(1) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
(2) Under conditions of 5-HT1-like, 5-HT2 and 5-HT3 receptor blockade, the following rank order of agonism was observed: 5-HT > 5-methoxytryptamine = renzapride > (S)-zacopride > (R,S-zacopride > 5-carboxamidotryptamine > BRL 24682 > (R-zacopride > metoclopramide > 2-methyl-5-HT > sulpiride.
(3) At the agonal stage, the isoproterenol dose-response curve was shifted significantly to the right in myocardial membranes from endotoxic rats, but there was no significant decrease in maximum stimulated activity.
(4) Agonal state effects the stability of brain compounds and causes brain hypoxia.
(5) However, further studies showed compounds which exhibited either partial agonism in the RFA and competitive antagonism of 5-HT in the RA, or antagonism of 5-HT in both arteries with different affinities.
(6) Catecholamines were detectable in the major neurons, in small intensely fluorescent cells, and in adrenergic fibers with varicosities at levels that varied with the patient's age, cause of death, duration of the agonal period, the treatment administered, and the time when the material had been taken after death.
(7) Certain derivatives of the antagonists naloxone and naltrexone showed partial agonism.
(8) Except for desGly(NH2)AVP, which is a weak V2 agonist, the remaining desGly and desGly(NH2) analogues of 1-3 exhibit substantial V2 agonism and are thus highly selective V2 agonists.
(9) But bureaucratic dysfunction means less than half have been given out – as shown by two state department charts – and only at the end of agonizingly long waiting periods .
(10) The results failed to support the female agonism hypothesis and indicate a need for more detailed studies of intermale social dynamics.
(11) In the inferior parietal cortex, agonal status confounded this comparison.
(12) Dilevalol is a novel antihypertensive agent combining vasodilation due to selective beta 2-adrenergic receptor agonism with nonspecific beta antagonism.
(13) The results indicate that alpha 2-adrenergic agonism with clonidine inhibits the bronchoconstriction induced by histamine.
(14) We have found no evidence of a physiologically relevant effect of serotonin agonism on osmoregulated vasopressin release, or on the ability of normal man to excrete a water load.
(15) The partial agonism of N alpha-guanylhistamine is related to the ability of the drug to bind with the receptor in two different modes with similar affinity.
(16) In contrast U50,488H produced biphasic curves characterized by a higher potency phase of agonism that was susceptible to antagonism by 16-methylcyprenorphine (RX8008M) and a lower potency phase that was apparently non-opioid in nature.
(17) As this profile of activity is not shared by the shorter-acting compound, salbutamol, it would seem that anti-inflammatory activity is associated with beta-adrenoceptor agonism of long duration.
(18) To clarify the regulation of duodenal motility, the aim of the present study was to investigate the effects of alpha-adrenoceptor agonism and blockade and of galanin on duodenal motility.
(19) Agonist-independent pA2 estimates for ICS 205-930 (6.3-6.6) suggest a single site of agonism.
(20) In addition, analyses of beta-adrenoceptor agonism and antagonism, using selective (beta 1: T-1583, beta 2: procaterol) and non-selective (isoproterenol) agonists as well as selective (beta 1: atenolol, beta 2: ICI 118,551) and non-selective (propranolol) antagonists, confirmed that beta-adrenoceptors in the canine facial vein are not homogeneous, with the beta 1-subtype predominating over the beta 2-subtype, and that the canine saphenous vein has a homogeneous population of the beta 2-subtype, as reported in the other species.
Victorian
Definition:
(a.) Of or pertaining to the reign of Queen Victoria of England; as, the Victorian poets.
Example Sentences:
(1) In north Wales, Llandudno town council has had to cancel its annual display at short notice after it was told it would have to pay at least £22,000 to insure the wonderful Victorian pier in case of a fire.
(2) In the worst cases, they are the 21st-century equivalent of the desperate dawn queue at the Victorian factory gate.
(3) The prevalence of past infection with hepatitis B virus in health care personnel was investigated by questionnaire and by a serological survey of personnel in a representative selection of Victorian hospitals and institutions.
(4) Friends says Cameron has no wish to take Britain back to a Victorian values "back to basics" agenda.
(5) In contrast to the aggressive capitalism of the US, for example, he observed that in spite of the Victorian boom: “England did not become a business society ...
(6) Rather than his extensive musings on art and politics, Morris is perhaps better known for his wallpaper and fabric designs of the late Victorian period.
(7) Victoria published its school funding heads of agreement in early August, and a Victorian government spokeswoman said this week it considered that binding.
(8) Ian Hislop’s Victorian Benefits airs on 7 April on BBC2.
(9) On the information available to me all relevant matters were dealt with in compliance with commonwealth law and to the satisfaction of the Australian Electoral Commission.” “The Liberal party regarded working papers and process issues as internal matters between it and the AEC.” The Victorian Nationals and the NT Country Liberals did not respond to requests for comment.
(10) Mike Ashley running Sports Direct like 'Victorian workhouse' Read more I find the fact that the majority of workers at Shirebrook are agency staff troubling.
(11) An audit of the interval cases of cervical cancer that had been diagnosed within 36 months of a smear having been reported as negative by the Victorian Cytology Gynaecological Service among women registered with cervical cancer during 1982-6.
(12) I act with deeds and words, because the government seems determined to resurrect the old Victorian approach to disabled people.
(13) "We inherited a crumbling infrastructure, starved of funding; Victorian schools with rundown gyms, and thousands of playing fields sold off," Sutcliffe said.
(14) The local undertakers were pleased to discover the great Henty to be the man they had always imagined - a full-bearded giant, stern and wise, dressed like a warrior hero or - much the same thing - a Victorian gentleman with the whiff of gunpowder and the clash of sabres about him.
(15) The rather small amount of semen the man ejaculates suggests he is a frequent masturbator.” To my surprise, I sense there is some nobility in Gerald’s enterprise and I recall a book written by a professor who is not quite so brilliant as me, in which Victorian sexual activity was explored through the prism of voyeurism.
(16) The fall took place at a three-storey Victorian house in Herne Hill, near Brixton, where the group are believed to have lived for about seven years from 1997.
(17) While the opening tranche of "tales" derive from the work of forgotten contemporary humorists, the pieces of London reportage that he began to contribute to the Morning Chronicle in autumn 1834 ("Gin Shops", "Shabby-Genteel People", "The Pawnbroker's Shop") are like nothing else in pre-Victorian journalism: bantering and hard-headed by turns, hectic and profuse, falling over themselves to convey every last detail of the metropolitan front-line from which Dickens sent back his dispatches.
(18) While Victorians celebrated the empire on which the sun would never set with successive jubilees (golden, 1887, and diamond, 1897), many readers fretted over foreign (increasingly German) threats to the harmony of English life.
(19) Origin Energy , which owns Australia’s largest power station, Eraring, has proposed a progressive phase-out of brown coal generation in response to a Victorian government review of climate policy.
(20) The AWU’s Victorian branch secretary, Ben Davis, ordered the correction in February 2015.