(n.) The state or condition of being an albino: abinoism; leucopathy.
Example Sentences:
(1) The nucleotide sequences presented thus enable us to discriminate the tyrosinase gene from its related sequences and are invaluable for a gene diagnosis of oculocutaneous albinism.
(2) The presence of a ring-like figure in the centre of the fundus oculi may be regarded as an additional clinical sign of albinism of the fundus oculi.
(3) Resuscitation was significantly more often successful with the Bunegin-Albin catheter (six of nine dogs) than with either Sorenson catheter (zero of seven in both groups) or the Swan-Ganz RA port (one of seven).
(4) Based upon the finding of giant pigment granules in clinically normal skin of the patient's mother, the patient was diagnosed as a case of dyschromatosis universalis with X-linked ocular albinism.
(5) These findings suggest that there is a partial block in the distal eumelanin pathway in this form of albinism.
(6) Minimal pigment, a new type of oculocutaneous albinism (OCA), is described.
(7) Two female patients with familial diffuse fibrosing alveolitis associated with oculocutaneous albinism are presented.
(8) Several types of autosomal recessive oculocutaneous albinism (OCA) are associated with abnormal tyrosinase function and a generalized reduction in or absence of cutaneous and eye melanin.
(9) Amplitudes were reduced compared with those obtained with the sclera unoccluded, suggesting that responses to transscleral illumination contributed to the ERG in this type of albinism.
(10) On account of a recently developed tinnitus, a young woman with the characteristic features of Klein-Waardenburg's syndrome (impairment of hearing, partial albinism, telecanthus) was hospitalised.
(11) The introducer sheath was compared to a Sorenson CVP catheter, a Bunegin-Albin Air Aspiration CVP Catheter, and the proximal port of a pulmonary artery catheter.
(12) An 11-year-old boy had dyskeratosis congenita, elevated fetal hemoglobin level, X-linked ocular albinism, and juvenile-onset diabetes mellitus.
(13) A family was studied in which four siblings had oculocutaneous albinism.
(14) The broader category of mild to moderate hypopigmentation without all of the features of albinism may ultimately prove to be as important in understanding melanin metabolism.
(15) The absence of the foveolar pit and the decrease of visual acuity in tyrosinase-positive albinism is caused by definite morphologic alteration in the arrangement of ganglion cells in the macular region in the sense of a foveolar aplasia.
(16) Ocular albinism is distinguished from the more common oculocutaneous albinism by the presence of normal pigmentation of skin and hair in the former condition.
(17) The iris shows the lack of pigmentation in various types of albinism.
(18) It has recently been suggested that aberrant misrouting of retino-geniculate-cortical (RGC) projections, a finding previously noted only in albinism, may be an additional feature of the Prader-Willi syndrome.
(19) Histopathologic and ultrastructural findings in an eye from a patient with complete oculocutaneous albinism are reported.
(20) This is believed to be the first case of albinism reported in sheep.
Melanism
Definition:
(n.) An undue development of dark-colored pigment in the skin or its appendages; -- the opposite of albinism.
(n.) A disease; black jaundice. See Mel/na.
Example Sentences:
(1) In agreement with the InsP3 assays, phorbol ester (TPA) has no effect on melanization, tyrosinase activity or cell proliferation.
(2) These skins preserve the aspects and behaviour of normal human skin but after 1 month they have a heavy melanic hyperpigmentation.
(3) The skin is heavily pigmented with the epidermis, pilary canals, and the outer cell layer of the apocrine duct richly melanized.
(4) A ventrally localized melanization inhibiting factor (MIF) has been suggested to play an important role in the establishment of the dorsal-ventral pigment pattern in Xenopus laevis [Fukuzawa and Ide:Dev.
(5) The processes of melanosome maturation in the late-melanizing goldfish are evident from these observations.
(6) Melanin granules inside keratinocytes were fully melanized.
(7) Melanization in vivo, and in vitro, due to a polyphenoloxidase released by the blood cells, was stimulated by the presence of the fungal cell wall surface.
(8) The endogenous norepinephrine level was increased in eyes with melanic pigments and the exogenous amine uptake was decreased.
(9) The data suggest that host endocrines are involved in the encapsulation and melanization reactions of the larvae, but the nature of the involvement is not known.
(10) These findings suggest that glutathione provides a new situation of interrupted melanogenesis in which melanization cannot proceed despite complete formation of melanosome matrix structure and a lack of inhibition of cellular metabolisms including protein glycosylation.
(11) Conidiogenous cells in both species developed melanin only within the lowermost part of the lateral walls while the other cells of the conidium were uniformly melanized around the circumference of the cell; melanin in these cells being deposited within, at least, half the width of the cell wall.
(12) These changes may indicate the gradual melanization of the lipopigments due to auto-oxidation of catecholamines.
(13) Depending on the dose or period of feeding, symptoms were cuticular melanization, swellings in intersegmental regions, cuticular lesions, rupture of the body wall, and death.
(14) Intracellular melanization, a defense or an immune response in the thoracic muscle cells, was investigated in a refractory strain of Anopheles quadrimaculatus infected with larvae of Brugia malayi.
(15) Difficulty encountered in resolving grains of exposed photographic emulsion in autoradiographs of the densely melanized retinal pigment epithelium was solved by using epi-polarized or incident light microscopy.
(16) Inhibition of tyrosine hydroxylase with alpha-methyl-p-tyrosine retarded growth and prevented melanization of limb regenerate in adult newts (Triturus cristatus).
(17) sinensis was 72.3%; the percentage of melanized microfilariae in young Cx.
(18) It is suggested that the surface of the parasite may have inhibitors against enzyme systems causing melanization.
(19) During melanization, oxidation products of tyrosine are generated which are toxic to the cells.
(20) The melanization response of adult female Aedes aegypti (black-eyed Liverpool strain) against intrathoracically inoculated Dirofilaria immitis microfilariae (mff) was assessed with transmission electron microscopy.