(a.) Quite by one's self; apart from, or exclusive of, others; single; solitary; -- applied to a person or thing.
(a.) Of or by itself; by themselves; without any thing more or any one else; without a sharer; only.
(a.) Sole; only; exclusive.
(a.) Hence; Unique; rare; matchless.
(adv.) Solely; simply; exclusively.
Example Sentences:
(1) Combinations of maximum amounts of glucagon and the cyclic nucleotide did not produce a greater effect than either agent alone.
(2) Philip Shaw, chief economist at broker Investec, expects CPI to hit 5.1%, just shy of the 5.2% reached in September 2008, as the utility hikes alone add 0.4% to inflation.
(3) Recently, it has been shown that radiation therapy, alone or combined with chemotherapy, can be successful.
(4) Basing the prediction of student performance in medical school on intellective-cognitive abilities alone has proved to be more pertinent to academic achievement than to clinical practice.
(5) Arthrotomy with continuous irrigation appears to be more effective in decreasing long-term residual effects than arthrotomy alone.
(6) In addition, control experiments with naloxone, ethanol, or cigarette smoking alone were performed.
(7) Because it has been suggested that the lathyrogen, BAPN, may stimulate the release of proteases, the protease inhibitors Trasylol and epsilon-aminocaproic acid (EACA) were given alone or in combination to BAPN-treated rats.
(8) Cells (1 x 10(5)) were seeded in 12- x -75-mm tissue culture tubes and incubated with various doses of IL-1 beta, IL-1 alpha, TNF-alpha, and IFN-gamma, alone or in specific combinations, for 15 min, two, 12, 24, and 72 h. PGE concentrations in the media were measured by radio-immunoassay.
(9) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
(10) Exogenous administration of estrogen alone or combined with progesterone have been associated with increased plasma cortisol levels.
(11) Transmission electron microscopy demonstrated that these blebs were devoid of organelles and microvilli; scanning electron microscopy revealed that the blebs were highly wrinkled and more numerous than were the projections observed in tissue from animals treated with testosterone alone, or in tissue from unoperated controls.
(12) The combination of methotrexate and cyclosporin is significantly better than either alone in controlling GVHD.
(13) DTIC, BCNU and CCNU produced responses in 28% of patients, alone or in combination with each other.
(14) Malondialdehyde was undetectable in cerebrospinal fluid after subarachnoid placement of agarose alone, although it was present in similar amounts in all groups that received subarachnoid placement of OxyHb.
(15) Ketamine alone caused ataxia even in the lowest dose used.
(16) The phenylalanine model allows the rapid assessment of whole body and muscle protein turnover from plasma samples alone, obviating the need for measurement of expired air CO2 production or enrichment.
(17) Infusion of 1 unit of 25-HCC per hour for 6 hours induced an antiphosphaturia only when administered with 0.2 units of PTH per hour, while neither agent alone changed phosphate excretion.
(18) In keratinocyte lines immortalized by E7 alone, the p53 half-life was found to be similar to that in non-transformed cells; however, it decreased to approximately 1 h following supertransfection of an E6 gene.
(19) Renal arteriography is therefore alone capable of answering two primordial questions: "Must surgery be undertaken and when operating, what surgical tactics to adopt".
(20) When given chronically over 6 weeks the advantages of adding benserazide (50 mg kg-1 day-1) to levodopa (40 mg kg-1 day-1) were less marked and although more dopamine was present in the striatum than with levodopa given alone (200 mg kg-1 day-1) there was no evidence of any increase in its metabolites (HVA and DOPAC) and therefore of its turnover and utilisation.
Lonesome
Definition:
(superl.) Secluded from society; not frequented by human beings; solitary.
(superl.) Conscious of, and somewhat depressed by, solitude; as, to feel lonesome.
Example Sentences:
(1) On our approach march to K2 base camp, we crossed this wild, beautiful, lonesome and very powerful landscape.
(2) Along with Woody Guthrie and Lead Belly, he brought the music of the dirt farms, the sweat shops and the lonesome highways into America's – and later the world's – living room.
(3) Not least against opponents who did seem vulnerable when Sunderland committed Adnan Januzaj and Steven Pienaar forward in support of the rather lonesome Jermain Defoe, who had a total of 13 touches all game.
(4) His rides across Tehran carry him from penthouse to pavement, from the miserable teenage soldiers staking out a decadent party to the lonesome playboy adrift in his parents' apartment.
(5) His artwork for the band also included the lonesome-looking cow on the cover of Atom Heart Mother, the burning businessman on the sleeve of Wish You Were Here, and the giant pig flying over Battersea power station on the cover of Animals.
(6) As you age, your health and mobility may become impaired, so having the opportunity and the finances to get online makes life less lonesome.
(7) ITV intrigue: A surprising number of you have written to ask why Clive Tylsdley is all on his lonesome in the gantry tonight.
(8) He drew on his Cascades experiences in Dharma Bums , Lonesome Traveler and Desolation Angels , in which he wrote: “Those lazy afternoons, when I used to sit, or lie down, on Desolation Peak, sometimes on the alpine grass, hundreds of miles of snow-covered rock all around…” Those views look different today.
(9) Sometimes, Oldham looked like a callow teenager; at others, wild and woolly like a lonesome pilgrim.
(10) Over on a makeshift stage, Coz Fontenot sits stoically with his violin, singing in that high, lonesome, wonderfully timeless voice.
(11) The situation of the tumour patients is characterised by a feeling of lonesomeness and isolation within their social environment.
(12) BBC Worldwide has signed a first-look deal with Douglas's fledgling independent production company, Lonesome Pine, which she founded with Catherine Tate Show scriptwriter Aschlin Ditta.
(13) Fang Fang and I walked past old couples waltzing to Are You Lonesome Tonight?, weaved between the hawkers selling knock-off Louis Vuitton and Rolex, and past the shops selling the real things, and under a giant screen showing films of pandas and paddy fields.
(14) The company said highlights in 2016 included the rollout of a Zara range designed to mark the release of the Rolling Stones’ new album, Blue & Lonesome, and the Join Life collection, made with sustainable fabrics.
(15) They are followed by drug and alcohol addicts, by elderly and lonesome people, by the group of patients who threaten with suicide or who announce it, and finally as a last risk group, by those people who have failed at a first attempt.
(16) The vans I see day after day – busy delivering vegetables next door, groceries across the road, bringing books, clothes and fridges at the push of a button – are not lifelines but the harbingers of a colder, more lonesome world.
(17) It has graced the western for 25 years now, beginning with the epic Lonesome Dove and reappearing in The Missing , a pursuit western by Ron Howard; in the Coens’ neo-noir western No Country For Old Men; and in his own marvellous and strange directorial debut, set in the same brutal Tex-Mex borderlands, The Three Burials of Melquiades Estrada .
(18) So says Derek Duffy - is that when you're on your lonesome ownsome?
(19) This moment, to me, showed defeat in its most bitter, most lonesome form.
(20) This pitch-black affair starred Philip Seymour Hoffman as a lonesome schlub who makes nuisance phone-calls and Jon Lovitz as an employee whose suicide goes largely unnoticed by his indifferent co-workers.