(1) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
(2) Under conditions of 5-HT1-like, 5-HT2 and 5-HT3 receptor blockade, the following rank order of agonism was observed: 5-HT > 5-methoxytryptamine = renzapride > (S)-zacopride > (R,S-zacopride > 5-carboxamidotryptamine > BRL 24682 > (R-zacopride > metoclopramide > 2-methyl-5-HT > sulpiride.
(3) At the agonal stage, the isoproterenol dose-response curve was shifted significantly to the right in myocardial membranes from endotoxic rats, but there was no significant decrease in maximum stimulated activity.
(4) Agonal state effects the stability of brain compounds and causes brain hypoxia.
(5) However, further studies showed compounds which exhibited either partial agonism in the RFA and competitive antagonism of 5-HT in the RA, or antagonism of 5-HT in both arteries with different affinities.
(6) Catecholamines were detectable in the major neurons, in small intensely fluorescent cells, and in adrenergic fibers with varicosities at levels that varied with the patient's age, cause of death, duration of the agonal period, the treatment administered, and the time when the material had been taken after death.
(7) Certain derivatives of the antagonists naloxone and naltrexone showed partial agonism.
(8) Except for desGly(NH2)AVP, which is a weak V2 agonist, the remaining desGly and desGly(NH2) analogues of 1-3 exhibit substantial V2 agonism and are thus highly selective V2 agonists.
(9) But bureaucratic dysfunction means less than half have been given out – as shown by two state department charts – and only at the end of agonizingly long waiting periods .
(10) The results failed to support the female agonism hypothesis and indicate a need for more detailed studies of intermale social dynamics.
(11) In the inferior parietal cortex, agonal status confounded this comparison.
(12) Dilevalol is a novel antihypertensive agent combining vasodilation due to selective beta 2-adrenergic receptor agonism with nonspecific beta antagonism.
(13) The results indicate that alpha 2-adrenergic agonism with clonidine inhibits the bronchoconstriction induced by histamine.
(14) We have found no evidence of a physiologically relevant effect of serotonin agonism on osmoregulated vasopressin release, or on the ability of normal man to excrete a water load.
(15) The partial agonism of N alpha-guanylhistamine is related to the ability of the drug to bind with the receptor in two different modes with similar affinity.
(16) In contrast U50,488H produced biphasic curves characterized by a higher potency phase of agonism that was susceptible to antagonism by 16-methylcyprenorphine (RX8008M) and a lower potency phase that was apparently non-opioid in nature.
(17) As this profile of activity is not shared by the shorter-acting compound, salbutamol, it would seem that anti-inflammatory activity is associated with beta-adrenoceptor agonism of long duration.
(18) To clarify the regulation of duodenal motility, the aim of the present study was to investigate the effects of alpha-adrenoceptor agonism and blockade and of galanin on duodenal motility.
(19) Agonist-independent pA2 estimates for ICS 205-930 (6.3-6.6) suggest a single site of agonism.
(20) In addition, analyses of beta-adrenoceptor agonism and antagonism, using selective (beta 1: T-1583, beta 2: procaterol) and non-selective (isoproterenol) agonists as well as selective (beta 1: atenolol, beta 2: ICI 118,551) and non-selective (propranolol) antagonists, confirmed that beta-adrenoceptors in the canine facial vein are not homogeneous, with the beta 1-subtype predominating over the beta 2-subtype, and that the canine saphenous vein has a homogeneous population of the beta 2-subtype, as reported in the other species.
Music
Definition:
(n.) The science and the art of tones, or musical sounds, i. e., sounds of higher or lower pitch, begotten of uniform and synchronous vibrations, as of a string at various degrees of tension; the science of harmonical tones which treats of the principles of harmony, or the properties, dependences, and relations of tones to each other; the art of combining tones in a manner to please the ear.
(n.) Melody; a rhythmical and otherwise agreeable succession of tones.
(n.) Harmony; an accordant combination of simultaneous tones.
(n.) The written and printed notation of a musical composition; the score.
(n.) Love of music; capacity of enjoying music.
(n.) A more or less musical sound made by many of the lower animals. See Stridulation.
Example Sentences:
(1) National policy on the longer-term future of the services will not be known until the government publishes a national music plan later this term.
(2) This week MediaGuardian 25, our survey of Britain's most important media companies, covering TV, radio, newspapers, magazines, music and digital, looks at BSkyB.
(3) Living by the "Big River" as a child, Cash soaked up work songs, church music, and country & western from radio station WMPS in Memphis, or the broadcasts from Nashville's Grand Ole Opry on Friday and Saturday evenings.
(4) Subjects' musical backgrounds were evaluated with a survey questionnaire.
(5) On raw music scores a sex-linked, time-of-day-induced priming effect was due to the prior presentation of CVs--that is, cognitive priming.
(6) Lady Gaga is not the first big music star to make a new album available early to mobile customers.
(7) He had links to networks including the Hammerskin Nation and was involved in an underground music scene often referred to as "white power music" or "hate rock".
(8) Strict fundamentalists oppose music in any form as a sensual distraction - the Taliban, of course, banned music in Afghanistan.
(9) Amplitude of the musical vibrations decreased by inhalation of amyl nitrite, but increased by infusion of methoxamine.
(10) While a clearcut relationship cannot be established between heavy metal music and destructive behavior, evidence shows that such music promotes and supports patterns of drug abuse, promiscuous sexual activity, and violence.
(11) For Burroughs, who had been publishing ground-breaking books for 20 years without much appreciable financial return, it was association with fame and the music industry, as well as the possible benefits: a wider readership, film hook-ups and more money.
(12) Much of the week's music isn't actually sanctioned by the festival, with evenings hosted by blogs, brands, magazines, labels and, for some reason, Cirque du Soleil .
(13) The musical would begin previews in Chicago on December 21, and move to Broadway in February.
(14) His coding talent attracted attention early: a music-recommendation program he wrote as a teenager brought approaches from both Microsoft and AOL.
(15) Thanks to the groundbreaking technology and heavy investment of a new breed of entertainment retailers offering access services, we are witnessing a revolution in the entertainment industry, benefitting consumers, creators and content owners alike.” ERA acts as a forum for the physical and digital retail sectors of music, and represents over 90% of the of the UK’s entertainment retail market.
(16) In film, music videos and TV shows, especially those traditionally consumed by a young demographic, we are used to seeing women stripping and frolicking with one another.
(17) If we’ve a duty to pass folk music on, we should also bring it up to date and make it relevant to our times,” he says.
(18) Changes to the Mac Pro desktop computer are also expected, as is a new music streaming service .
(19) "What this proves is that the way Bowie engineered his comeback was a stroke of genius," said music writer Simon Price.
(20) Was that misreading the mood music of the referendum?” He claimed that many Tories had expressed their anger directly to Rudd about the controversial policy, which has since been watered down.