(a.) Of or pertaining to an alkali or to alkalies; having the properties of an alkali.
Example Sentences:
(1) Serum gamma glutamyl transferase (gammaGT) and alkaline phosphatase (ALP) activities have been estimated in 49 epileptic patients taking anticonvulsant drugs.
(2) N-Ethylmaleimide-sensitive 5'-nucleotide phosphodiesterase and alkaline phosphatase activities from other cell lines were also recovered in the cytosol.
(3) Alkaline borohydride treatment released over 95% of the oligosaccharide units in pool I and approximately 30% of the oligosaccharide units in pool III.
(4) Since alkaline phosphatase, a glycoprotein, is not affected, the destruction is selective and presumably involves only the most exposed membrane components.
(5) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(6) The following alterations in liver function tests are associated with phenytoin hepatotoxicity: elevations in serum aminotransferases, lactic dehydrogenase, alkaline phosphatase, bilirubin, and prothrombin time.
(7) Azocoupling of the alkaline phosphatase with diazonium-1-H-tetrazole and Zn2+ content measurement of azocoupled enzyme probes indicated that 2 histidine residues per subunit are involved in binding of the catalytically important Zn2+.
(8) In-vivo data are limited primarily to dominant lethal studies in rats and some in-vivo alkaline elution results.
(9) S-lactic dehydrogenase (s-LDH), SGOT, and s-alkaline phosphatase were found to be too unspecific to indicate liver metastases unless all three tests were normal or abnormal.
(10) The increased release of alkaline phosphatase from the particulate matrix by lysophosphatidylcholine was confirmed by disc electrophoresis.
(11) Characterization of the components released by alkaline hydrolysis indicated that O-glycosylated hydroxylysine residues are nonenzymatically N-glycated to the same extent as those without an enzymatically attached carbohydrate unit.
(12) The presence of alkaline phosphatase-positive cells forming woven bone in giant cell granulomas suggests that osteoblasts are present in the lesion.
(13) Under the influence of PSC, parathyroid gland function remained unchanged, but serum levels of bone alkaline phosphatase and osteocalcin were low, and urinary hydroxyproline was high.
(14) At alkaline pH, the Schiff's base equilibrium can be continuously and specifically displaced by reduction in situ with sodium cyanohydridoborate, which on the other hand leaves intact the reacting aldehyde groups of oxidized tRNA.
(15) Rabbits eating Rabbit Chow excreted a very alkaline urine, but rats eating the same diet excreted much less alkali when expressed per kilogram of body weight.
(16) Conclusions derived from these studies are: 1) The model used is a valid means of studying in vivo luminal disappearance of PLP in the rat jejunum; 2) a major portion of the disappearance seems to involve hydrolysis by alkaline phosphatase; 3) a significant portion of this hydrolysis occurs intraluminally; and 4) a second mechanism of PLP disappearance, which is nonphosphatase-mediated, also appears operative and may represent absorption of the intact, phosphorylated vitamin.
(17) Urinary excretion of hydroxyproline fell significantly in patients receiving ND, whereas the biochemical indices of bone formation did not change (alkaline phosphatase) or increased (osteocalcin; P less than 0.01).
(18) Serum levels of lactate dehydrogenase and alkaline phosphatase were considerably elevated in shell-less embryos.
(19) An observed differential distribution of alkaline and acid phosphatase on the surfaces of growing bones may serve to describe transformative processes of bone growth.
(20) Alkaline treatment of 4, 5, 18, and 19 gave the corresponding adenosine 5'-(hydroxycarbonyl)phosphonate (14), guanosine 5'-(hydroxycarbonyl) phosphonate (15), 2'-deoxyadenosine 5'-(hydroxycarbonyl)phosphonate (20), and 2'-deoxyguanosine 5'-(hydroxycarbonyl) phosphonate (21).
Saline
Definition:
(a.) Consisting of salt, or containing salt; as, saline particles; saline substances; a saline cathartic.
(a.) Of the quality of salt; salty; as, a saline taste.
(a.) A salt spring; a place where salt water is collected in the earth.
(n.) A crude potash obtained from beet-root residues and other similar sources.
(n.) A metallic salt; esp., a salt of potassium, sodium, lithium, or magnesium, used in medicine.
Example Sentences:
(1) All rats were examined in the conscious, unrestrained state 12 wk after induction of diabetes or acidified saline (pH 4.5) injection.
(2) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(3) The third route was quantitated by its sensitivity to probenecid and its activity was increased in saline buffers and upon addition of glucose and was inhibited by oligomycin.
(4) Naloxone injection into those rats exposed to constant illumination significantly increased hypothalamic levels of beta-endorphin compared to saline injected controls.
(5) "Acoustic" craters were produced by two laser pulses delivered into a saline-filled metal fiber cap, which was placed in a mechanically drilled crater.
(6) Differences between the albino vs pigmented strains were observed following injections of saline.
(7) The purpose of this study was to determine the effect of pretreatment with indomethacin on the refractory period to hypertonic saline-induced bronchoconstriction.
(8) When caffeine evokes a contraction, and only then, crayfish muscle fibers become refractory to a second challenge with caffeine for up to 20 min in the standard saline (5 mM K(o)).
(9) Hypertonic saline infusion induced significant (P less than 0.05) increases in serum Na and Cl concentrations and osmolality, whereas ISS induced a significant increase in serum Cl concentration and a significant decrease in serum phosphorus concentration.
(10) In a double-blind trial, 50 patients with subcostal incisions performed for cholecystectomy or splenectomy, received 10 ml of either 0.5% bupivacaine plain or physiological saline twice daily by wound perfusion through an indwelling drainage tube for 3 days after operation.
(11) Guanabenz is acutely natriuretic and diuretic in saline expanded animals.
(12) G-17-I infusion, the stomach was continuously infused with isotonic saline.
(13) From comparative in vitro tests in air, fat, water, and saline it was concluded that only tests in fat or air represent the worst case condition after implantation.
(14) Different groups of animals received 3 doses of 10 ng LH-RH or saline prior to a single 50 ng LH-RH injection.
(15) Saline-injected controls started gathering the pups immediately and usually showed all elements of maternal behaviour within 10 min.
(16) The CI treatment induced almost full protection against these behavioral effects of saline stress but DS treatment was ineffective.
(17) Halothane variably increased the current produced (and therefore the estimated oxygen tension) at all polarizing voltages in saline solution equilibrated with either N2 or air.
(18) Liquid-dominated hydrothermal reservoirs, which contain saline fluids at high temperatures and pressures, have a significant potential for contamination of the environment by heavy metals.
(19) Ultrasound diagnosis could be aided by transabdominal amnio-infusion and, if necessary, fetal intraperitoneal saline installation.
(20) But for the mid Atlantic, the models showed that only human-driven global warming could explain the increase in saltiness – the first time such an explicit link has been made between climate change and salinity.