(v. t.) To convert into an alkali; to give alkaline properties to.
(v. i.) To become changed into an alkali.
Example Sentences:
(1) The number of viable cells decreased as well as the ability to evolve oxygen, to produce C-4 compounds, and to react to pH changes by liberating acids upon alkalifying or neutral products upon acidifying.
Basify
Definition:
(v. t.) To convert into a salifiable base.
Example Sentences:
(1) The procedure involved extraction of the compounds and the internal standard nitrazepam from basified plasma with dichloromethane and chromatography on a C18 column (microBondapak, 300 X 3.9 mm I.D.)
(2) Reductive destruction of drugs was accomplished by mixing each solution with an equal volume of 1 M potassium hydroxide solution and adding 1 g of nickel-aluminum alloy for each 20 mL of basified solution.
(3) Oxpentifylline, metabolites and internal standards are extracted from basified plasma or urine with chloroform and the metabolites are converted to their O-trifluoroacetates before analysis by capillary gas chromatography using nitrogen-selective detection.
(4) Sufentanil was extracted from basified fluids and tissue homogenates with hexane:ethanol (19:1).
(5) The analytical procedure involved extraction of the compound and its internal standard from basified plasma with n-butyl chloride-dichloromethane and chromatography of the extract on a DB-5 fused-silica column (30 m X 0.25 mm I.D.
(6) Seven major radioactive components were detected in the chloroform extract of basified rat urine and five major components in similar extracts of human urine.
(7) Sulforidazine-5-sulfoxide metabolites were then extracted from the same basified plasma using a second solvent mixture consisting of methylene chloride, pentane and 2-propanol.
(8) Sulforidazine was first extracted from basified plasma using a mixture of pentane and 2-propanol.
(9) The hydrochloric acid phase is basified, and the amphetamines and the internal standard benzylamine are derivatized with pentafluorobenzenesulfonyl chloride prior to analysis on a gas chromatograph equipped with a capillary column.
(10) Tiamenidine and internal standard are extracted from basified plasma, converted to dibenzyl derivatives by reaction with benzyl bromide and potassium t-butoxide in the presence of 18-crown-6 ether prior to analysis by selected ion monitoring.
(11) After addition of the internal standard, plasma samples were basified with phosphate buffer (pH 9.0) and extracted with a mixture of cyclohexane-dichloromethane.
(12) Employing an ethoxy analogue as internal standard, the two compounds were extracted from basified plasma using dichloromethane.
(13) Each organic extract was subsequently back-extracted separately with 0.1 M hydrochloric acid, basified and re-extracted with the original solvent mixtures.
(14) After a single-step extraction from basified samples with dichloromethane, using decarboxyloflazepate as an internal standard, samples were analysed using a reversed-phase Nova Pak 5-microns column with a mobile phase of methanol - phosphate buffer (60 + 40) adjusted to pH 7.6.
(15) DMP is extracted from the plasma after basifying with dichloromethane.
(16) The formation of silver oxide in basified colloids may facilitate borate adsorption.
(17) The organic extract, basified with tetramethylammonium hydroxide, in evaporation tube was evaporated to dryness at 30 degrees C under nitrogen.
(18) The robotic system aliquots the biological sample, adds the internal standard (CGP 23901) and pH 12 buffer, extracts the compounds from the basified matrix into an organic phase (methyl-t-butyl ether:dichloromethane, 2:1) and concentrates the extracts for reversed-phase, high performance liquid chromatographic (HPLC) analysis.
(19) MDL 201,012 (I), diethyl-MDL 201,012 (internal standard, II) and desmethyldiol-MDL 201,012 (masking agent, III) were isolated from basified plasma (2 mL) by solid phase extraction using Bond-Elut C-18 cartridges.
(20) In both techniques, deproteinized and basified plasma samples were extracted and purified by adsorption on an Extrelut-1 column, then the drug was eluted with dichloromethane.