(a.) Quite by one's self; apart from, or exclusive of, others; single; solitary; -- applied to a person or thing.
(a.) Of or by itself; by themselves; without any thing more or any one else; without a sharer; only.
(a.) Sole; only; exclusive.
(a.) Hence; Unique; rare; matchless.
(adv.) Solely; simply; exclusively.
Example Sentences:
(1) Combinations of maximum amounts of glucagon and the cyclic nucleotide did not produce a greater effect than either agent alone.
(2) Philip Shaw, chief economist at broker Investec, expects CPI to hit 5.1%, just shy of the 5.2% reached in September 2008, as the utility hikes alone add 0.4% to inflation.
(3) Recently, it has been shown that radiation therapy, alone or combined with chemotherapy, can be successful.
(4) Basing the prediction of student performance in medical school on intellective-cognitive abilities alone has proved to be more pertinent to academic achievement than to clinical practice.
(5) Arthrotomy with continuous irrigation appears to be more effective in decreasing long-term residual effects than arthrotomy alone.
(6) In addition, control experiments with naloxone, ethanol, or cigarette smoking alone were performed.
(7) Because it has been suggested that the lathyrogen, BAPN, may stimulate the release of proteases, the protease inhibitors Trasylol and epsilon-aminocaproic acid (EACA) were given alone or in combination to BAPN-treated rats.
(8) Cells (1 x 10(5)) were seeded in 12- x -75-mm tissue culture tubes and incubated with various doses of IL-1 beta, IL-1 alpha, TNF-alpha, and IFN-gamma, alone or in specific combinations, for 15 min, two, 12, 24, and 72 h. PGE concentrations in the media were measured by radio-immunoassay.
(9) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
(10) Exogenous administration of estrogen alone or combined with progesterone have been associated with increased plasma cortisol levels.
(11) Transmission electron microscopy demonstrated that these blebs were devoid of organelles and microvilli; scanning electron microscopy revealed that the blebs were highly wrinkled and more numerous than were the projections observed in tissue from animals treated with testosterone alone, or in tissue from unoperated controls.
(12) The combination of methotrexate and cyclosporin is significantly better than either alone in controlling GVHD.
(13) DTIC, BCNU and CCNU produced responses in 28% of patients, alone or in combination with each other.
(14) Malondialdehyde was undetectable in cerebrospinal fluid after subarachnoid placement of agarose alone, although it was present in similar amounts in all groups that received subarachnoid placement of OxyHb.
(15) Ketamine alone caused ataxia even in the lowest dose used.
(16) The phenylalanine model allows the rapid assessment of whole body and muscle protein turnover from plasma samples alone, obviating the need for measurement of expired air CO2 production or enrichment.
(17) Infusion of 1 unit of 25-HCC per hour for 6 hours induced an antiphosphaturia only when administered with 0.2 units of PTH per hour, while neither agent alone changed phosphate excretion.
(18) In keratinocyte lines immortalized by E7 alone, the p53 half-life was found to be similar to that in non-transformed cells; however, it decreased to approximately 1 h following supertransfection of an E6 gene.
(19) Renal arteriography is therefore alone capable of answering two primordial questions: "Must surgery be undertaken and when operating, what surgical tactics to adopt".
(20) When given chronically over 6 weeks the advantages of adding benserazide (50 mg kg-1 day-1) to levodopa (40 mg kg-1 day-1) were less marked and although more dopamine was present in the striatum than with levodopa given alone (200 mg kg-1 day-1) there was no evidence of any increase in its metabolites (HVA and DOPAC) and therefore of its turnover and utilisation.
Sole
Definition:
(n.) Any one of several species of flatfishes of the genus Solea and allied genera of the family Soleidae, especially the common European species (Solea vulgaris), which is a valuable food fish.
(n.) Any one of several American flounders somewhat resembling the true sole in form or quality, as the California sole (Lepidopsetta bilineata), the long-finned sole (Glyptocephalus zachirus), and other species.
(n.) The bottom of the foot; hence, also, rarely, the foot itself.
(n.) The bottom of a shoe or boot, or the piece of leather which constitutes the bottom.
(n.) The bottom or lower part of anything, or that on which anything rests in standing.
(n.) The bottom of the body of a plow; -- called also slade; also, the bottom of a furrow.
(n.) The horny substance under a horse's foot, which protects the more tender parts.
(n.) The bottom of an embrasure.
(n.) A piece of timber attached to the lower part of the rudder, to make it even with the false keel.
(n.) The seat or bottom of a mine; -- applied to horizontal veins or lodes.
(v. t.) To furnish with a sole; as, to sole a shoe.
(a.) Being or acting without another; single; individual; only.
(a.) Single; unmarried; as, a feme sole.
Example Sentences:
(1) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(2) In 2012, 20% of small and medium-sized businesses were either run solely or mostly by women.
(3) Mieko Nagaoka took just under an hour and 16 minutes to finish the race as the sole competitor in the 100 to 104-year-old category at a short course pool in Ehime, western Japan , on Saturday.
(4) Solely infectious waste become removed hospital-intern and -extern on conditions of hygienic prevention, namely through secure packing during the transport, combustion or desinfection.
(5) This suggested that carcinogen-induced error incorporation during DNA synthesis was restricted solely to the treatment of a deoxynucleotide template.
(6) Tests in which the size of the landmark was altered from that used in training suggest that distance is not learned solely in terms of the apparent size of the landmark as seen from the goal.
(7) Today the physician who treats women with emotional problems during menopause cannot function solely as a psychotherapist; he must deal with both their soma and psyche.
(8) Several oilseed and legume protein products were fed to rats as the sole source of dietary protein, and in blends with cereals for the determination of protein efficiency ratio (PER) and biological availability of amino acids.
(9) In contrast, newly formed secondary myotubes are short cells which insert solely into the primary myotubes by a series of complex interdigitating folds along which adhering junctions occur.
(10) "It's a very open question as to whether this will come," said a diplomat in Brussels, adding that Cameron could find himself in the lonely position of being the sole national leader urging a renegotiation.
(11) Considering those portions of the molecule that can be deleted without a loss of catalytic activity, one is left with a catalytic center of approximately 130 nucleotides that is solely responsible for the molecule's activity.
(12) A brevibacterium, strain TH-4, previously isolated by aerobic enrichment on the monocyclic monoterpenoid cis-terpin hydrate as a sole carbon and energy source, was found to grow on alpha-terpineol and on a number of common sugars and organic acids.
(13) The results showed that patients with and without GOR disease cannot be separated solely on the basis of the standard manometric test, even adopting more parameters besides the traditional DOS pressure measurement.
(14) The favorable prognosis is due solely to the fact that women with an IUD have far less negative antecedents and that the EP probably occurred due to impaired ciliary action, reversible when the IUD is removed.
(15) Phosphate appears to be incorporated solely into serine residues.
(16) In the medium to long term, sole primary treatment by tamoxifen delays more definitive therapy.
(17) In the patients with aplastic anaemia the iron flux was diminished, but never eliminated, demonstrating that the exchangeable compartment was not solely erythroblastic, but included non-erythroid transferrin receptors.
(18) Suction mammaplasty can be used as a sole technique in congenital asymmetry or in post-reduction enlargement or asymmetry.
(19) The presence of grouped microcalcifications as the sole indicator of malignancy was seen in 100% (seven of seven) of the patients in the 30-39-year age group, 64% (18 of 28) in the 40-49-year age group, 37% (11 of 30) in the 50-59-year age group, 30% (seven of 23) in the 60-69-year age group, and 23% (six of 26) in the 70-85-year age group.
(20) If you and your mother are joint tenants, when she dies you will become the sole owner of the whole property even if her will says that she is leaving her share to someone else.