What's the difference between agonized and vicious?
Agonized
Definition:
(imp. & p. p.) of Agonize
Example Sentences:
(1) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
(2) Under conditions of 5-HT1-like, 5-HT2 and 5-HT3 receptor blockade, the following rank order of agonism was observed: 5-HT > 5-methoxytryptamine = renzapride > (S)-zacopride > (R,S-zacopride > 5-carboxamidotryptamine > BRL 24682 > (R-zacopride > metoclopramide > 2-methyl-5-HT > sulpiride.
(3) At the agonal stage, the isoproterenol dose-response curve was shifted significantly to the right in myocardial membranes from endotoxic rats, but there was no significant decrease in maximum stimulated activity.
(4) Agonal state effects the stability of brain compounds and causes brain hypoxia.
(5) However, further studies showed compounds which exhibited either partial agonism in the RFA and competitive antagonism of 5-HT in the RA, or antagonism of 5-HT in both arteries with different affinities.
(6) Catecholamines were detectable in the major neurons, in small intensely fluorescent cells, and in adrenergic fibers with varicosities at levels that varied with the patient's age, cause of death, duration of the agonal period, the treatment administered, and the time when the material had been taken after death.
(7) Certain derivatives of the antagonists naloxone and naltrexone showed partial agonism.
(8) Except for desGly(NH2)AVP, which is a weak V2 agonist, the remaining desGly and desGly(NH2) analogues of 1-3 exhibit substantial V2 agonism and are thus highly selective V2 agonists.
(9) But bureaucratic dysfunction means less than half have been given out – as shown by two state department charts – and only at the end of agonizingly long waiting periods .
(10) The results failed to support the female agonism hypothesis and indicate a need for more detailed studies of intermale social dynamics.
(11) In the inferior parietal cortex, agonal status confounded this comparison.
(12) Dilevalol is a novel antihypertensive agent combining vasodilation due to selective beta 2-adrenergic receptor agonism with nonspecific beta antagonism.
(13) The results indicate that alpha 2-adrenergic agonism with clonidine inhibits the bronchoconstriction induced by histamine.
(14) We have found no evidence of a physiologically relevant effect of serotonin agonism on osmoregulated vasopressin release, or on the ability of normal man to excrete a water load.
(15) The partial agonism of N alpha-guanylhistamine is related to the ability of the drug to bind with the receptor in two different modes with similar affinity.
(16) In contrast U50,488H produced biphasic curves characterized by a higher potency phase of agonism that was susceptible to antagonism by 16-methylcyprenorphine (RX8008M) and a lower potency phase that was apparently non-opioid in nature.
(17) As this profile of activity is not shared by the shorter-acting compound, salbutamol, it would seem that anti-inflammatory activity is associated with beta-adrenoceptor agonism of long duration.
(18) To clarify the regulation of duodenal motility, the aim of the present study was to investigate the effects of alpha-adrenoceptor agonism and blockade and of galanin on duodenal motility.
(19) Agonist-independent pA2 estimates for ICS 205-930 (6.3-6.6) suggest a single site of agonism.
(20) In addition, analyses of beta-adrenoceptor agonism and antagonism, using selective (beta 1: T-1583, beta 2: procaterol) and non-selective (isoproterenol) agonists as well as selective (beta 1: atenolol, beta 2: ICI 118,551) and non-selective (propranolol) antagonists, confirmed that beta-adrenoceptors in the canine facial vein are not homogeneous, with the beta 1-subtype predominating over the beta 2-subtype, and that the canine saphenous vein has a homogeneous population of the beta 2-subtype, as reported in the other species.
Vicious
Definition:
(a.) Characterized by vice or defects; defective; faulty; imperfect.
(a.) Addicted to vice; corrupt in principles or conduct; depraved; wicked; as, vicious children; vicious examples; vicious conduct.
(a.) Not correct or pure; corrupt; as, vicious language; vicious idioms.
(a.) Not well tamed or broken; given to bad tricks; unruly; refractory; as, a vicious horse.
(a.) Bitter; spiteful; malignant.
Example Sentences:
(1) Los Angeles were relentless in their vicious pursuit of a game-tying goal on Wednesday, bidding to send Game 4 into overtime.
(2) But when in mid-October two of the artists received death threats, the menaces were widely reported and rekindled debate, prompting vicious, anti-Muslim comments on Danish talk shows.
(3) When he attacked New York, his vicious crusade was as much against skyscrapers as it was against western values and the US.
(4) A vicious feud playing out within Uzbekistan's ruling family took a new twist on Monday , when prosecutors announced that the clan's most flamboyant member faces charges of involvement in mafia-style corruption.
(5) This was evident just this week when, as an example, a young woman in San Francisco was viciously killed by a five-time deported Mexican with a long criminal record, who was forced back into the United States because they didn’t want him in Mexico.
(6) Each of these reactions can increase the perception of chest pain, contributing to a vicious cycle that exacerbates both the chest pain and the anxiety.
(7) This vicious circle should be broken rather by finding optimal conditions than by a middle course determined by experimental requirements, economical frames and general notions about what may be good for the animal.
(8) In spite of the relatively large sample and the given number of variables the problem of the vicious circle might occur.
(9) Recent data are cited for the proposition that these changes constitute a closed pathogenetic concatenation creating a vicious circle.
(10) When there is upheaval within China’s own borders – riots, protests, vicious political power struggles – hardly a sniff of it will be found in the pages of the country’s heavily-controlled press.
(11) According to the International Crisis Group , tensions within and between the two major political parties, competing claims to the presidency between northern and Niger Delta politicians and along religious lines, along with inadequate preparations by the electoral commission and apparent bias by security agencies, suggest the country is heading toward a volatile and vicious electoral contest.
(12) A vicious circle with the increased resistance as the key factor can be identified.
(13) This vicious cycle could be interrupted by segmental epidural anesthesia with procaine as well as by blockade of sympathoexcitation at the central nervous level with clonidine in anesthetized dogs.
(14) This is in stark comparison to the gruesome, vicious suffering that he inflicted on his two victims – and the lifetime of suffering he has caused their family.” Wood was executed for shooting to death Debra Dietz, his former girlfriend, and her father, Eugene Dietz, in Tucson in 1989.
(15) Spicer, who so viciously attacked the press on Saturday, had to hurriedly walk back the comments of his boss when Trump, during an interview with the Washington Post before the inauguration, promised “insurance for everybody”.
(16) Using mathematical models of the population dynamics of T helper cells, HIV and other pathogens we address three facets of the interactions between HIV and other pathogens: enhanced HIV replication due to immune stimulation by other pathogens; modified immune control of other pathogens due to immunosuppression by HIV; and the vicious circle formed by positive feedback between these two effects.
(17) Since the initially peaceful demonstrations against his regime began more than three years ago, he has proved himself, by turns, foolish, craven and vicious.
(18) He said US prisons were tough and safe enough to handle the most vicious al-Qaida terrorist suspects now held at Guantánamo.
(19) When Cruise announced last October that he was suing Bauer, his lawyer, Bert Fields, described the claim that the actor had deserted his daughter as a “vicious lie”.
(20) Meanwhile, people in poor countries are already battling its vicious storms.