(1) alpha 1-Adrenergic agonists, phenylephrine and norfenefrine, did not affect the synthesis.
(2) Data obtained with fenoldopam were corroborated with use of SK&F 38393, another dopamine D1-receptor agonist.
(3) The GABA receptor agonist progabide reduced VCMs and locomotor activity.
(4) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(5) Exposure to nanomolar concentrations of saralasin, an Ang II agonist, attenuated the passage of the fluorophores across the monolayers by 50-75%.
(6) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(7) The binding to DNA-cellulose of heat-activated [3H]RU486-receptor complexes was slightly decreased (37%) when compared with that of the agonist [3H]R5020-receptor complexes (47%).
(8) These later results suggest that dopamine agonists increase sensorimotor reactivity measured with acoustic startle by acting on sensory rather than motor parts of the reflex arc.
(9) Only methoxyindole acetic acid was detectable after incubation of unstimulated and alpha-adrenergic-agonist-treated pineal glands.
(10) It inhibits platelet and vascular smooth muscle activation by cGMP-dependent attenuation of the agonist-induced rise of intracellular free Ca2+.
(11) The elimination half-life of most beta-agonists is relatively short, and pharmacokinetics are independent of dose and duration of treatment.
(12) Substance P (SP), a relatively non-selective tachykinin receptor agonist, and Septide and Senktide, highly selective NK-1 and NK-3 tachykinin receptor agonists, respectively, were injected intradermally in rats.
(13) Responses of control tissues to an alpha agonist (norepinephrine) were increased at lower temperatures and responses to a beta agonist (isoprenaline) were increased at higher temperatures.
(14) The inhibition of all three agonist responses by 1.1 mM calcium was competitive.
(15) The alpha 2 agonist, clonidine, produced a larger dose-related increase in food intake in lean rats than in the fatty rats.
(16) This stimulation is mediated by one receptor with an apparent affinity of 3.3 X 10(-6) M. The hydroxyl group in the para position on phenylethanolamine was absolutely necessary to obtain an agonist whereas the meta hydroxyl group or the presence of a catechol almost suppressed the activity.
(17) The alpha 2-adrenoceptor agonist clonidine is most potent for stimulating Isc.
(18) Moreover, the ribosylation inhibitors converted the glucocorticoid antagonist RU-486 into a potent agonist for cytolysis of L1210 cells.
(19) We have characterized the effects of adenosine, the A1-receptor agonist N6-(L-2-phenylisopropyl)-adenosine (PIA) and the A2-receptor agonist 5'-(N-ethyl)-carboxamido-adenosine (NECA), in isolated human pulmonary vessels.
(20) Long-term treatment with agents that stimulate the beta-receptor (prenalterol and pirbuterol) has not proved to be useful in the treatment of chronic heart failure; moreover, prolonged treatment with beta-agonists (dobutamine and pirbuterol) may adversely affect survival.
Conflict
Definition:
(v.) A striking or dashing together; violent collision; as, a conflict of elements or waves.
(v.) A strife for the mastery; hostile contest; battle; struggle; fighting.
(v. i.) To strike or dash together; to meet in violent collision; to collide.
(v. i.) To maintain a conflict; to contend; to engage in strife or opposition; to struggle.
(v. i.) To be in opposition; to be contradictory.
Example Sentences:
(1) Acceptance of less than ideal donors is ill-advised even though rejection of such donors conflicts with the current shortage of organs.
(2) The effects of glucagon-induced insulin secretion upon this lipid regulation are discussed that may resolve conflicting reports in the literature are resolved.
(3) With respect to family environment, a history of sexual abuse was associated with perceptions that families of origin had less cohesion, more conflict, less emphasis on moral-religious matters, less emphasis on achievement, and less of an orientation towards intellectual, cultural, and recreational pursuits.
(4) There is, however, conflicting evidence as to whether squamous cell NPCs are also EBV-associated.
(5) They are just literally lying.” In August Microsoft severed its ties, saying Alec’s stance on climate change and several other issues “conflicted directly with Microsoft’s values”.
(6) Nearly four months into the conflict, rebels control large parts of eastern Libya , the coastal city of Misrata, and a string of towns in the western mountains, near the border with Tunisia.
(7) Following the hypothesis that infertile patients may present emotional conflicts with regard to the wish of having a child, psychodynamic interviews were carried out with 116 infertile couples concomitantly with their first consultation at the Sterility Department.
(8) Why is it so surprising to people that a boy like Chol, just out of conflict, has thought through the needs of his country in such a detailed way?” While Beah’s zeal is laudable, the situation in South Sudan is dire .
(9) Some aspects of the life structure, of course, are also unconscious, namely, those having to do with attempted solutions to core personality conflicts and those reflecting modes of ego functioning.
(10) Although individual IRB chairpersons and oncology investigators may have important differences of opinion concerning the ethics of phase I trials, these disagreements do not represent a widespread area of ethical conflict in clinical research.
(11) Conflicting reports exist on the postprandial response of serum cationic trypsin like immunoreactivity (SCTLI).
(12) Technically speaking, this modality of brief psychotherapy is based on the nonuse of transferential interpretations, on impeding the regression od the patient, on facilitating a cognitice-affective development of his conflicts and thus obtain an internal object mutation which allows the transformation of the "past" into true history, and the "present" into vital perspectives.
(13) Many organisations choose not to affiliate their aid work with the UN, particularly in conflict situations, where the organisation is not always seen either as neutral or separate from the work of the UN security council.
(14) The al-Shifa, like hospitals across Gaza, is chronically short of medical supplies after treating thousands of wounded during the conflict.
(15) "This will obviously be a sensitive topic for the US administration, but partners in the transatlantic alliance must be clear on common rules of engagement in times of conflict if we are to retain any moral standing in the world," Verhofstadt said.
(16) There is a clear conflict between the economics, society and the politics, the immediate versus the long term.
(17) These apparent conflicting results between IK and the tail current could not be explained by extracellular K+ fluctuation, because 20 mM Cs+ alone depressed both factors, but an additional application of Ba2+ caused an increase in both components compared with those in the former condition.
(18) The UN estimates that at least 10 million people in east Africa will be in need of humanitarian assistance as a result of severe food shortages, failed harvest, rising food prices and conflict in the region.
(19) (1) EXCP appears to be a more serious finding only in those higher risk individuals with either a positive EXECG or lower MAXRPP; (2) EXCP and its interactions may help discriminate between anginal and nonanginal, exertional chest pain, and (3) the contradictory results found when EXCP was allowed to interact may explain conflicting results in previous multivariate models regarding the predictive significance of EXCP.
(20) The Nigerian government has been heavily criticised for failing to protect civilians in an increasingly violent conflict that left about 10,000 dead last year.