(interj.) An exclamation expressive of sorrow, pity, or apprehension of evil; -- in old writers, sometimes followed by day or white; alas the day, like alack a day, or alas the white.
Example Sentences:
(1) No difference in therapeutic activity between CNC-ala-17-E2 and CNC-ala could be observed in a transplanted rat leukemia (L 5222).
(2) In each subject, the activity in leucocytes of delta-aminolaevulinic acid (ALA) synthase increased and that of protoporphyrinogen (proto) oxidase decreased during the first week of therapy.
(3) The IL-8 isolated from each of these cell types is a mixture of two IL-8 polypeptides, one consisting of 72 amino acids (herein called [ser-IL-8]72) and the other 77 amino acids (an N-terminal extended form herein called [ala-IL-8]77).
(4) Two EGZ-derived proteins were engineered in which either His98 or Glu133 amino acid was converted to an Ala residue.
(5) In cirrhosis there was a decrease, of zinc (-40%) albumin (-38%) and of activity of ALA D (-48%) and an increase in blood lead (+80%).
(6) We have named them bombolitin I (Ile-Lys-Ile-Thr-Thr-Met-Leu-Ala-Lys-Leu-Gly-Lys-Val-Leu-Ala-His-Val-NH2 ), bombolitin II (Ser-Lys-Ile-Thr-Asp-Ile-Leu-Ala-Lys-Leu-Gly-Lys-Val-Leu-Ala-His-Val-NH2 ), bombolitin III (Ile-Lys-Ile-Met-Asp-Ile-Leu-Ala-Lys-Leu-Gly-Lys-Val-Leu-Ala-His-Val-NH2 ), bombolitin IV (Ile-Asn-Ile-Lys-Asp-Ile-Leu-Ala-Lys-Leu-Val-Lys-Val-Leu-Gly-His-Val-NH2 ), and bombolitin V (Ile-Asn-Val-Leu-Gly-Ile-Leu-Gly-Leu-Leu-Gly-Lys-Ala-Leu-Ser-His-Leu-NH2 ).
(7) To confirm this, ALA-S activity was then directly measured in intact reticulocytes, and it was shown that ethanol indeed inhibited its activity.
(8) All inhibitors had no effect on L-Ala uptake into brush-border membrane vesicles in presence of Na+ gradient.
(9) Specimens from the bone marrow taken were by trephine biopsy from the sternum, ala ossis ilii and spine.
(10) Paraproteins, usually of the IgG-kappa isotype, were found in the sera of a significant number of HIV-1-infected individuals as were antibodies to lymphocytes (ALAs).
(11) With the use of the method Chick Embryotoxicity Screening Test II (CHEST II), the potential neuropeptides L-prolyl-L-leucyl-glycinamide (MIF), cyclo(1-aminocyclo-pentanecarbonyl-L-alanyl)[cyclo(Acp-Ala)] and cyclo(glycyl-L-leucyl)[Cyclo(Gly-Leu)] were tested in the critical developmental periods of d 1.5 to 4 of chick embryogenesis in order to objectively examine their undesirable interactions with the developing morphogenetic systems of the brain, eye, face, body wall, limbs, trunk and heart.
(12) The differential scanning calorimetry (DSC) studies demonstrate an increased susceptibility of the Ala 183----Pro mutant to thermal denaturation.
(13) Mutants of Escherichia coli which require 5-aminolaevulinic acid (5-ALA), the first intermediate of haem biosynthesis, do not respond to haemin and porphyrins.
(14) The lipid-mobilizing activity of a synthetic peptide, NH2-Phe-Glu-Glu-Ala-Tyr-Ile-Pro-Lys-Glu-Gln-Lys-Tyr-Ser-Phe-COOH, corresponding to the 31-44 amino-acid sequence of human growth hormone, was studied.
(15) The replacements for Glu-43 (Asp, Gln, Asn, Ser, and Ala) both decreased the catalytic efficiency and changed the one- and two-dimensional NMR spectral properties of the mutant enzymes.
(16) Alas, for Jones, they found more of his ill-gotten gains in another plot he had perhaps forgotten to mention.
(17) The structures of two crystal forms of Boc-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-OMe have been determined.
(18) Daily intra-VTA injections of the mu opioid agonist Tyr-D-Ala-Gly-NMe-Phe-Gly-ol enhanced the behavioral stimulant effect of acute morphine.
(19) The (beta-chloro-, (beta, beta-dichloro-, and (beta, beta, beta-trichloro-alpha-aminoethyl)phosphonic acids have been synthesized and their inhibitory properties on the alanine racemases [EC 5.1.1.1] and the D-Ala:D-Ala ligases [EC 6.3.2.4] from Pseudomonas aeruginosa and Streptococcus faecalis have been evaluated.
(20) Angiotensin converting enzyme activity was measured in intact aortic rings utilizing the synthetic tripeptide [3H]-benzoyl-Phe-Ala-Pro as the substrate.
Regret
Definition:
(v.) Pain of mind on account of something done or experienced in the past, with a wish that it had been different; a looking back with dissatisfaction or with longing; grief; sorrow; especially, a mourning on account of the loss of some joy, advantage, or satisfaction.
(v.) Dislike; aversion.
(v. t.) To experience regret on account of; to lose or miss with a sense of regret; to feel sorrow or dissatisfaction on account of (the happening or the loss of something); as, to regret an error; to regret lost opportunities or friends.
Example Sentences:
(1) "We absolutely regret the setbacks Kim Dotcom has had since MegaUpload was taken offline, but we hope he as an entrepreneur will understand our side of the story and the decisions deliberately taken."
(2) Whilst we deeply regret all these incidents and acknowledge that the care of these patients could have been better, this is a relatively low number of incidents for a hospital of this size,” it said in a statement.
(3) The local MP, Rory Stewart, a mover and shaker on the broadband project, told me that he was desperate to get telehealth into Cumbria, but regretfully felt that it was not immediately doable, because the local council and healthcare community did not yet have the necessary expertise.
(4) An innovative approach to treatment planning is described in which a planned dose distribution is evaluated in terms of prescribed limits of acceptability, and any discrepancies (referred to as "regions of regret") are displayed in the form of a contour diagram in which colors are used to represent different types and degrees of regret.
(5) The allegations come weeks after Top Gear executives expressed regret over a remark made by Clarkson on the show's Burma special, broadcast in March.
(6) We deeply regret any instance which led to the Financial Ombudsman Service receiving incorrect or incomplete information from us.” Clydesdale is now reviewing all PPI complaints handled before August 2014 and will pay redress to any affected customers.
(7) The other example is of a woman who had a child who died at the age of 10 and expressed no regrets, but when questioned about whether she would have continued a pregnancy knowingly aware the baby would die in 10 years, the woman replied that she could not imagine how anyone could be so strong as to bear a child knowing the brevity of its life.
(8) She insists she has no regrets about dedicating herself to the man millions admired but few really got to know.
(9) Of the 28 parents who did not see the body, 17 subsequently stated their regret.
(10) In the prime minister's reply, he said it was with "enormous regret that I accept your resignation as the member of parliament for Corby and East Northamptonshire, a seat that had been Labour for 13 years before you.
(11) "We regret that Congress was forced to waste its time voting on a foolish bill that was premised entirely on false claims and ignorance," David Jenkins, an REP official, said in a statement.
(12) "We regret this decision by the Russian government," a senior Obama administration official said.
(13) These cases may represent a small percentage of the many sterilization operations that are performed each year, yet the fact that tubal sterilization is performed primarily on fit young women for "nonmedical" reasons makes it all the more important that women who will come to regret the procedure are identified and advised against it.
(14) "I regret that these things which are speculative and are not signed off on should be the source of discussion in other quarters."
(15) A woman accused of being the only surviving member of a murderous German neo-Nazi cell that remained undetected for over a decade, has broken her silence for the first time telling a court she was not involved in the planning or carrying out of the attacks but that she regretted failing to prevent them.
(16) "There was clearly inappropriate behaviour by some of the other guests and I deeply regret that this happened.
(17) The pair’s barrister, Charanjit Jutla, said both men were of good character and deeply regretted their conduct.
(18) He pointed out that Labour had not introduced such a radical examination in 1997, something he now regretted.
(19) Stewart surely sees himself as a future minister, though he regrets telling one journalist he wanted to be.
(20) Rupert Murdoch has said he regrets that his papers have turned against prime minister Gordon Brown – but believes they are right to do so.