(1) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
(2) Under conditions of 5-HT1-like, 5-HT2 and 5-HT3 receptor blockade, the following rank order of agonism was observed: 5-HT > 5-methoxytryptamine = renzapride > (S)-zacopride > (R,S-zacopride > 5-carboxamidotryptamine > BRL 24682 > (R-zacopride > metoclopramide > 2-methyl-5-HT > sulpiride.
(3) At the agonal stage, the isoproterenol dose-response curve was shifted significantly to the right in myocardial membranes from endotoxic rats, but there was no significant decrease in maximum stimulated activity.
(4) Agonal state effects the stability of brain compounds and causes brain hypoxia.
(5) However, further studies showed compounds which exhibited either partial agonism in the RFA and competitive antagonism of 5-HT in the RA, or antagonism of 5-HT in both arteries with different affinities.
(6) Catecholamines were detectable in the major neurons, in small intensely fluorescent cells, and in adrenergic fibers with varicosities at levels that varied with the patient's age, cause of death, duration of the agonal period, the treatment administered, and the time when the material had been taken after death.
(7) Certain derivatives of the antagonists naloxone and naltrexone showed partial agonism.
(8) Except for desGly(NH2)AVP, which is a weak V2 agonist, the remaining desGly and desGly(NH2) analogues of 1-3 exhibit substantial V2 agonism and are thus highly selective V2 agonists.
(9) But bureaucratic dysfunction means less than half have been given out – as shown by two state department charts – and only at the end of agonizingly long waiting periods .
(10) The results failed to support the female agonism hypothesis and indicate a need for more detailed studies of intermale social dynamics.
(11) In the inferior parietal cortex, agonal status confounded this comparison.
(12) Dilevalol is a novel antihypertensive agent combining vasodilation due to selective beta 2-adrenergic receptor agonism with nonspecific beta antagonism.
(13) The results indicate that alpha 2-adrenergic agonism with clonidine inhibits the bronchoconstriction induced by histamine.
(14) We have found no evidence of a physiologically relevant effect of serotonin agonism on osmoregulated vasopressin release, or on the ability of normal man to excrete a water load.
(15) The partial agonism of N alpha-guanylhistamine is related to the ability of the drug to bind with the receptor in two different modes with similar affinity.
(16) In contrast U50,488H produced biphasic curves characterized by a higher potency phase of agonism that was susceptible to antagonism by 16-methylcyprenorphine (RX8008M) and a lower potency phase that was apparently non-opioid in nature.
(17) As this profile of activity is not shared by the shorter-acting compound, salbutamol, it would seem that anti-inflammatory activity is associated with beta-adrenoceptor agonism of long duration.
(18) To clarify the regulation of duodenal motility, the aim of the present study was to investigate the effects of alpha-adrenoceptor agonism and blockade and of galanin on duodenal motility.
(19) Agonist-independent pA2 estimates for ICS 205-930 (6.3-6.6) suggest a single site of agonism.
(20) In addition, analyses of beta-adrenoceptor agonism and antagonism, using selective (beta 1: T-1583, beta 2: procaterol) and non-selective (isoproterenol) agonists as well as selective (beta 1: atenolol, beta 2: ICI 118,551) and non-selective (propranolol) antagonists, confirmed that beta-adrenoceptors in the canine facial vein are not homogeneous, with the beta 1-subtype predominating over the beta 2-subtype, and that the canine saphenous vein has a homogeneous population of the beta 2-subtype, as reported in the other species.
Athletics
Definition:
(n.) The art of training by athletic exercises; the games and sports of athletes.
Example Sentences:
(1) Compared with conservative management, better long-term success (determined by return of athletic soundness and less evidence of degenerative joint disease) was achieved with surgical curettage of elbow subchondral cystic lesions.
(2) In a comparative study 11 athletes and 11 untrained students were investigated at rest, of these 6 trained and 5 untrained individuals during exercise as well.
(3) During recovery, while the heart rate decreased and the RR interval variance increased, there was a relative increase in LF and a relative decrease in HF in normal subjects (either sedentary or athletic).
(4) When allegations of systemic doping and cover-ups first emerged in the runup to the 2013 Russian world athletics championships, an IOC spokesman insisted: “Anti-doping measures in Russia have improved significantly over the last five years with an effective, efficient and new laboratory and equipment in Moscow.” London Olympics were sabotaged by Russia’s doping, report says Read more We now know that the head of that lauded Moscow lab, Grigory Rodchenko, admitted to intentionally destroying 1,417 samples in December last year shortly before Wada officials visited.
(5) "He's defined by being himself, by being smart, by being a good athlete," Goldwater said of Keller.
(6) "They haven't just got to be able to run like athletes," says Hall.
(7) #Tigers #Athletics @HunterFelt October 11, 2013 David Lengel (@LengelDavid) @HunterFelt Unless you're Yoenis Cespedes of course!
(8) The brightly lit ice palaces themselves are stunning, inside and out, and the sporting facilities have been rightly praised by almost all the athletes.
(9) However, the mean serum EPO concentrations of male and female athletes engaged in a variety of sports were not different from those of sedentary control subjects of both sexes (26.5-35.3 U.ml-1).
(10) Sudden death in healthy athletes is uncommon but, when it occurs, the primary mechanism is cardiovascular.
(11) Thus many athletes sustain dental-related injuries resulting in deformity and discomfort which may persist throughout their lives.
(12) He is big, strong, athletic, very quick and has got a fantastic leap on him," said McClaren.
(13) The increased volume of flowing blood and increased stroke volume in athletes probably allows for a reduction in flow velocity and thereby a reduction in kinetic energy.
(14) In Iten, I heard stories of athletes being told weeks in advance when to attend the testing centre in Eldoret.
(15) Many athletes, particularly female, are iron depleted, but true iron deficiencies are rare.
(16) Maximal power output was on average 81.1 W for the male population and varied from 65.8 W for class II athletes to 92.2 W for class LA.
(17) These results indicate that the increase in glucose storage by acute exercise is not systematically associated with an improved glucose homeostasis, suggesting that other adaptive mechanisms also contribute to the improvement of insulin sensitivity in endurance athletes.
(18) An echocardiographic evaluation of 77 members of a championship childhood swim team showed dimensional variations from normal in most athletes.
(19) Ballet dancers generated significantly less mechanical power than indoor soccer, basketball and bobsled athletes, while wrestlers generated significantly less power than indoor soccer and basketball athletes (all p less than 0.05).
(20) (GL) and M. deltoideus (D) were studied in 89 athletes practising 11 different sport events.