(1) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
(2) Under conditions of 5-HT1-like, 5-HT2 and 5-HT3 receptor blockade, the following rank order of agonism was observed: 5-HT > 5-methoxytryptamine = renzapride > (S)-zacopride > (R,S-zacopride > 5-carboxamidotryptamine > BRL 24682 > (R-zacopride > metoclopramide > 2-methyl-5-HT > sulpiride.
(3) At the agonal stage, the isoproterenol dose-response curve was shifted significantly to the right in myocardial membranes from endotoxic rats, but there was no significant decrease in maximum stimulated activity.
(4) Agonal state effects the stability of brain compounds and causes brain hypoxia.
(5) However, further studies showed compounds which exhibited either partial agonism in the RFA and competitive antagonism of 5-HT in the RA, or antagonism of 5-HT in both arteries with different affinities.
(6) Catecholamines were detectable in the major neurons, in small intensely fluorescent cells, and in adrenergic fibers with varicosities at levels that varied with the patient's age, cause of death, duration of the agonal period, the treatment administered, and the time when the material had been taken after death.
(7) Certain derivatives of the antagonists naloxone and naltrexone showed partial agonism.
(8) Except for desGly(NH2)AVP, which is a weak V2 agonist, the remaining desGly and desGly(NH2) analogues of 1-3 exhibit substantial V2 agonism and are thus highly selective V2 agonists.
(9) But bureaucratic dysfunction means less than half have been given out – as shown by two state department charts – and only at the end of agonizingly long waiting periods .
(10) The results failed to support the female agonism hypothesis and indicate a need for more detailed studies of intermale social dynamics.
(11) In the inferior parietal cortex, agonal status confounded this comparison.
(12) Dilevalol is a novel antihypertensive agent combining vasodilation due to selective beta 2-adrenergic receptor agonism with nonspecific beta antagonism.
(13) The results indicate that alpha 2-adrenergic agonism with clonidine inhibits the bronchoconstriction induced by histamine.
(14) We have found no evidence of a physiologically relevant effect of serotonin agonism on osmoregulated vasopressin release, or on the ability of normal man to excrete a water load.
(15) The partial agonism of N alpha-guanylhistamine is related to the ability of the drug to bind with the receptor in two different modes with similar affinity.
(16) In contrast U50,488H produced biphasic curves characterized by a higher potency phase of agonism that was susceptible to antagonism by 16-methylcyprenorphine (RX8008M) and a lower potency phase that was apparently non-opioid in nature.
(17) As this profile of activity is not shared by the shorter-acting compound, salbutamol, it would seem that anti-inflammatory activity is associated with beta-adrenoceptor agonism of long duration.
(18) To clarify the regulation of duodenal motility, the aim of the present study was to investigate the effects of alpha-adrenoceptor agonism and blockade and of galanin on duodenal motility.
(19) Agonist-independent pA2 estimates for ICS 205-930 (6.3-6.6) suggest a single site of agonism.
(20) In addition, analyses of beta-adrenoceptor agonism and antagonism, using selective (beta 1: T-1583, beta 2: procaterol) and non-selective (isoproterenol) agonists as well as selective (beta 1: atenolol, beta 2: ICI 118,551) and non-selective (propranolol) antagonists, confirmed that beta-adrenoceptors in the canine facial vein are not homogeneous, with the beta 1-subtype predominating over the beta 2-subtype, and that the canine saphenous vein has a homogeneous population of the beta 2-subtype, as reported in the other species.
Contest
Definition:
(v. t.) To make a subject of dispute, contention, litigation, or emulation; to contend for; to call in question; to controvert; to oppose; to dispute.
(v. t.) To strive earnestly to hold or maintain; to struggle to defend; as, the troops contested every inch of ground.
(v. t.) To make a subject of litigation; to defend, as a suit; to dispute or resist; as a claim, by course of law; to controvert.
(v. i.) To engage in contention, or emulation; to contend; to strive; to vie; to emulate; -- followed usually by with.
(n.) Earnest dispute; strife in argument; controversy; debate; altercation.
(n.) Earnest struggle for superiority, victory, defense, etc.; competition; emulation; strife in arms; conflict; combat; encounter.
Example Sentences:
(1) The size of Florida makes the kind of face-to-face politics of the earlier contests impossible, requiring instead huge ad spending.
(2) Since the election on 7 March there has been a bitter contest for power in Iraq led by Iran, Saudi Arabia and Turkey.
(3) It is understood that Cooper rejected pressure from senior Labour figures last week for both her and Liz Kendall to drop out and leave the way clear for Burnham to contest Corbyn alone.
(4) As he gears up to contest the Liberal Democrat seat of Gordon in north-east Scotland, Salmond effectively assumes a commanding role in the general election campaign.
(5) This is contested by the report of three cases of dilatation of Stensen's duct complicated by lithiasis and stenosis, with associated canalar pseudo-cysts.
(6) But in each party there are major issues to be dealt with as the primary phase of the contests slips gradually into the rear-view mirror.
(7) It was not just that there was only one female candidate – Berger – across four contests.
(8) Who's backing who in the Tory leadership contest The dramatic events have put May well in the lead in parliament, with the public backing of well over 100 MPs, including 10 cabinet ministers, followed by Leadsom, with just under 40 MPs, and then Michael Gove and Stephen Crabb with over 20.
(9) South Korea was put on high alert a year ago amid fears that the North was about to provoke a clash in the contested waters of the Yellow Sea.
(10) His formal entry into the contest marks a key moment in the nascent race for the Republican nomination, which is set to be the most congested presidential primary either party has held since 1976.
(11) 9.59am GMT Summary We’ll leave you with a summary of what transpired here throughout the day: • Julia Gillard announced a contest for her position as prime minister following calls by Simon Crean, a senior minister in her government, for her to be replaced by her predecessor, Kevin Rudd • Shortly before the ballot was to take place Kevin Rudd announced he would not stand for the Labor Party leadership , re-iterating his promise to the Australian people that he would not challenge Julia Gillard • When it came time for the ballot, Gillard was the only person who stood for the leadership and she and her deputy Wayne Swan were elected unopposed .
(12) Buhari has described himself as a “converted democrat” who repeatedly contested and lost elections after civilian rule was restored 16 years ago.
(13) This study analyzed the cost-effectiveness and distribution of costs by program stage of three smoking cessation programs: a smoking cessation class; an incentive-based quit smoking contest; and a self-help quit smoking kit.
(14) Jeremy Corbyn 'would increase mandate if he faced leadership contest' Read more Inside a ground floor hall, there are already no empty seats.
(15) The contours of the next Labour leadership contest are hard to see at the moment.
(16) The show is so out of touch that 17-year-old contestant Nicholas McDonald complained to Dermot live on air during week five that none of the genres had happened within his lifetime.
(17) José Mourinho ended this breathless contest on his knees with a sliding, turf-surfing celebration that was fuelled by relief as much as joy.
(18) Summer Zervos: Apprentice contestant claims Trump kissed and groped her Read more “There’s an old principle,” said William Galston , a former adviser to Bill Clinton and now a senior fellow at the Brookings Institution.
(19) Tonight the BBC's new singing contest The Voice goes head to head with Simon Cowell's Britain's Got Talent on ITV.
(20) Excretion of zinc and especially of silicon through the kidneys and intestine drastically grew on the day of the contest.