(n.) An organic base, especially one of a class of substances occurring ready formed in the tissues of plants and the bodies of animals.
Example Sentences:
(1) Thus, alkaloid and insecticide modifications share many features but differ in how much the conducting properties of the pore are changed and whether the channel can close reversibly while the toxin remains bound.
(2) A clear structure-mutagenicity relationship was observed in a series of aporphine alkaloids (aporphine, dehydroaporphine, 7-oxoaporphine and 4,5-dioxoaporphine), and 10,11-non-substituted aporphines were suggested to exert their mutagenicity through metabolic activation of the 10,11 positions, possibly as the 10,11-epoxides.
(3) A radioactive, photoactive Vinca alkaloid, N-(p-azido-[3,5-3H]-benzoyl)-N'-beta-aminoethylvindesine [( 3H]NABV) with pharmacological and biological activities similar to vinblastine was synthesized and used to identify specific Vinca alkaloid macromolecular interactions in calf brain homogenate by photoaffinity labeling.
(4) The comparative metabolism of the pyrrolizidine alkaloid (PA) senecionine was studied in vitro in incubations of rat, guinea pig, cow, horse, and sheep hepatic microsomes.
(5) They also displayed negative correlation between activities of protein-inhibitors and the total content of protein and alkaloids.
(6) Methods have been reviewed for alkylating agents, platinum compounds, antitumour antibiotics, antimetabolites, alkaloids, suramin, 1-hydroxy-3-amino-propylidene-1,1-bisphosphonate and tamoxifen.
(7) The resistant strains exhibited cross resistance to anthracycline antibiotics, vinca alkaloids, actinomycin D, colchicine.
(8) In mice treated with cepharanthine (Cepha), a biscoclaurine alkaloid, the number of T cells was increased in the parathymic lymph nodes (PtLNs) which are considered to be the specialized lymph nodes in local differentiation of T cells.
(9) The alkaloid tubulosine inhibits the process of peptide chain elongation by eukaryotic polysomes by specifically preventing the elongation-factor-2-dependent step of translocation.
(10) Cultured roots of Stephania cepharantha, which are rich sources of bisbenzylisoquinoline alkaloids, were fed 14C-labelled tyrosine, tyramine or dopamine.
(11) As a possible mechanism underlying the alterations of DRP, the functional consequences of atrophic changes of primary central afferent terminals are being discussed in terms of the close correlation between structure and function and the possible inferences of the electrophysiological reaction to the therapeutic application of Vinca alkaloids in the iontophoretic treatment of chronic intractable pain.
(12) The poisonous principles in tansy ragwort are pyrrolizidine alkaloids, which cause gradual alteration and necrosis of liver cells with replacement by fibrous tissue.
(13) In this study, the roots of Tabernaemontana heyneana Wall were examined and the isolation and identification of additional indole alkaloids and some pharmacological properties of coronaridine are described.
(14) The area ratios of four alkaloids (tropacocaine, norcocaine, cis-cinnamoylcocaine, and trans-cinnamoylcocaine) to cocaine are calculated for each sample.
(15) The main drugs with specific action on migraine include ergot alkaloids (ergotamine, dihydroergotamine), agonists (sumatriptan) or partial agonists (methysergide) at a specific subtype of 5-HT1-like receptors, beta-adrenoceptor antagonists (propranolol, metoprolol), calcium antagonists (flunarizine) and anti-inflammatory agents (indomethacin).
(16) Effects of solution variables on the binding and self-association explain the wide variation of reported apparent binding constants for Vinca alkaloids to tubulin.
(17) The concomitance of five previously reported trans-2,5-dialkyl-pyrrolidines along with small amounts of the cis isomers and N-methyl analogues makes the venom of M. indicum the most qualitatively diverse blend of alkaloids reported from an ant to date.
(18) Strong enhancement of delayed-type hypersensitivity (DTH) was observed after treatment with the active cyclophosphamide (CY) derivative Z 7557 or the plant alkaloid VP-16 at the site of sensitization.
(19) A total alkaloid and two purified alkaloid extracts of Alangium Vitiense were revealed by our experimental screening to be oncostatic on L1210 leukemia and two other lymphoid neoplasias in Mice.
(20) Possible mechanisms underlying these effects of insecticides on alkaloid-dependent uptake are discussed in light of a qualitative model formulated from these results and previous biochemical and electrophysiological studies.
Serpentine
Definition:
(a.) Resembling a serpent; having the shape or qualities of a serpent; subtle; winding or turning one way and the other, like a moving serpent; anfractuous; meandering; sinuous; zigzag; as, serpentine braid.
(n.) A mineral or rock consisting chiefly of the hydrous silicate of magnesia. It is usually of an obscure green color, often with a spotted or mottled appearance resembling a serpent's skin. Precious, or noble, serpentine is translucent and of a rich oil-green color.
(n.) A kind of ancient cannon.
(v. i.) To serpentize.
Example Sentences:
(1) Non-occupational exposure of the population living in the vicinity of the serpentine mining and processing mill in Nasławice was assessed.
(2) In October 2013, for a group exhibition at London’s Serpentine Gallery , they published a report called Youth Mode: A Report on Freedom , one chapter of which was entitled “Normcore”.
(3) The rock consists essentially of the fibrous serpentine mineral chrysotile (asbestos) and platy serpentines.
(4) The Serpentine's Poetry Marathon talks last year gave us 47 men and 18 women, as did its Manifesto Marathon the previous year.
(5) A few details of their plans have been revealed including the indication of it being the Serpentine's lowest pavilion ever, with the roof barely 1.5 metres (5ft) off the ground.
(6) Serpentine vessels were well seen as flow voids against high signal cyst or tumor on T2-weighted images, but contrast-enhanced CT also demonstrated them.
(7) A Swiss, Hans-Ulrich Obrist, is the co-director of the Serpentine Gallery.
(8) We present a case of cerebral giant serpentine aneurysm (GSA) and propose a definition of GSA.
(9) This giant serpentine aneurysm is a rather rare disease.
(10) In 10 years, only one solo woman architect, Zaha Hadid, has sketched the Serpentine's garden tent.
(11) Multiple extremely low-intensity serpentine "flow void" signs, indicating afferent and efferent vessels, were observed within or around the tumor.
(12) But later came work as diverse as The Maybe (1995) featuring the actor Tilda Swinton lying in a glass vitrine in the Serpentine Gallery, in London; a melted silver dollar drawn into wire so thin it was as long as the Empire State Building is tall; the wrapping of Rodin's The Kiss in a mile of string; and a 40-minute video of Parker interviewing Noam Chomsky.
(13) Angiograms in each case revealed a distinctive serpentine vascular channel surrounded by an avascular area causing a "mass effect."
(14) Environmental factors: The drinking-water pool in northern California is contaminated with asbestos of the serpentine type, which is associated with mesothelioma of the peritoneum and carcinoma of the lung, gallbladder, and pancreas.
(15) A simple and effective method of temporary tarsorrhaphy, which is referred to as intermarginal serpentine temporary tarsorrhaphy, is presented.
(16) Two cases of serpentine supravenous hyperpigmentation developing in the area of fotemustine infusions are reported.
(17) In some macaque species, transcervical aspiration of the uterine contents carries a significant risk of disturbing the cervical milieu due to the serpentine nature of the cervix.
(18) Overseas, he designed the United Nations secretariat in New York, the Communist party headquarters in Paris and Serpentine gallery summer pavilion in Hyde Park, London.
(19) Turn another, and you gaze on the royal park with the glories of the Serpentine.
(20) That led to a commission from the Serpentine Gallery, and performances in Paris and Moscow.