(n.) A rodent of the genus Dasyprocta, about the size of a rabbit, peculiar to South America and the West Indies. The most common species is the Dasyprocta agouti.
Example Sentences:
(1) Total cellular proteins from the livers of 4-, 16- and 52-week-old hepatitis- and hepatoma-predisposed Long-Evans Cinnamon (LEC) rats were compared to those from the livers of the corresponding control rats [Long-Evans Agouti (LEA) rats] by two-dimensional gel electrophoresis.
(2) Nonagouti rats were significantly easier to approach, capture, and handle than their agouti sibs.
(3) We have characterized a gene encoding a novel 131 amino acid protein that we propose is the one gene associated with the agouti locus.
(4) The cortical representation of the contralateral visual field in area 17 of the agouti's brain was studied by multiunit recording.
(5) Future experiments will determine the type of protein(s) encoded by the agouti coat color locus and establish the mechanism by which these protein(s) control the nature and timing of pigment production by melanocytes in the hair follicle.
(6) In a preliminary study, different rates of N-, O- and N,O- demethylation of dextromethorphan to yield D-methoxymorphinane, dextrorphan and D-hydroxymorphinane, respectively, were found in extensive- (Sprague-Dawley) and poor-metabolizer (female dark Agouti) rat strains.
(7) F1 hybrids of white gerbils with red eyes and agouti gerbils with wild coat color had the agouti coat color.
(8) When compared with dark Agouti rats treated with cremophore (n = 10) or not treated at all (n = 12), dark Agouti rats on chronic subcutaneous CsA plus cremophore for 23 days (n = 10) had no difference in kidney histology but had slightly increased liver fatty changes.
(9) The agouti (a) locus acts within the microenvironment of the hair follicle to regulate coat color pigmentation in the mouse.
(10) Tissues from lean agouti and obese yellow mice treated with HP in vitro showed decreased basal and insulin-stimulated glucose oxidation as well as decreased 14C incorporation into lipids.
(11) A breeding test disclosed chimerism of germ cells in two chimeric rats, and there were more pups with agouti coats than with albino coats.
(12) The Itp locus was mapped between the beta-2-microglobulin (B2m) and the agouti (a) loci on chromosome 2.
(13) We find that three different recessive lethal complementation groups are present at the agouti locus, two of which are contained within the al deletion.
(14) Unusual accumulations of Cu in the liver of LEC rats were found, depending on the age of the animals, the metal concentration being more than approximately 20-40 times those of normal LEA rats (Long-Evans rats with an agouti coat color).
(15) alpha-MSH and theophylline had no such effects on hair follicular tyrosinase activity in the non-agouti mice.
(16) Hematologic and serum chemical values established for the agouti were similar to those found in other rodents.
(17) They showed, for example, that the probability of the observed loss of the agouti color in the ATs being by chance is about 0.53 and the probability is nearly 0.50 for there being a spurious line difference, i.e., unrelated to ethanol sensitivity, in which only line had lost the agouti allele.
(18) We have also physically mapped these sequences by in situ hybridization to band H1 of chromosome 2, thus directly confirming previous assignments of the location of the agouti locus.
(19) Infant agoutis showed marginal antibody titers to reovirus type 3 and Toolan's H-1 viruses, and Theiler's GDVII antibodies were detected in juvenile agoutis, but no antibody titers to murine viruses were found in the adult agoutis maintained at our institution.
(20) The recombinants obtained provide valuable resources for determining the direction of chromosome walking experiments designed to clone sequences at the agouti locus.
Gouty
Definition:
(a.) Diseased with, or subject to, the gout; as, a gouty person; a gouty joint.
(a.) Pertaining to the gout.
(a.) Swollen, as if from gout.
(a.) Boggy; as, gouty land.
Example Sentences:
(1) Low density lipoprotein (LDL) is the major plasma inhibitor of neutrophil oxidative and lytic responses to monosodium urate crystals and may function to modulate acute gouty inflammation.
(2) Thus, acute gouty arthritis is now recognized as an example of "crystal induced" synovitis.
(3) By the mid 20th century, however, the apparent decline of the gout in Europe and North America and the breakup of the gouty diathesis in those lands had been more than compensated by their large-scale reappearance in the Maori and in other indigenous inhabitants of the Pacific Basin who, at first sight, appeared to have become one large gouty family.
(4) Fifteen cases of acute gouty bursitis were seen among 136 crystal-proved cases of gout.
(5) Tenoxicam administered orally, rectally or parenterally is an effective analgesic and anti-inflammatory agent for the symptomatic treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and various rheumatic conditions such as tendinitis, bursitis, sciatica, back pain and gouty arthritis.
(6) The authors emphasize that the possibility of a septic arthritis should always be considered in the gouty patient, and not only in the elderly, as stressed in the literature, but also in younger patients.
(7) Many patients have gouty symptoms, especially after treatment with Busulfan, and many have an unexplained hemorrhagic tendency, making major operations a risk.
(8) Synovial fluids from 75 patients were analyzed, comprising the following disease groups: i) rheumatoid arthritis (n = 42), ii) osteoarthritis (n = 20), iii) gouty arthritis (n = 5), and iv) reactive arthritis (Reiter's disease, n = 8).
(9) One patient did not take any medical treatment and died suddenly when he was 19 years old, but showed no gouty signs.
(10) This latter observation raises doubts about the postulated physiological role of LDL in terminating the acute gouty attack.
(11) A double-blind study was carried out to compare the effects of ketoprofen and phenylbutazone in acute gouty arthritis.
(12) This suggests that the amount of LDL coating intraarticular urate crystals could vary during the course of a gouty paroxysm.
(13) In the case of two gouty groups divided according to the existence of gouty heredity, tophi or renal impairment, adenosine deaminase and inosine phosphorylase activity in the two groups were not significantly different.
(14) The data suggest an increase in the rate of purine turnover in aging gouty fibroblasts compared with normal fibroblasts.
(15) The case emphasized that patients with this deficiency may escape diagnosis during childhood and that internists should consider the diagnosis in adolescents or young adults with acute gouty arthritis or tophaceous gout.
(16) A rare case of gouty tophus localized to the temporomandibular joint is reported on by which alimentary troubles were caused.
(17) Monosodium urate (MSU)-induced synovitis in the dog's stifle (knee joint) is similar to an acute gouty attack in man in which a loss of function of the joint correlates with massive influx of neutrophils and the release of an assortment of inflammatory mediators (e.g.
(18) These findings suggest that the association of membranous nephropathy should be considered in patients with gout having moderate to severe proteinuria and that RTE may be involved in the pathogenesis of subepithelial deposits in gouty membranous nephropathy.
(19) (3) Synovial fluid from one gouty patient accelerated urate nucleation, while that from one rheumatoid patient inhibited nucleation.
(20) Striking elevations were also present in 2 patients who had acute gouty arthritis.