What's the difference between agrin and satisfaction?

Agrin


Definition:

  • (adv. & a.) In the act of grinning.

Example Sentences:

  • (1) These results provide the first demonstration that embryonic neurons supply agrin-like molecules to the synapses they form with embryonic muscle cells.
  • (2) The stimulation of the expression of agrin-related molecules in these long-term cultures requires the presence of chick embryo extract or fetal calf serum.
  • (3) Agrin, a protein isolated from the synapse-rich electric organ of Torpedo californica, induces the formation of specializations on myotubes in culture which resemble the post-synaptic apparatus at the vertebrate skeletal neuromuscular junction.
  • (4) Agrin enriched by immunoaffinity chromatography from the central nervous system induced large numbers of AChR aggregates on cultured myotubes.
  • (5) We conclude that agrin released by rat motor neurons induced the chick myotubes to aggregate AChRs.
  • (6) Agrin-induced formation of AChR aggregates was not prevented by inhibition of protein synthesis, consistent with our previous results that agrin-induced accumulation of AChRs occurs by lateral migration.
  • (7) The rat agrin protein is concentrated at synapses, where it may play a role in development and regeneration.
  • (8) Immunofluorescence shows that on myotubes incubated with agrin at 4 degrees C, agrin binds in a uniform, finely punctate pattern that correlates poorly with the distribution of AChRs.
  • (9) By contrast, actin (visualized with fluorescein-phalloidin) and tropomyosin did not show specific associations with agrin-induced AChR clusters.
  • (10) In the present study we examined the role of extracellular matrix components in agrin-induced differentiation.
  • (11) Myotubes stimulated with agrin at 37 degrees C for greater than or equal to 2 hr show a coclustering of agrin binding sites and AChRs.
  • (12) The accumulation of AChE and BuChE into agrin-induced aggregates occurred in the absence of any change in the amount, rate of synthesis, accumulation, and release, or molecular forms of either enzyme.
  • (13) We also characterized the expression of muscle-derived agrin-like molecules at clusters of AChR.
  • (14) Here I report that the major agrin-like proteins from the nervous system and other tissues of the chicken are immunochemically and biochemically similar.
  • (15) Thus, in developing muscle, agrin or a closely related molecule (a) is expressed before AchR clusters are detected; (b) is colocalized with the earliest AchR clusters formed; and (c) can be expressed in muscle and at sites of high AchR density independently of innervation.
  • (16) These results demonstrate that expression of a single gene encoding agrin confers receptor clustering that is restricted to specific sites of cell-muscle contact.
  • (17) Other lines of study have provided clues as to how nerve-derived (extracellular) AChR-cluster inducing factors such as agrin might activate 43k-driven postsynaptic membrane specialization.
  • (18) However, as dorsal and ventral premuscle masses condensed (stage 22-23), mesenchymal immunoreactivity for laminin and agrin-like proteins, but not the proteoglycan, became concentrated in these myogenic regions.
  • (19) Immunofluorescent staining with an anti-agrin antibody reactive at Rana but not at Xenopus neuromuscular junctions was positive only at cross-species nerve-muscle contacts involving Rana neurons.
  • (20) Here we present evidence that agrin is highly concentrated in the cell bodies of motor neurons and is transported to axon terminals which is consistent with the agrin hypothesis.

Satisfaction


Definition:

  • (n.) The act of satisfying, or the state of being satisfied; gratification of desire; contentment in possession and enjoyment; repose of mind resulting from compliance with its desires or demands.
  • (n.) Settlement of a claim, due, or demand; payment; indemnification; adequate compensation.
  • (n.) That which satisfies or gratifies; atonement.

Example Sentences:

  • (1) Results indicate that energy had not returned to patients' satisfaction in 37% of the cases.
  • (2) For enrolled nurses an increase in "Intrinsic Job Satisfaction" was less well maintained and no differences were found over time on "Patient Focus".
  • (3) Although there was already satisfaction in the development of dementia-friendly pharmacies and Pride in Practice, a new standard of excellence in healthcare for gay, lesbian and bisexual patients, the biggest achievement so far was the bringing together of a strategic partnership of 37 NHS, local government and social organisations.
  • (4) A subgroup of 40 patients was asked to complete a brief survey on medical care information and satisfaction.
  • (5) Regression analysis revealed a highly positive relationship between work performed and overall job satisfaction for both groups, although the work variable contributed more to multiskilled practitioners' overall satisfaction.
  • (6) Autonomy, sense of accomplishment and time spent in patient care ranked as the top three factors contributing to job satisfaction.
  • (7) Martin O’Neill spoke of his satisfaction at the Republic of Ireland’s score draw in the first leg of their Euro 2016 play-off against Bosnia-Herzegovina – and of his relief that the match was not abandoned despite the dense fog that descended in the second half and threatened to turn the game into a farce.
  • (8) The content and design of the treatment obviously had a positive influence on patient satisfaction.
  • (9) Access to general practitioners was found to be the most important determinant of global satisfaction.
  • (10) Seventy-two per cent of the 226 respondents had used the service, 23% more than four times, and 94% indicated satisfaction at having such a service available, with only 1% expressing dissatisfaction.
  • (11) Transfer of nonprofessional tasks out of nursing and reduction of tension arising from reduced responsibility of nurses for coordinating activities with ancillary departments are possible explanations for the positive relation between the presence of SUM and professional nurses' satisfaction.
  • (12) Psychological risk factors predicted donor candidates' decisions to participate and their compliance but were not predictive (within the group that completed a cycle) of donor satisfaction as follow-up or recipient pregnancy.
  • (13) A total of 54 family caregivers of elderly dementia patients completed interviews and questionnaires assessing the severity of patient impairment and caregiving stressors; caregiver appraisals, coping responses, and social support and activity; and caregiver outcomes, including depression, life satisfaction, and self-rated health.
  • (14) The analysis of four surveys on elder people shows that health, income, social integration, knowledge about aging, plans for retirement, good ecological conditions, life satisfaction, and a low age seem to be general resources.
  • (15) Although there continue to be methodologic problems in outcome evaluation research of multidisciplinary treatment of sexual dysfunction, follow-up studies generally indicate improvements in sexual functioning, satisfaction, and self-esteem.
  • (16) Encouragement is a powerful nursing strategy, increasing both nursing effectiveness and feelings of job satisfaction.
  • (17) At the interview those with conventional ileostomies expressed better preoperative comprehension of the procedure and more satisfaction about its life-saving nature; nevertheless, they experienced more negative emotional reactions, such as bitterness, after the operation.
  • (18) 's Life Satisfaction Index A (LSIA) is a widely used instrument for measuring subjective well-being among elderly adults, and the generalizability of its structure in different cultural contexts should be established [1].
  • (19) Over the years he has been through 20 Ofsted inspections, with all the anxiety – and sometimes satisfaction – that entails.
  • (20) The leadership of 212 chapters of an organization called Mothers Against Drunk Driving was surveyed to obtain data on chapter emphasis, satisfaction, future involvement and perception of most effective countermeasures.

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