(v. t.) To make otherwise; to change in some respect, either partially or wholly; to vary; to modify.
(v. t.) To agitate; to affect mentally.
(v. t.) To geld.
(v. i.) To become, in some respects, different; to vary; to change; as, the weather alters almost daily; rocks or minerals alter by exposure.
Example Sentences:
(1) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
(2) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(3) The various evocational changes appear to form sets of interconnected systems and this complex network seems to embody some plasticity since it has been possible to suppress experimentally some of the most universal evocational events or alter their temporal order without impairing evocation itself.
(4) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(5) Morphological alterations in the lungs of pheasants after prolonged high-dosage administration of bleomycin sulfate were studied by light and electron microscopy.
(6) Incubation with IFN alpha or IFN gamma for 24 h resulted in only modest cytokinetic alterations, and they did not modify the effects of FUra.
(7) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(8) In dorsoventral (DV) reversed wings at both shoulder or flank level, the motor axons do not alter their course as they enter the graft.
(9) Neither spermidine nor spermine (0.5 mM) significantly altered [Ca2+]i.
(10) In addition to the changes associated with blood group A, we also found a decrease in sugar content, alterations in other antigens, and changes in the levels of several glycosyltransferases in cancerous tissues.
(11) When the concentration of thrombin or fibrinogen was altered systematically, mu T and mup were found to mirror each other except when the fibrinogen concentration was increased at low thrombin concentrations.
(12) Arteries treated with atrial natriuretic peptide showed no alterations in relaxation or cGMP content after incubation with pertussis toxin.
(13) These results could be explained by altered tissue blood flow and a decreased metabolic capacity of the liver in obese subjects.
(14) The sequential histopathologic alterations in femorotibial joints of partial meniscectomized male and female guinea pigs were evaluated at 1, 2, 3, 6, and 12 weeks post-surgery.
(15) However, survival was closely related to the severity of the illness at the time of randomization and was not altered by shunting.
(16) Brain damage may be followed by a number of dynamic events including reactive synaptogenesis, rerouting of axons to unusual locations and altered axon retraction processes.
(17) Since the advance and return of sperm inside the tubes could facilitate the interaction of sperm with secretions participating in its maturation, the persistent infertility after vasectomy could be related to the contractile alteration that follows the excessive tubal distention.
(18) Sixteen patients (27%) manifested anomalies of the urinary tract: 12 had markedly altered kidneys, 8 of which were unilateral and ipsilateral to the diaphragmatic defect.
(19) Corticosterone (4 x 10(-5) M) did not alter the stimulation-evoked 3H-overflow at 1-30 Hz.
(20) The results show that the presence of histones does not alter the bimodal DNA binding process.
Upset
Definition:
(v. t.) To set up; to put upright.
(v. t.) To thicken and shorten, as a heated piece of iron, by hammering on the end.
(v. t.) To shorten (a tire) in the process of resetting, originally by cutting it and hammering on the ends.
(v. t.) To overturn, overthrow, or overset; as, to upset a carriage; to upset an argument.
(v. t.) To disturb the self-possession of; to disorder the nerves of; to make ill; as, the fright upset her.
(v. i.) To become upset.
(a.) Set up; fixed; determined; -- used chiefly or only in the phrase upset price; that is, the price fixed upon as the minimum for property offered in a public sale, or, in an auction, the price at which property is set up or started by the auctioneer, and the lowest price at which it will be sold.
(n.) The act of upsetting, or the state of being upset; an overturn; as, the wagon had an upset.
Example Sentences:
(1) A series of hierarchical multiple regressions revealed the effects of Surgency, Agreeableness, Conscientiousness, Emotional Stability, and Intellect on evoking upset in spouses through condescension (e.g., treating spouse as stupid or inferior), possessiveness (demanding too much time and attention), abuse (slapping spouse), unfaithfulness (having sex with others), inconsiderateness (leaving toilet seat up), moodiness (crying a lot), alcohol abuse (drinking too much alcohol), emotional constriction (hiding emotions to act tough), and self-centeredness (acting selfishly).
(2) Mean run time and total ST time were faster with CE (by 1.4 and 1.2 min) although not significantly different (P less than 0.06 and P less than 0.10) from P. Subjects reported no significant difference in nausea, fullness, or stomach upset with CE compared to P. General physiological responses were similar for each drink during 2 h of multi-modal exercise in the heat; however, blood glucose, carbohydrate utilization, and exercise intensity at the end of a ST may be increased with CE fluid replacement.
(3) Treatment is therefore often palliative, and endoscopic modalities cause considerably less general upset to the patient than surgery, radiotherapy or chemotherapy.
(4) We interpreted these results within an attributional framework that emphasizes the salience of upsetting events within a social network.
(5) She stayed calm during the upsetting search that led to Cynthia, who turned out to be flaky, chain-smoking and white (played by Brenda Blethyn).
(6) Trump might say that is what he wants to happen but for us, that’s deeply upsetting,” says Moore, who sits on the board of the Center Against Sexual and Family Violence and expects the case to have a chilling effect on reports of abuse.
(7) We’re all very upset right now,” said Daniel Ray, 24, in his third year of the divinity master’s degree program.
(8) Al-Jazeera's coverage has also upset the authorities.
(9) Our observations lead us to think that effectively, an event during which an important emotional state is induced, by upsetting the immune equilibrium, could more predispose a child (in this case the first born) to the action of pathogens.
(10) The interview was a friendly, intense discussion about upsetting situations the subject faced.
(11) A fired-up Lleyton Hewitt just fell short in his bid to steer Australia to an upset victory in their Davis Cup doubles showdown with the United States.
(12) She [Plath] was very worried about it because she thought it was going to upset her mother.
(13) Diagnostic characteristics of RSDS are: spontaneous burning pain, hyperalgesia, vasomotor disturbances, exacerbations by emotional upset, occurrence either spontaneously or after minor injury, occasional spontaneous resolution, extension to other body parts, and relief by sympathetic denervation.
(14) Plenty of people felt embarrassed, upset, outraged or betrayed by the Goncourts' record of things they had said or had said about them.
(15) The territory is actualy reached by deep demographic and social upsettings and chemiotherapy used alone is not enough efficient to obtain a definitive decrease of the endemy or even to avoid, for a long time, a new increase.
(16) The amount he is being paid for three short columns a week would “only get you sandal wearers all upset” if revealed, he says.
(17) The CPS doesn't just have to consider the public interest in prosecuting individual cases, but also the more general public interest in being able to say potentially upsetting things without fear of prosecution.
(18) As with other selective serotonin reuptake inhibitors (SSRIs), the most common side effect is gastrointestinal upset, especially nausea.
(19) It's possible that it upsets her to think about the past, or perhaps, these days, she saves her animation for the times when she is holding a microphone and standing in front of a swollen, angry crowd.
(20) The conclusion from this, the first reported series on adjuvant Tamoxifen therapy for MBC, is that significant improvement in disease-free survival can be achieved with minimal upset to the patients.