What's the difference between agrin and embryonic?
Agrin
Definition:
(adv. & a.) In the act of grinning.
Example Sentences:
(1) These results provide the first demonstration that embryonic neurons supply agrin-like molecules to the synapses they form with embryonic muscle cells.
(2) The stimulation of the expression of agrin-related molecules in these long-term cultures requires the presence of chick embryo extract or fetal calf serum.
(3) Agrin, a protein isolated from the synapse-rich electric organ of Torpedo californica, induces the formation of specializations on myotubes in culture which resemble the post-synaptic apparatus at the vertebrate skeletal neuromuscular junction.
(4) Agrin enriched by immunoaffinity chromatography from the central nervous system induced large numbers of AChR aggregates on cultured myotubes.
(5) We conclude that agrin released by rat motor neurons induced the chick myotubes to aggregate AChRs.
(6) Agrin-induced formation of AChR aggregates was not prevented by inhibition of protein synthesis, consistent with our previous results that agrin-induced accumulation of AChRs occurs by lateral migration.
(7) The rat agrin protein is concentrated at synapses, where it may play a role in development and regeneration.
(8) Immunofluorescence shows that on myotubes incubated with agrin at 4 degrees C, agrin binds in a uniform, finely punctate pattern that correlates poorly with the distribution of AChRs.
(9) By contrast, actin (visualized with fluorescein-phalloidin) and tropomyosin did not show specific associations with agrin-induced AChR clusters.
(10) In the present study we examined the role of extracellular matrix components in agrin-induced differentiation.
(11) Myotubes stimulated with agrin at 37 degrees C for greater than or equal to 2 hr show a coclustering of agrin binding sites and AChRs.
(12) The accumulation of AChE and BuChE into agrin-induced aggregates occurred in the absence of any change in the amount, rate of synthesis, accumulation, and release, or molecular forms of either enzyme.
(13) We also characterized the expression of muscle-derived agrin-like molecules at clusters of AChR.
(14) Here I report that the major agrin-like proteins from the nervous system and other tissues of the chicken are immunochemically and biochemically similar.
(15) Thus, in developing muscle, agrin or a closely related molecule (a) is expressed before AchR clusters are detected; (b) is colocalized with the earliest AchR clusters formed; and (c) can be expressed in muscle and at sites of high AchR density independently of innervation.
(16) These results demonstrate that expression of a single gene encoding agrin confers receptor clustering that is restricted to specific sites of cell-muscle contact.
(17) Other lines of study have provided clues as to how nerve-derived (extracellular) AChR-cluster inducing factors such as agrin might activate 43k-driven postsynaptic membrane specialization.
(18) However, as dorsal and ventral premuscle masses condensed (stage 22-23), mesenchymal immunoreactivity for laminin and agrin-like proteins, but not the proteoglycan, became concentrated in these myogenic regions.
(19) Immunofluorescent staining with an anti-agrin antibody reactive at Rana but not at Xenopus neuromuscular junctions was positive only at cross-species nerve-muscle contacts involving Rana neurons.
(20) Here we present evidence that agrin is highly concentrated in the cell bodies of motor neurons and is transported to axon terminals which is consistent with the agrin hypothesis.
Embryonic
Definition:
(a.) Of or pertaining to an embryo; embryonal; rudimentary.
Example Sentences:
(1) Brain and ganglia of embryonic Periplaneta americana were grown for 2 to 3 weeks in a chemically defined medium.
(2) It was found that the skeletal muscle enzyme of the chick embryo is independent of the presence of creatine and consequently is another constitutive enzyme like the creatine kinase of the early embryonic chick heart.
(3) Right orchiectomy and retroperitoneal lymph node dissection for embryonal carcinoma had been performed 5 years earlier.
(4) Blocks of hippocampal tissue containing the fascia dentata were taken from late embryonic and newborn rats and transplanted to the hippocampal region of other newborn and young adult rats.
(5) In conclusion, autoimmune thyroiditis in an animal model can be prevented by reducing thyroidal iodine or its metabolism and optimal effects require intervention at the embryonic stage.
(6) On embryonic day 3.5 (E3.5), 1 day after surgery, there is a 42% average increase in volume of the polyganglia compared with the corresponding DRG on the unoperated side.
(7) Isoenzyme LDH4 was absent in the human pancreas in all the studied periods of embryonic development.
(8) The mRNA data of the developing gut correspond with previous protein data, which showed that the shorter Mr 210,000 polypeptide predominates during earlier developmental stages and the larger Mr 260,000 polypeptide appears later in the embryonic gut (Aufderheide, E., and P. Ekblom.
(9) Almost nothing is known about nature and timing of the embryonic cues which induce or initiate spicule formation by these cells.
(10) Implantation is dependent on embryonic age and is independent of endometrial maturation within this window.
(11) The junctional currents were already constant 1 ms after step changes in the junctional voltage; this was three orders of magnitude faster than the other known examples of voltage-controlled gap junctions between embryonic cells.
(12) Zona pellucida solubility, plasminogen activator production, and plasminogen conversion to plasmin increased as embryonic stage advanced; however, plasminogen activator production and plasmin conversion to plasmin were poorly correlated with zona pellucida solubility.
(13) He fashioned alliances with France in the 1950s, and planted the seeds for Israel’s embryonic electronics and aircraft industries.
(14) Both kinds of experiments show that 1, 25-(OH)2D3 has effects on embryonic bone which are typical for high concentrations of parathyroid hormone (PTH).
(15) p50B is able to form heteromeric kappa B-binding complexes with RelB, as well as with p65 and p50, the two subunits of NF-kappa B. Transient-transfection experiments in embryonal carcinoma cells demonstrate a functional cooperation between p50B and RelB or p65 in transactivation of a reporter plasmid dependent on a kappa B site.
(16) At the adult neuromuscular junction, acetylcholine (ACh) receptors are highly localized at the subsynaptic membrane, whereas, embryonic myotubes before innervation have receptors distributed over the entire surface.
(17) Embryonal carcinomas were found in 15 tumours, two being of pure type and the remaining 13 a part of mixed tumours.
(18) A large portion of the N-terminal globule of human collagen VI was prepared from the culture medium of stably transfected human embryonic kidney cell clones.
(19) The tissues were derived from the three germ layers and were prevalently mature; only a bit of them was represented by embryonic mesenchymal tissue.
(20) Phosphotyrosine-modified proteins were also abundant in and highly restricted to the process-rich layers of the embryonic optic tectum.