(a.) Pertaining to violent contests, bodily or mental; pertaining to athletic or polemic feats; athletic; combative; hence, strained; unnatural.
Example Sentences:
(1) alpha 1-Adrenergic agonists, phenylephrine and norfenefrine, did not affect the synthesis.
(2) Data obtained with fenoldopam were corroborated with use of SK&F 38393, another dopamine D1-receptor agonist.
(3) The GABA receptor agonist progabide reduced VCMs and locomotor activity.
(4) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(5) Exposure to nanomolar concentrations of saralasin, an Ang II agonist, attenuated the passage of the fluorophores across the monolayers by 50-75%.
(6) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(7) The binding to DNA-cellulose of heat-activated [3H]RU486-receptor complexes was slightly decreased (37%) when compared with that of the agonist [3H]R5020-receptor complexes (47%).
(8) These later results suggest that dopamine agonists increase sensorimotor reactivity measured with acoustic startle by acting on sensory rather than motor parts of the reflex arc.
(9) Only methoxyindole acetic acid was detectable after incubation of unstimulated and alpha-adrenergic-agonist-treated pineal glands.
(10) It inhibits platelet and vascular smooth muscle activation by cGMP-dependent attenuation of the agonist-induced rise of intracellular free Ca2+.
(11) The elimination half-life of most beta-agonists is relatively short, and pharmacokinetics are independent of dose and duration of treatment.
(12) Substance P (SP), a relatively non-selective tachykinin receptor agonist, and Septide and Senktide, highly selective NK-1 and NK-3 tachykinin receptor agonists, respectively, were injected intradermally in rats.
(13) Responses of control tissues to an alpha agonist (norepinephrine) were increased at lower temperatures and responses to a beta agonist (isoprenaline) were increased at higher temperatures.
(14) The inhibition of all three agonist responses by 1.1 mM calcium was competitive.
(15) The alpha 2 agonist, clonidine, produced a larger dose-related increase in food intake in lean rats than in the fatty rats.
(16) This stimulation is mediated by one receptor with an apparent affinity of 3.3 X 10(-6) M. The hydroxyl group in the para position on phenylethanolamine was absolutely necessary to obtain an agonist whereas the meta hydroxyl group or the presence of a catechol almost suppressed the activity.
(17) The alpha 2-adrenoceptor agonist clonidine is most potent for stimulating Isc.
(18) Moreover, the ribosylation inhibitors converted the glucocorticoid antagonist RU-486 into a potent agonist for cytolysis of L1210 cells.
(19) We have characterized the effects of adenosine, the A1-receptor agonist N6-(L-2-phenylisopropyl)-adenosine (PIA) and the A2-receptor agonist 5'-(N-ethyl)-carboxamido-adenosine (NECA), in isolated human pulmonary vessels.
(20) Long-term treatment with agents that stimulate the beta-receptor (prenalterol and pirbuterol) has not proved to be useful in the treatment of chronic heart failure; moreover, prolonged treatment with beta-agonists (dobutamine and pirbuterol) may adversely affect survival.
Contrived
Definition:
(imp. & p. p.) of Contrive
Example Sentences:
(1) "If there is some kind of contrived scheme or vehicle, ie it's obvious that the purpose of the scheme is to avoid paying VAT and it's taking advantage of a loophole and we consider that tax is actually owed on the scheme, rather than just being a case of sensible tax planning … we can make the judgment that this is not legitimate tax planning.
(2) Here they led within 90 seconds against a team whose fragility has been all too clear this term, and still contrived to wilt almost apologetically.
(3) And I'll be catching several buzzy acts who I contrived to miss last year – Ivo Graham, Ursula Burns, Trygve (Squidboy) Wakenshaw, Phil Wang, Paul Currie.
(4) Rafael Benítez must contrive a way of picking this team up, as well as a starting lineup who are relatively fresh for Elland Road and a cup tie that once would have stirred the senses.
(5) When Grayson remarks to the men he meets that his transvestism allows him enough distance from maleness to view it as an observer, rather than bristle they nod, quietly ponder for a moment and then step back themselves, apparently accepting that maleness is such a weird contrivance that to look at it with critical eyes is Not Even A Thing.
(6) Capello's men have contrived to fail more severely than the line‑up beaten 4-2 by Uruguay in 1954.
(7) Support is provided by intercostal angiography, and by observations upon normal anatomy, the pathological anatomy of mature scoliotic spines and the anatomy of contrived scoliosis in normal spines.
(8) The natural and the contrived social experiments are reviewed as well as the issue of needed research on the effects of regulation on science and on the protection of privacy.
(9) Even after the Daily Mail's Jack Tinker (obituary, October 29 1996) contrived for Shulman's career as a theatre critic to be brought to an end in 1991, he continued to write a column for the Evening Standard on art affairs - until he was 83.
(10) Some patients find that the risk of a spontaneous attack is lessened following a self-induced seizure and can therefore contrive their fits to occur only in situations which are safe and convenient.
(11) Some contrivances in anastomosing a conduit were also proposed to achieve an excellent result.
(12) "It's more contrived in terms of 'good girl gone bad' or 'I'm so edgy – I'm twerking in this context.'
(13) Always a contrived fiction, this sequence juxtaposes a poignant fantasy of a fully fit presenter with the merciless world of hard news.
(14) A coded panel of 100 contrived dried blood spots prepared form well characterised anti-HIV-1 and anti-HIV-2 positive sera and an anti-HIV negative serum was distributed to eight testing centres.
(15) Despite papal fiction being such a crowded church, Harris, in Conclave , contrives a twist involving the number of cardinal-electors that seems to me completely new, showing that the genre still has possibilities.
(16) Although oral administration volume is limited in small animal model, enhancing its antitumor effect may be possible in clinical application by contriving the method of administration.
(17) Events went from bad to ridiculous for the Redbirds in the second inning, when Stephen Drew popped the ball up into the infield and catcher Yadier Molina and pitcher Adam Wainwright both moved towards the ball and then contrived to call each other off and watched the ball drop harmlessly between them.
(18) "We will dedicate our seventh goal to our wives, and the eighth to our dogs," quipped one player, while the manager, Jupp Derwall, promised that if his team contrived to lose he would "jump on the first train back to Munich".
(19) The tasks were presented in various ways: by means of a table-top simulation on which traffic scenarios had been contrived; by means of photographs of road situations; and by taking the children to real-world sites in the streets near their schools.
(20) The amendment left the government facing the prospect of scuttling its own legislation to give the tax office greater powers to stop global companies using “artificial or contrived arrangements” to avoid tax obligations.