(n.) One of a class of caustic bases, such as soda, potash, ammonia, and lithia, whose distinguishing peculiarities are solubility in alcohol and water, uniting with oils and fats to form soap, neutralizing and forming salts with acids, turning to brown several vegetable yellows, and changing reddened litmus to blue.
Example Sentences:
(1) Significant amounts of 35S-labeled material were lost during the alkali treatment.
(2) The results also suggest that both alkali metals most probably have been delivered to the suckling pups and some of their toxic effect was retarded.
(3) Rabbits eating Rabbit Chow excreted a very alkaline urine, but rats eating the same diet excreted much less alkali when expressed per kilogram of body weight.
(4) From these findings it is concluded that cardiac performance and carbohydrate metabolism are accelerated in alkali and depressed in acid perfusion, and that myocardial metabolism could be affected by pH not only secondary to the change of performance but also by itself.
(5) Electrophoresis, Sephadex chromatography, and ultrafiltration studies showed that the alkali-soluble, water-soluble cell wall antigen is comprised of lipid, polysaccharide, and protein and has a molecular weight range of 30,000 to 50,000.
(6) [Na+],[Cl-)and[alkali]were determined in the alkaline gastric juice samples (pH greater than 7.0).
(7) Plants placed in pure acid and alkali solutions were also able to neutralize the medium.
(8) TFP produced a more discrete block in the repair of alkali-labile lesions in DNA.
(9) Activation of GV by monochromatic 450-nm radiation causes two specific DNA changes in human P3 cells in culture as shown by alkaline elution techniques: single-strand breaks (i.e., alkali-labile sites plus frank strand scissions) and DNA-to-protein covalent bond crosslinks.
(10) Keratan sulphate was isolated from bovine intervertebral disc and bovine nasal septum after hydrolysis with proteinases and treatment with dilute alkali.
(11) It was necessary to avoid CsCl banding of procapsids in their preparation as this treatment altered both their pI and their sensitivity to alkali dissociation into 14S subunits.
(12) In these muscles, two kinds of mRNA for the cardiac myosin alkali light chain, identical with those in ventricular muscle, were expressed and their relative amount in each tissue was almost the same as that in ventricular muscle.
(13) The enzymes were detected and characterized by agarose gel electrophoresis of alkali-denatured digestion products.
(14) The alkali cations selectivity sequence induced by ETH1811 is Li+ (1) greater than Na+ (0.08) greater than K+ (0.02) greater than Cs+ (0.008).
(15) When the monomer was further dissociated into constituent subunits in strong alkali or at high concentrations of SDS, the CD spectrum disappeared almost completely, indicating loss of the asymmetric interactions of the chromophoric heme a with its immediate environments, consisting of the subunit assembly.
(16) Addition of alkali to the culture media results in decrease of cell GAD activity, whereas increase of enzyme level occurs only in cells growing in unbuffered media.
(17) Chain breaks as measured in alkali were also measured and found to be enhanced by the dye; the ratio of breaks per iodine loss was 0.9.
(18) Alkali hydrolysates of elastins contained a radioactive peak that was eluted between proline and leucine.
(19) Under limiting concentration conditions, BLM and NCS induce alkali-labile sites in DNA without a subsequent cleavage of the chain.
(20) Hydrolysis with mild alkali yields anhydroretinol, as it does for synthetic retinyl phosphate, with absorption maxima at 388, 368, and 346 nm.
Lithium
Definition:
(n.) A metallic element of the alkaline group, occurring in several minerals, as petalite, spodumene, lepidolite, triphylite, etc., and otherwise widely disseminated, though in small quantities.
Example Sentences:
(1) Thirteen patients with bipolar affective illness who had received lithium therapy for 1-5 years were tested retrospectively for evidence of cortical dysfunction.
(2) The present study was therefore carried out to specify further which type of adrenoceptor is involved in lithium-induced hyperglycaemia and inhibition of insulin secretion.
(3) Since 1979, patients started on long-term lithium treatment at the Psychiatric Hospital in Risskov have been followed systematically with recording of clinical and laboratory variables before the start of treatment, after 6 and 12 months of treatment, and thereafter at yearly intervals.
(4) Furthermore, recent investigations into the pharmacokinetics of lithium salts are dealt with.
(5) This suggested that some of the cell population became metabolically inactive at a very early stage, possibly owing to suboptimal conditions of growth.Glycine, lysozyme and lithium chloride initiated lysis of BCG growth in the aforementioned media 24-48 hours after inoculation.
(6) The ability of myo-inositol to reverse behavioral effects of lithium was tested using chronic inositol administration or acute intracerebroventricular (i.c.v.)
(7) Patients were examined before and 12 days after the beginning of lithium treatment.
(8) Safety is increased through temporary discontinuation or dosage reduction of lithium in special risk situations.
(9) This documents the inhibitory role which lithium can play in several examples of animal aggressive behavior including pain-elicited aggression, mouse killing in rats, isolation-induced aggression in mice, p-chlorophenylalanine-induced aggression in rats, and hypothalamically induced aggression in cats.
(10) Thirty-six investigations were made using a number of lithium fluoride micro-rods for each investigation.
(11) This study raises the possibility of lithium carbonate use as an adjunct in the treatment of amphetamine addiction.
(12) Although GTP most potently inhibited [125I]beta h-endorphin binding in the presence of sodium, inhibition of [125I]beta h-endorphin binding by GTP was also observed in the presence of the monovalent cations lithium and potassium, but not the divalent cations magnesium, calcium, or manganese.
(13) It was observed that the circadian rhythm was disrupted by injections of lithium at the beginning of the light as well as the dark phase of the LD cycle.
(14) The comparative usefulness of carbamazepine and lithium carbonate in the acute and prophylactic management of DSM-III diagnosed major affective, schizoaffective, or schizophreniform psychoses was investigated in a 3-year, prospective double-blind randomized trial with 83 in- and outpatients.
(15) While continuing to receive antidepressant medication after the 21 day period, four of the patients then received lithium carbonate, and three received placebo.
(16) The decomposition of nitrosourea is facilitated when a proton or lithium ion is positioned at the oxygen of the nitroso group.
(17) A 51-year-old manic woman who developed acute severe lithium intoxication with neurotoxicity and nephrotoxicity during rapid abatement of manic episode was reported.
(18) The authors expressed in 1984 the assumption that lithium is the drug of the phenomenon of suicidal action in affective disorders.
(19) 20 female manic-depressive out-patients who had been treated with lithium over a long period (average time = 4.3 years), were submitted to a psychoanalytic interview and a personality test (FPI).
(20) The latter compounds were reduced with lithium aluminium hydride to the respective amines (II a-c) and then N-alkylated by reaction with 2-propynyl-, 2-butynyl- or 2,3-butadienyl bromides to the corresponding amines (III a-j).