(n.) The state or condition of being an albino: abinoism; leucopathy.
Example Sentences:
(1) The nucleotide sequences presented thus enable us to discriminate the tyrosinase gene from its related sequences and are invaluable for a gene diagnosis of oculocutaneous albinism.
(2) The presence of a ring-like figure in the centre of the fundus oculi may be regarded as an additional clinical sign of albinism of the fundus oculi.
(3) Resuscitation was significantly more often successful with the Bunegin-Albin catheter (six of nine dogs) than with either Sorenson catheter (zero of seven in both groups) or the Swan-Ganz RA port (one of seven).
(4) Based upon the finding of giant pigment granules in clinically normal skin of the patient's mother, the patient was diagnosed as a case of dyschromatosis universalis with X-linked ocular albinism.
(5) These findings suggest that there is a partial block in the distal eumelanin pathway in this form of albinism.
(6) Minimal pigment, a new type of oculocutaneous albinism (OCA), is described.
(7) Two female patients with familial diffuse fibrosing alveolitis associated with oculocutaneous albinism are presented.
(8) Several types of autosomal recessive oculocutaneous albinism (OCA) are associated with abnormal tyrosinase function and a generalized reduction in or absence of cutaneous and eye melanin.
(9) Amplitudes were reduced compared with those obtained with the sclera unoccluded, suggesting that responses to transscleral illumination contributed to the ERG in this type of albinism.
(10) On account of a recently developed tinnitus, a young woman with the characteristic features of Klein-Waardenburg's syndrome (impairment of hearing, partial albinism, telecanthus) was hospitalised.
(11) The introducer sheath was compared to a Sorenson CVP catheter, a Bunegin-Albin Air Aspiration CVP Catheter, and the proximal port of a pulmonary artery catheter.
(12) An 11-year-old boy had dyskeratosis congenita, elevated fetal hemoglobin level, X-linked ocular albinism, and juvenile-onset diabetes mellitus.
(13) A family was studied in which four siblings had oculocutaneous albinism.
(14) The broader category of mild to moderate hypopigmentation without all of the features of albinism may ultimately prove to be as important in understanding melanin metabolism.
(15) The absence of the foveolar pit and the decrease of visual acuity in tyrosinase-positive albinism is caused by definite morphologic alteration in the arrangement of ganglion cells in the macular region in the sense of a foveolar aplasia.
(16) Ocular albinism is distinguished from the more common oculocutaneous albinism by the presence of normal pigmentation of skin and hair in the former condition.
(17) The iris shows the lack of pigmentation in various types of albinism.
(18) It has recently been suggested that aberrant misrouting of retino-geniculate-cortical (RGC) projections, a finding previously noted only in albinism, may be an additional feature of the Prader-Willi syndrome.
(19) Histopathologic and ultrastructural findings in an eye from a patient with complete oculocutaneous albinism are reported.
(20) This is believed to be the first case of albinism reported in sheep.
Vitiligo
Definition:
(n.) A rare skin disease consisting in the development of smooth, milk-white spots upon various parts of the body.
Example Sentences:
(1) Six patients with spreading vitiligo treated with applications of monobenzone developed a vesicular dermatitis.
(2) Duplicate heparinized blood samples were drawn from 22 subjects; 2 healthy subjects, 1 vitiligo and 19 with thyroid or parathyroid diseases.
(3) Jackson said he suffered from vitiligo, a condition that causes the skin to lose its pigment.
(4) Three patients with malignant melanoma and coexisting vitiligo are described.
(5) Two vitiligo patients were hypergastrinaemic suggesting latent pernicious anaemia.
(6) The psoralen analogs 8-methoxypsoralen (8-MOP) and 4,5',8-trimethylpsoralen (TMP), in combination with ultraviolet light (UVA, 320-400 nm), are potent modulators of epidermal cell growth and differentiation and are commonly used in photochemotherapy of psoriasis and vitiligo.
(7) Since persons with the Down syndrome are predisposed to immunological deficiency in thymus-dependent (T-cell) function, findings from the skin examinations suggest that immunologic factors might contribute to the increased incidence of vitiligo and alopecia areata seen in the Down syndrome.
(8) Association with diseases such as diabetes, vitiligo and hypothyroidism have strengthened the auto-immune nature of this syndrome.
(9) The results of the present study suggest that systemic factors may play a role in the pathogenesis of vitiligo and acquired hypomelanosis guttata.
(10) Psycho- and autonomotropic drugs, acupuncture, and psychotherapeutic conversations were used for the correction of psychologic abnormalities in 49 vitiligo patients, presenting with impaired sociopsychological adaptation and autonomic imbalance.
(11) The data obtained suggest that kynurenine and serotonin pathways of tryptophan metabolism were intensified in vitiligo.
(12) The lysis of human melanocytes by vitiligo patients' sera by two different effector mechanisms provides direct support for the autoimmune hypothesis of human vitiligo.
(13) No significant differences in the results of several immunological examinations (E-RFC, EAC-RFC, EA-RFC, IF, IF-elution) came to light results suggest that the lymphocytes are probably not implied in the pathogenesisof vitiligo.
(14) In three men vitiligo-like skin changes, enlargement of liver and spleen and diffuse goitre (grade II) with increased TSH secretion developed within one to two years of their having started work in a factory producing paratertiary butylphenol.
(15) Vitiligo lesions themselves gave rise to unidentified dendritic cells that survived for 10-15 days without manifesting any growth.
(16) C4 typing by Western blot analysis showed the frequency of the C4A*Q0 allele in the vitiligo patient group to be close to normal.
(17) This culture system will be applied to investigate the basic pathophysiology of vitiligo and other various pigmentary dermatoses.
(18) Vitiliginous achromia with malignant melanoma shows some discrepancies with vitiligo.
(19) A 45 year old Saudi male with poliosis, alopecia areata, vitiligo, anterior uveitis, inflammatory changes in the posterior pole of the retina and paraparesis presented with features of the Vogt-Koyanagi-Harada syndrome, uncontrolled diabetes mellitus and hypothyroidism.
(20) A diabetic patient is described presenting psoriasis, necrobiosis lipoidica diabeticorum, granuloma annulare, and vitiligo and with a history of recurrent erysipelas and mycotic infections.