyria was only established at the age of 50 years.
(2) Such characteristics are reminiscent of the behavior of variegating position-effects in Drosophila and the application of this paradigm to human disease phenotypes provides both a mechanism by which differential genome imprinting may be accomplished as well as genetic models that may explain the clinical association of syntenic diseases, the association between tumor progression and specific chromosomal aneuploidy and the unusual inheritance characteristics of many diseases.
(3) The diagnosis depends on fecal excretion of porphyrins, which is greatly increased in variegate porphyria and consists predominantly of protoporphyrin.
(4) Although clinical improvements occurred in the case of variegate porphyria, the results were inconclusive for reasons given.
(5) Appropriate laboratory tests on urine and feces samples are necessary to distinguish between PCTS and variegate porphyria when a young woman presents with the skin lesions characteristic of cutaneous hepatic porphyrias.
(6) One patient with variegate prophyria and two with hereditary coproporphyria had an attack related to pregnancy.
(7) The theory of the unconscious that arises from the method of direct interpretation reflects a differentiated inner world with variegated landscapes of images and frameworks.
(8) The faecal porphyrin patterns of 24 patients with porphyria cutanea tarda symptomatica (PCTS), eight patients with variegate porphyria, three patients with other types of porphyria, and 20 non-porphyrics subjects have been compared using a two-demensional thin layer chromatographic technique that separates porphyrins of the isocoproporphyrin series from other faecal porphyrins.
(9) A 62-year-old man with variegate porphyria is reported.
(10) Four patients with variegate porphyria (VP) were treated with repeated haem arginate infusions daily for 4 days and then weekly for 4 weeks.
(11) Hence, the differences in binding of the w+ gene probe in the variegating and variegation-suppressed strains reflect differences in chromosomal packaging rather than alterations in gene number.
(12) The lesions appeared brownish black, and most were variegated from tan to black.
(13) Thus, mice with variegating transgenes can provide molecular access to gene control mechanisms and to their consequences in development and disease.
(14) The results provide some indication as to the mechanism and timing for the general suppression of position-effect variegation by supernumerary heterochromatin in the genome.
(15) Beautiful and ancient plants, such as spreading bellflower , could become extinct in some places through the escape of variegated yellow archangel from gardens.
(16) Variegated endocrine cells were documented within this lining, using immunohistochemical and ultrastructural techniques.
(18) In white-mottled (wm) position-effect variegation mutants, a significant correlation was found between the extent of variegation (percentage of yellow cells) and riboflavin content (growth effect) of the MT.
(19) Four patients suffering from variegate prophyria were investigated during acute attacks.
(20) These changes include variegated hyperplasia of the pulp with epithelioid cells, mature eosinophilic granulocytes and immunoblasts occasionally resembling Hodgkin cells.