(interj.) An exclamation expressing, by different intonations, triumph, mixed with derision or irony, or simple surprise.
(n.) A sunk fence. See Ha-ha.
Example Sentences:
(1) The coding sequence for Spirulina platensis acetohydroxy acid synthase (AHAS, EC 4.1.3.18) is shown to be contained within a 4.2 Kb ClaI fragment (ilvX) that has been cloned from a recombinant lambda library.
(2) The acetohydroxy acid synthase (AHAS) isozymes from enterobacteria are each composed of a large and small subunit in an alpha 2 beta 2 structure.
(3) The potency of L-valine as an inhibitor of Zea mays acetohydroxyacid synthase (AHAS) is increased more than 8000-fold on conversion to its N-phthalyl anilide derivative which is active at 2 microM.
(4) Evidence is presented that suggests the presence of multiple genetic regions for synthesis and control of the valine-sensitive AHAS activity.
(5) The mutant strain, growing in minimal medium, exhibits a partial growth limiatation and derepression of AHAS, owing to deficient synthesis of isoleucine.
(6) Autoimmune hemolytic anemia (AHA) is uncommon in childhood.
(7) The subjects who were older and had higher levels of plasma LDL cholesterol and total fat intake at baseline experienced better plasma LDL cholesterol response to the AHA diet.
(8) AHA axons staying ventral projected to the supramammillary region, ventral tegmental area, raphe nuclei and midbrain reticular formation.
(9) The glutamic acid (Glu) concentration was significantly higher in AHa (p less than 0.02), CAH (p less than 0.001) and CPH (p less than 0.001) and the tyrosine (Tyr) concentration was significantly higher in AHa (p less than 0.02), CPH (p less than 0.001), CAH (p less than 0.001) and LC (p less than 0.001) than they were in the controls.
(10) The surgical group showed a significantly higher humoral immune response than the AMI group when analyzed for AHA and anti-contractile protein antibodies.
(11) Whereas medial PO-AHA lesions were associated with normal body length and weight and evidence of estrogen secretion, anterior hypothalamic cuts produced increased linear growth and body weight and signs of functional castration.
(12) SPECT images were compared with left ventriculography (LVG); vertical long-axial ECT images with segments 1-5 of LVG by the AHA classification, and horizontal ECT long-axial images with segments 6 and 7 of LVG, respectively.
(13) "A ban on sales of alcohol below the cost of duty plus VAT will affect less than 1% of products sold in shops and off-licences," said Dr Vivienne Nathanson, director of professional activities for the British Medical Association, an AHA member.
(14) Inhibition of the enzyme and of root growth by the valine derivatives may result from binding at or near the site involved in feedback control of AHAS by L-valine.
(15) Discrete lesions in the anterior hypothalamus (AHA) of the guinea pig brain reduce the anaphylactic contraction of the trachea in vitro after active in vivo sensitization by 40%.
(16) And then I thought, aha, when it comes to shooting my close-ups, I won't move, so he won't be able to cut it in.
(17) Medial but not lateral PO-AHA lesions caused elevated nonstress plasma GH levels at 2, 14, 17, and 23 weeks after surgery, but normal levels were obtained at autopsy at 27 weeks.
(18) Evaluation of urinary excretion data suggests that patients with compromised renal function have low recoveries of AHA in the urine.
(19) In cultures where both IgM AHA and total IgM secretion were measured, a much greater T cell dependence for AHA production was apparent.
(20) AHA positivity was unrelated to the type of joint involvement, disease activity, and drug regimen.
Ara
Definition:
(n.) The Altar; a southern constellation, south of the tail of the Scorpion.
(n.) A name of the great blue and yellow macaw (Ara ararauna), native of South America.
Example Sentences:
(1) The antitumor effect of C18PCA and Ara-C was investigated against the P388 ascites tumor in BDF1 mice.
(2) However, the walker 256 intramuscular tumor did not respond to ARA-C capsules implanted, and the animals died at the same rate as the controls, with large ulcerated tumor masses and some metastasis.
(3) 5 heavily pretreated patients with chronic lymphocytic leukaemia or non-Hodgkin lymphoma resistant to alkylating agents were treated with low-dose cytosine arabinoside (ARA-C).
(4) Rat liver microsomes demethylated ara-DMAP much more rapidly than human liver microsomes did.
(5) Enhanced ara-CTP formation was observed in cells lacking cytidine deaminase (L1 210 and HL60), indicating that 3-deazauridine inhibition of deoxycytidylate deaminase may be important in this drug interaction.
(6) This study demonstrates the mutagenic properties of F-ara-A and ara-A and provides evidence for mechanisms by which the arabinosyl nucleosides induce mutation.
(7) Patient cells had low rates for ara-C transport as compared with human and murine experimental cells and correspondingly low binding capacities for the nucleoside transport inhibitor, nitrobenzylmercaptopurine riboside (NBMPR).
(8) The inhibitions by ara-GTP and 9-beta-D-arabinofuranosyladenine 5'-triphosphate were due to competition or partial competition 5'-triphosphate were due to competition or partial competition with deoxynucleoside triphosphate with the same base.
(9) The incorporation of F-ara-A monophosphate into mRNA resulted in premature termination of the RNA transcript and impaired its functioning as a template for protein synthesis.
(10) Pharmacological studies of 5'-esters of 1 beta-D-arabinofuranosylcytosine (ara-C) were performed in three species (mouse, pig, and man).
(11) These results provide some support for the view that cell kill may not be the only basis for the chemotherapeutic effectiveness of ara-C.
(12) Accelerating test at a constant temperature indicates that liposome-entrapped Ara-A has certain chemical stability.
(13) Although statistically significant, the effect of DP on ara-CTP retention in AML blasts was much less pronounced than that previously observed in L5178Y leukemia.
(14) He was treated with the combination chemotherapy of BACOD with high dose ara-C or methotrexate followed by 4 doses of autologous LAK cell infusion resulting in no significant response.
(15) Regardless whether cyclo-C or ara-C is injected, the plasma decay curve of the resultant ara-C is biphasic, with calculated half-lives of 40 min and 2-2.5 hr.
(16) Serial measurements of DNA synthesis and net intracellular ara-C metabolism demonstrated marked increases in both determinants in day 8 residual tumor when compared with the pretreatment cells for newly diagnosed adults achieving complete remission but not for TST-refractory patients.
(17) Determination of the intracellular content of the active metabolite of ara-C, ara-CTP, excluded more prolonged retention of the drug as the basis for potentiation of cytotoxicity.
(18) With the aim of improving the treatment of AML patients the activities of selected nucleoside metabolizing enzymes of possible implication for the initial metabolism of Ara-C have been studied in leukemic and normal cells.
(19) Ara-C. We conclude that prophylactic CNS therapy may cause cognitive dysfunctions.
(20) This was possible because the Ara test, for volatile compounds (such as vinyl bromide), did not require the use of special vaporization techniques, which are difficult to evaluate quantitatively for mutagenic activity.