(1) Total cellular proteins from the livers of 4-, 16- and 52-week-old hepatitis- and hepatoma-predisposed Long-Evans Cinnamon (LEC) rats were compared to those from the livers of the corresponding control rats [Long-Evans Agouti (LEA) rats] by two-dimensional gel electrophoresis.
(2) Nonagouti rats were significantly easier to approach, capture, and handle than their agouti sibs.
(3) We have characterized a gene encoding a novel 131 amino acid protein that we propose is the one gene associated with the agouti locus.
(4) The cortical representation of the contralateral visual field in area 17 of the agouti's brain was studied by multiunit recording.
(5) Future experiments will determine the type of protein(s) encoded by the agouti coat color locus and establish the mechanism by which these protein(s) control the nature and timing of pigment production by melanocytes in the hair follicle.
(6) In a preliminary study, different rates of N-, O- and N,O- demethylation of dextromethorphan to yield D-methoxymorphinane, dextrorphan and D-hydroxymorphinane, respectively, were found in extensive- (Sprague-Dawley) and poor-metabolizer (female dark Agouti) rat strains.
(7) F1 hybrids of white gerbils with red eyes and agouti gerbils with wild coat color had the agouti coat color.
(8) When compared with dark Agouti rats treated with cremophore (n = 10) or not treated at all (n = 12), dark Agouti rats on chronic subcutaneous CsA plus cremophore for 23 days (n = 10) had no difference in kidney histology but had slightly increased liver fatty changes.
(9) The agouti (a) locus acts within the microenvironment of the hair follicle to regulate coat color pigmentation in the mouse.
(10) Tissues from lean agouti and obese yellow mice treated with HP in vitro showed decreased basal and insulin-stimulated glucose oxidation as well as decreased 14C incorporation into lipids.
(11) A breeding test disclosed chimerism of germ cells in two chimeric rats, and there were more pups with agouti coats than with albino coats.
(12) The Itp locus was mapped between the beta-2-microglobulin (B2m) and the agouti (a) loci on chromosome 2.
(13) We find that three different recessive lethal complementation groups are present at the agouti locus, two of which are contained within the al deletion.
(14) Unusual accumulations of Cu in the liver of LEC rats were found, depending on the age of the animals, the metal concentration being more than approximately 20-40 times those of normal LEA rats (Long-Evans rats with an agouti coat color).
(15) alpha-MSH and theophylline had no such effects on hair follicular tyrosinase activity in the non-agouti mice.
(16) Hematologic and serum chemical values established for the agouti were similar to those found in other rodents.
(17) They showed, for example, that the probability of the observed loss of the agouti color in the ATs being by chance is about 0.53 and the probability is nearly 0.50 for there being a spurious line difference, i.e., unrelated to ethanol sensitivity, in which only line had lost the agouti allele.
(18) We have also physically mapped these sequences by in situ hybridization to band H1 of chromosome 2, thus directly confirming previous assignments of the location of the agouti locus.
(19) Infant agoutis showed marginal antibody titers to reovirus type 3 and Toolan's H-1 viruses, and Theiler's GDVII antibodies were detected in juvenile agoutis, but no antibody titers to murine viruses were found in the adult agoutis maintained at our institution.
(20) The recombinants obtained provide valuable resources for determining the direction of chromosome walking experiments designed to clone sequences at the agouti locus.
Hair
Definition:
(n.) The collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.
(n.) One the above-mentioned filaments, consisting, in invertebrate animals, of a long, tubular part which is free and flexible, and a bulbous root imbedded in the skin.
(n.) Hair (human or animal) used for various purposes; as, hair for stuffing cushions.
(n.) A slender outgrowth from the chitinous cuticle of insects, spiders, crustaceans, and other invertebrates. Such hairs are totally unlike those of vertebrates in structure, composition, and mode of growth.
(n.) An outgrowth of the epidermis, consisting of one or of several cells, whether pointed, hooked, knobbed, or stellated. Internal hairs occur in the flower stalk of the yellow frog lily (Nuphar).
(n.) A spring device used in a hair-trigger firearm.
(n.) A haircloth.
(n.) Any very small distance, or degree; a hairbreadth.
Example Sentences:
(1) Cook, who has postbox-red hair and a painful-looking piercing in his lower lip, was now on stage in discussion with four fellow YouTubers, all in their early 20s.
(2) The surface of all cells was covered by a fuzzy coat consisting of fine hairs or bristles.
(3) We have isolated a murine cDNA clone, pCAL-F559, for the calcium-binding protein calcyclin by differential screening of a cDNA library made from RNA isolated from hair follicles of 6-d-old mice.
(4) White hair bulbs which demonstrated no TH activity formed 2SCD, but not 5SCD.
(5) Isolated outer hair cells from the organ of Corti of the guinea pig have been shown to change length in response to a mechanical stimulus in the form of a tone burst at a fixed frequency of 200 Hz (Canlon et al., 1988).
(6) We have reported on a simple and secure method of tying up hair during transplantation surgery for alopecia.
(7) Bone age has been analyzed mixed-longitudinally in a subsample of 370 patients (660 observations) and showed a slight retardation at all ages between 6 and 13 yr. Development of pubic hair of 91 subjects analyzed cross-sectionally was definitely retarded when compared to adequate reference data.
(8) Tumors were induced in athymic, T-cell-deficient nude mice and in syngeneic normal haired mice by treatment with low doses of 3-methylcholantrene (MCA).
(9) As I looked further, I saw that there was blood and hair and what looked like brain tissue intermingled with that to the right area of her skull."
(10) A new method of staining the keratin filament matrix allowing a visualization of the filaments in cross section of hair fibres has been developed.
(11) However, in subjects with alopecia there was no such difference and the growth rate of all the hairs showed a continuous distribution.
(12) No infection threads were found to penetrate either root hairs or the nodule cells.
(13) After 7 days, various stages of sensory hair degeneration could be observed.
(14) This review of androgenetic alopecia (AA) in women provides a summary of hair physiology and biochemistry, a general discussion of AA, and a brief description of other types of hair loss in women.
(15) Subungual hair penetration appears to be much less common.
(16) Steep longitudinal and transverse gradients of glycogen are known to exist in the organ of Corti of the guinea pig, with preferential accumulation in the outer hair cells of the apical turns.
(17) Of four normal tissues assessed, two (hair follicles and tissues responsible for development of leg contractures) showed no change in radioresponse after treatment with indomethacin, one (hematopoietic tissue) exhibited radioprotection, and one (jejunum) exhibited slight radiosensitization (enhancement factor, 1.12).
(18) On the other hand, the total number of missing hair cells, irrespective of location, was a good, general indicator of the hearing capacity in a given ear.
(19) The objective was to determine whether the parent axonal impulse train elicited by dual-hair stimulation was due to a temporal combining ("mixing"; Fukami, 1980) of the impulse trains elicited in the parent axons by the same stimulation to each hair alone.
(20) In addition to descriptions of variants of the root appearance for hairs removed from follicles in the three classical growth phases, several other commonly occurring root configurations are described and illustrated with photomicrographs.