(interj.) An exclamation expressive of sorrow, pity, or apprehension of evil; -- in old writers, sometimes followed by day or white; alas the day, like alack a day, or alas the white.
Example Sentences:
(1) No difference in therapeutic activity between CNC-ala-17-E2 and CNC-ala could be observed in a transplanted rat leukemia (L 5222).
(2) In each subject, the activity in leucocytes of delta-aminolaevulinic acid (ALA) synthase increased and that of protoporphyrinogen (proto) oxidase decreased during the first week of therapy.
(3) The IL-8 isolated from each of these cell types is a mixture of two IL-8 polypeptides, one consisting of 72 amino acids (herein called [ser-IL-8]72) and the other 77 amino acids (an N-terminal extended form herein called [ala-IL-8]77).
(4) Two EGZ-derived proteins were engineered in which either His98 or Glu133 amino acid was converted to an Ala residue.
(5) In cirrhosis there was a decrease, of zinc (-40%) albumin (-38%) and of activity of ALA D (-48%) and an increase in blood lead (+80%).
(6) We have named them bombolitin I (Ile-Lys-Ile-Thr-Thr-Met-Leu-Ala-Lys-Leu-Gly-Lys-Val-Leu-Ala-His-Val-NH2 ), bombolitin II (Ser-Lys-Ile-Thr-Asp-Ile-Leu-Ala-Lys-Leu-Gly-Lys-Val-Leu-Ala-His-Val-NH2 ), bombolitin III (Ile-Lys-Ile-Met-Asp-Ile-Leu-Ala-Lys-Leu-Gly-Lys-Val-Leu-Ala-His-Val-NH2 ), bombolitin IV (Ile-Asn-Ile-Lys-Asp-Ile-Leu-Ala-Lys-Leu-Val-Lys-Val-Leu-Gly-His-Val-NH2 ), and bombolitin V (Ile-Asn-Val-Leu-Gly-Ile-Leu-Gly-Leu-Leu-Gly-Lys-Ala-Leu-Ser-His-Leu-NH2 ).
(7) To confirm this, ALA-S activity was then directly measured in intact reticulocytes, and it was shown that ethanol indeed inhibited its activity.
(8) All inhibitors had no effect on L-Ala uptake into brush-border membrane vesicles in presence of Na+ gradient.
(9) Specimens from the bone marrow taken were by trephine biopsy from the sternum, ala ossis ilii and spine.
(10) Paraproteins, usually of the IgG-kappa isotype, were found in the sera of a significant number of HIV-1-infected individuals as were antibodies to lymphocytes (ALAs).
(11) With the use of the method Chick Embryotoxicity Screening Test II (CHEST II), the potential neuropeptides L-prolyl-L-leucyl-glycinamide (MIF), cyclo(1-aminocyclo-pentanecarbonyl-L-alanyl)[cyclo(Acp-Ala)] and cyclo(glycyl-L-leucyl)[Cyclo(Gly-Leu)] were tested in the critical developmental periods of d 1.5 to 4 of chick embryogenesis in order to objectively examine their undesirable interactions with the developing morphogenetic systems of the brain, eye, face, body wall, limbs, trunk and heart.
(12) The differential scanning calorimetry (DSC) studies demonstrate an increased susceptibility of the Ala 183----Pro mutant to thermal denaturation.
(13) Mutants of Escherichia coli which require 5-aminolaevulinic acid (5-ALA), the first intermediate of haem biosynthesis, do not respond to haemin and porphyrins.
(14) The lipid-mobilizing activity of a synthetic peptide, NH2-Phe-Glu-Glu-Ala-Tyr-Ile-Pro-Lys-Glu-Gln-Lys-Tyr-Ser-Phe-COOH, corresponding to the 31-44 amino-acid sequence of human growth hormone, was studied.
(15) The replacements for Glu-43 (Asp, Gln, Asn, Ser, and Ala) both decreased the catalytic efficiency and changed the one- and two-dimensional NMR spectral properties of the mutant enzymes.
(16) Alas, for Jones, they found more of his ill-gotten gains in another plot he had perhaps forgotten to mention.
(17) The structures of two crystal forms of Boc-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-OMe have been determined.
(18) Daily intra-VTA injections of the mu opioid agonist Tyr-D-Ala-Gly-NMe-Phe-Gly-ol enhanced the behavioral stimulant effect of acute morphine.
(19) The (beta-chloro-, (beta, beta-dichloro-, and (beta, beta, beta-trichloro-alpha-aminoethyl)phosphonic acids have been synthesized and their inhibitory properties on the alanine racemases [EC 5.1.1.1] and the D-Ala:D-Ala ligases [EC 6.3.2.4] from Pseudomonas aeruginosa and Streptococcus faecalis have been evaluated.
(20) Angiotensin converting enzyme activity was measured in intact aortic rings utilizing the synthetic tripeptide [3H]-benzoyl-Phe-Ala-Pro as the substrate.
Las
Definition:
(n.) A lace. See Lace.
(a. & adv.) Less.
Example Sentences:
(1) Originally, it was to be named Le Reve, after one of the Picassos that Wynn and his wife own; but, as of last month, it is to be called Wynn Las Vegas, embodying a dream of a different kind.
(2) "We expect LSCBs [local safeguarding children boards], LAs [local authorities] police forces and other agencies to do all they can to identify victims and abusers and we are looking at how we can improve data-sharing."
(3) Racing was heavily hit, with meetings at Ffos Las, Sandown and Wetherby cancelled.
(4) To assess the value of laparoscopic appendectomy (LA) in childhood, we prospectively compared 14 LAs with 50 open appendectomies (OA) over 6 months in a single children's hospital.
(5) The results obtained provided direct evidence for the notion that: LAs interact preferentially with inactivated Na+ channels and stabilize their inactivated conformation ("drug-induced slow inactivation": SI); and SI underlies the cumulative inhibition of INa during repetitive membrane stimulation.
(6) Moderate maternal toxicity was observed among mice treated with LAS, 0.3% and mild maternal toxicity in rats receiving LAS 3% or soap 30% and rabbits receiving LAS 0.3%.
(7) When Contostavlos wanted to stay an extra night at the luxury Las Vegas hotel, he told the court, his editors vetoed it.
(8) The deal gave Penn a Las Vegas casino for a fraction of what it cost to build the 390-room resort.
(9) With time and sufficient promotion by pH fluctuations or metal-complexing agents, DIP and LAS expand.
(10) Apple has used the month of January to launch revolutionary products before, in part as a way of diverting attention from its rivals presenting their latest inventions at the Consumer Electronics Show in Las Vegas, which Apple does not attend, and that takes place the same month.
(11) Moments later, Deputy Chief Tom Roberts, of Las Vegas Metro, defused the situation by delivering the announcement that Cliven Bundy's cattle would be returned within 30 minutes.
(12) The lymph nodes of patients with LAS were mostly stage I with marked follicular hyperplasia.
(13) Forty were lactose malabsorbers (LMs) and 31 were absorbers (LAs), according to a standard oral lactose tolerance test.
(14) Thirteen patients affected with unexplained lymphoadenopathy, fever, weight loss, and diarrhea (lymphoadenopathy syndrome; LAS) were evaluated for the possible appearance of acquired immunodeficiency syndrome (AIDS) and for immunological and virological characterization.
(15) Detectable levels of both cytokines were found in 34% of ASY and LAS patients and only rarely were detectable in ARC and AIDS patients.
(16) The possibility to correlate the latter findings with a better knowledge of LAS evolution and prognosis is discussed.
(17) The purpose of the present study was to propose an alternative measurement process which addresses some of the existing problems by estimating the lost attachment surface area (LAS) and the remaining attachment surface area (RAS) from a combination of clinical measurements.
(18) Antibody titres against the viral proteins also seemed to be highest in cases with LAS.
(19) Receptor autophosphorylation determined using Triton X-100 extracts of the fibroblasts was decreased in LA1 and LA3, but normal in LA2 and LAS.
(20) Facebook Twitter Pinterest ‘The past in all its mortal beauty’: Las Meninas, the 1656 Velazquez masterpiece that held Laura Cumming spellbound at the Prado in Madrid.