(v. t.) To make otherwise; to change in some respect, either partially or wholly; to vary; to modify.
(v. t.) To agitate; to affect mentally.
(v. t.) To geld.
(v. i.) To become, in some respects, different; to vary; to change; as, the weather alters almost daily; rocks or minerals alter by exposure.
Example Sentences:
(1) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
(2) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(3) The various evocational changes appear to form sets of interconnected systems and this complex network seems to embody some plasticity since it has been possible to suppress experimentally some of the most universal evocational events or alter their temporal order without impairing evocation itself.
(4) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(5) Morphological alterations in the lungs of pheasants after prolonged high-dosage administration of bleomycin sulfate were studied by light and electron microscopy.
(6) Incubation with IFN alpha or IFN gamma for 24 h resulted in only modest cytokinetic alterations, and they did not modify the effects of FUra.
(7) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(8) In dorsoventral (DV) reversed wings at both shoulder or flank level, the motor axons do not alter their course as they enter the graft.
(9) Neither spermidine nor spermine (0.5 mM) significantly altered [Ca2+]i.
(10) In addition to the changes associated with blood group A, we also found a decrease in sugar content, alterations in other antigens, and changes in the levels of several glycosyltransferases in cancerous tissues.
(11) When the concentration of thrombin or fibrinogen was altered systematically, mu T and mup were found to mirror each other except when the fibrinogen concentration was increased at low thrombin concentrations.
(12) Arteries treated with atrial natriuretic peptide showed no alterations in relaxation or cGMP content after incubation with pertussis toxin.
(13) These results could be explained by altered tissue blood flow and a decreased metabolic capacity of the liver in obese subjects.
(14) The sequential histopathologic alterations in femorotibial joints of partial meniscectomized male and female guinea pigs were evaluated at 1, 2, 3, 6, and 12 weeks post-surgery.
(15) However, survival was closely related to the severity of the illness at the time of randomization and was not altered by shunting.
(16) Brain damage may be followed by a number of dynamic events including reactive synaptogenesis, rerouting of axons to unusual locations and altered axon retraction processes.
(17) Since the advance and return of sperm inside the tubes could facilitate the interaction of sperm with secretions participating in its maturation, the persistent infertility after vasectomy could be related to the contractile alteration that follows the excessive tubal distention.
(18) Sixteen patients (27%) manifested anomalies of the urinary tract: 12 had markedly altered kidneys, 8 of which were unilateral and ipsilateral to the diaphragmatic defect.
(19) Corticosterone (4 x 10(-5) M) did not alter the stimulation-evoked 3H-overflow at 1-30 Hz.
(20) The results show that the presence of histones does not alter the bimodal DNA binding process.
Charge
Definition:
(v. t.) To lay on or impose, as a load, tax, or burden; to load; to fill.
(v. t.) To lay on or impose, as a task, duty, or trust; to command, instruct, or exhort with authority; to enjoin; to urge earnestly; as, to charge a jury; to charge the clergy of a diocese; to charge an agent.
(v. t.) To lay on, impose, or make subject to or liable for.
(v. t.) To fix or demand as a price; as, he charges two dollars a barrel for apples.
(v. t.) To place something to the account of as a debt; to debit, as, to charge one with goods. Also, to enter upon the debit side of an account; as, to charge a sum to one.
(v. t.) To impute or ascribe; to lay to one's charge.
(v. t.) To accuse; to make a charge or assertion against (a person or thing); to lay the responsibility (for something said or done) at the door of.
(v. t.) To place within or upon any firearm, piece of apparatus or machinery, the quantity it is intended and fitted to hold or bear; to load; to fill; as, to charge a gun; to charge an electrical machine, etc.
(v. t.) To ornament with or cause to bear; as, to charge an architectural member with a molding.
(v. t.) To assume as a bearing; as, he charges three roses or; to add to or represent on; as, he charges his shield with three roses or.
(v. t.) To call to account; to challenge.
(v. t.) To bear down upon; to rush upon; to attack.
(v. i.) To make an onset or rush; as, to charge with fixed bayonets.
(v. i.) To demand a price; as, to charge high for goods.
(v. i.) To debit on an account; as, to charge for purchases.
(v. i.) To squat on its belly and be still; -- a command given by a sportsman to a dog.
(v. t.) A load or burder laid upon a person or thing.
(v. t.) A person or thing commited or intrusted to the care, custody, or management of another; a trust.
(v. t.) Custody or care of any person, thing, or place; office; responsibility; oversight; obigation; duty.
(v. t.) Heed; care; anxiety; trouble.
(v. t.) Harm.
(v. t.) An order; a mandate or command; an injunction.
(v. t.) An address (esp. an earnest or impressive address) containing instruction or exhortation; as, the charge of a judge to a jury; the charge of a bishop to his clergy.
(v. t.) An accusation of a wrong of offense; allegation; indictment; specification of something alleged.
(v. t.) Whatever constitutes a burden on property, as rents, taxes, lines, etc.; costs; expense incurred; -- usually in the plural.
(v. t.) The price demanded for a thing or service.
(v. t.) An entry or a account of that which is due from one party to another; that which is debited in a business transaction; as, a charge in an account book.
(v. t.) That quantity, as of ammunition, electricity, ore, fuel, etc., which any apparatus, as a gun, battery, furnace, machine, etc., is intended to receive and fitted to hold, or which is actually in it at one time
(v. t.) The act of rushing upon, or towards, an enemy; a sudden onset or attack, as of troops, esp. cavalry; hence, the signal for attack; as, to sound the charge.
(v. t.) A position (of a weapon) fitted for attack; as, to bring a weapon to the charge.
(v. t.) A soft of plaster or ointment.
(v. t.) A bearing. See Bearing, n., 8.
(n.) Thirty-six pigs of lead, each pig weighing about seventy pounds; -- called also charre.
(n.) Weight; import; value.
Example Sentences:
(1) The Wales international and Port Vale defender Clayton McDonald both admitted having sex with the victim, – McDonald was found not guilty of the same charge.
(2) Yet the Tory promise of fiscal rectitude prevailed in England Alexander had been in charge of Labour’s election strategy, but he could not strategise a victory over a 20-year-old Scottish nationalist who has not yet taken her finals.
(3) The previous year, he claimed £1,415 for two new sofas, made two separate claims of £230 and £108 for new bed linen, charged £86 for a new kettle and kitchen utensils and made two separate claims, of £65 and £186, for replacement glasses and crockery.
(4) They had allegedly agreed that Younous would not be charged with any crime upon his arrival there and that he would not be detained in Morocco for longer than 72 hours.
(5) I’m not in charge of it but he’s stood up and presented that, and when Jenny, you know, criticised it, or raised some issues about grandparent carers – 3,700 of them he calculated – he said “Let’s sit down”.
(6) But the wounding charge in 2010 has become Brown's creation of a structural hole in the budget, more serious than the cyclical hit which the recession made in tax receipts, at least 4% of GDP.
(7) Only those derivatives with a free amino group and net positive charge in the side chain were effective.
(8) Charge data from the target hospital showed a statistically significant reduction in laboratory charges per patient in the quarter following program initiation (P = 0.02) and no evidence for change in a group of five comparison hospitals.
(9) At a fixed concentration of nucleotide the effectiveness of elution was proportional to the charge on the eluting molecule.
(10) [125I]AaIT was shown to cross the midgut of Sarcophaga through a morphologically distinct segment of the midgut previously shown to be permeable to a cytotoxic, positively charged polypeptide of similar molecular weight.
(11) For retrospective action to be taken, and an FA charge to follow, the decision of the panel must be unanimous.” The match between the sides ended in acrimony and two City red cards.
(12) As a Native American I am pretty sensitive to charges of racism and white supremacy,” the Oklahoma congressman added.
(13) Under a revised deal most people are now being vetted on time, but charges for the service have had to rise from £12 and free vetting for volunteers, to £28 for a standard disclosure and £33 for an advanced disclosure.
(14) Four Dutch activists were charged in Murmansk this week under the law.
(15) Both polycations investigated reduced the negative surface charge of assay cells and enhanced in vitro infectivity of murine C-type viruses, but had no influence on leukemia-virus-induced XC cell syncytia formation.
(16) The charges against Harrison were filed just after two white men were accused of fatally shooting three black people in Tulsa in what prosecutors said were racially motivated attacks.
(17) The antibody-hapten profiles revealed that the DNCB-fed animalss contained predominatly IgG2 in their serum by the time of their initial bleedings, whereas sensitized animals still contained a considerable proportion of more acidic antibodies having marked charge heterogeneity.
(18) With the flat-fee system, drug charges are not recorded when the drug is dispensed by the pharmacy; data for charging doses are obtained directly from the MAR forms generated by the nursing staff.
(19) As calls grew to establish why nobody stepped in to save Daniel, it was also revealed that the boy's headteacher – who saw him scavenging for scraps – has not been disciplined and has been put in charge of a bigger school.
(20) The phenomenon can be ascribed to the decrease in charge density due to the incorporation of dodecyl alcohol into SDS micelles.