(1) alpha 1-Adrenergic agonists, phenylephrine and norfenefrine, did not affect the synthesis.
(2) Data obtained with fenoldopam were corroborated with use of SK&F 38393, another dopamine D1-receptor agonist.
(3) The GABA receptor agonist progabide reduced VCMs and locomotor activity.
(4) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(5) Exposure to nanomolar concentrations of saralasin, an Ang II agonist, attenuated the passage of the fluorophores across the monolayers by 50-75%.
(6) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(7) The binding to DNA-cellulose of heat-activated [3H]RU486-receptor complexes was slightly decreased (37%) when compared with that of the agonist [3H]R5020-receptor complexes (47%).
(8) These later results suggest that dopamine agonists increase sensorimotor reactivity measured with acoustic startle by acting on sensory rather than motor parts of the reflex arc.
(9) Only methoxyindole acetic acid was detectable after incubation of unstimulated and alpha-adrenergic-agonist-treated pineal glands.
(10) It inhibits platelet and vascular smooth muscle activation by cGMP-dependent attenuation of the agonist-induced rise of intracellular free Ca2+.
(11) The elimination half-life of most beta-agonists is relatively short, and pharmacokinetics are independent of dose and duration of treatment.
(12) Substance P (SP), a relatively non-selective tachykinin receptor agonist, and Septide and Senktide, highly selective NK-1 and NK-3 tachykinin receptor agonists, respectively, were injected intradermally in rats.
(13) Responses of control tissues to an alpha agonist (norepinephrine) were increased at lower temperatures and responses to a beta agonist (isoprenaline) were increased at higher temperatures.
(14) The inhibition of all three agonist responses by 1.1 mM calcium was competitive.
(15) The alpha 2 agonist, clonidine, produced a larger dose-related increase in food intake in lean rats than in the fatty rats.
(16) This stimulation is mediated by one receptor with an apparent affinity of 3.3 X 10(-6) M. The hydroxyl group in the para position on phenylethanolamine was absolutely necessary to obtain an agonist whereas the meta hydroxyl group or the presence of a catechol almost suppressed the activity.
(17) The alpha 2-adrenoceptor agonist clonidine is most potent for stimulating Isc.
(18) Moreover, the ribosylation inhibitors converted the glucocorticoid antagonist RU-486 into a potent agonist for cytolysis of L1210 cells.
(19) We have characterized the effects of adenosine, the A1-receptor agonist N6-(L-2-phenylisopropyl)-adenosine (PIA) and the A2-receptor agonist 5'-(N-ethyl)-carboxamido-adenosine (NECA), in isolated human pulmonary vessels.
(20) Long-term treatment with agents that stimulate the beta-receptor (prenalterol and pirbuterol) has not proved to be useful in the treatment of chronic heart failure; moreover, prolonged treatment with beta-agonists (dobutamine and pirbuterol) may adversely affect survival.
Combative
Definition:
(a.) Disposed to engage in combat; pugnacious.
Example Sentences:
(1) I want to be clear; the American forces that have been deployed to Iraq do not and will not have a combat mission,” said Obama in a speech to troops at US Central Command headquarters in Florida.
(2) The manufacturers, British Aerospace describe it as a "single-seat, radar equipped, lightweight, multi-role combat aircraft, providing comprehensive air defence and ground attack capability".
(3) Infusion of sodium lactate associated with isoproterenol could be used to combat the depressent effects of betablockers in patients with cardiac disorders.
(4) By the time Van Kirk returned to the US in June 1943, he had flown 58 combat and eight transport missions.
(5) They insist this is the best way of ensuring the country does not descend into chaos before the final withdrawal of combat troops.
(6) That’s a criticism echoed by Democrats in the Senate, who issued a report earlier this month criticising Republicans for passing sweeping legislation in July to combat addiction , the Comprehensive Addiction and Recovery Act (Cara), but refusing to fund it.
(7) They are the E-1 to E-3 pay grades and soldiers in combat arms units.
(8) We reviewed the pre-Vietnam contents of the service medical and personnel records of 250 Vietnam combat veterans, in an attempt to identify factors predisposing to the development of posttraumatic stress disorder (PTSD).
(9) If we reach the point where I believe our advisers should accompany Iraqi troops on attacks against specific [Isis] targets, I will recommend that to the president,” Dempsey said, preferring the term “close combat advising”.
(10) Environmental campaigners had been apprehensive about the chances of the Senate ratifying a new international treaty – a successor to the Kyoto protocol – to combat global warming unless a consensus had already been reached on Capitol Hill.
(11) Germany’s parliament has thrown its weight behind the European campaign against Islamic State , voting with a solid majority in favour of deploying military personnel to Syria in a non-combat role.
(12) The Pentagon leadership suggested to a Senate panel on Tuesday that US ground troops may directly join Iraqi forces in combat against the Islamic State (Isis), despite US president Barack Obama’s repeated public assurances against US ground combat in the latest Middle Eastern war.
(13) In government, Abbott had relished the daily combat but his officials complained he wasn’t enamoured by detailed policy work.
(14) The home fans were lifted by the sight of Billy Bonds, a legend in these parts, being presented with a lifetime achievement award before the kick-off and the former West Ham captain and manager probably would have enjoyed playing in Allardyce's combative midfield.
(15) Rarely has there been a potential presidential candidate so battle-hardened and ready for combat.
(16) Computer says no: Amazon uses AI to combat fake reviews Read more “Imagine as the CEO of a major company you go off and spend £100m on gathering data,” Hammond says.
(17) Al-Shamiri has been held as an enemy combatant without charge at Guantánamo since 2002.
(18) The government's decision to allow a cull of badgers, reportedly to combat bovine tuberculosis, "flies in the face of the scientific evidence" and will serve only to spread the disease, Labour claims.
(19) In addition, multiple regression analysis was used to examine predictive relationships between premilitary adjustment, military adjustment, combat exposure, and post-traumatic stress disorder (PTSD).
(20) The prime minister could publish the reply upon his return from the opening of climate change talks in Paris on Tuesday next week, depending on the progress made in discussions between Russia and the west on the best approach to combating Isis.