(a.) Being or succeeding by turns; one following the other in succession of time or place; by turns first one and then the other; hence, reciprocal.
(a.) Designating the members in a series, which regularly intervene between the members of another series, as the odd or even numbers of the numerals; every other; every second; as, the alternate members 1, 3, 5, 7, etc. ; read every alternate line.
(a.) Distributed, as leaves, singly at different heights of the stem, and at equal intervals as respects angular divergence.
(n.) That which alternates with something else; vicissitude.
(n.) A substitute; one designated to take the place of another, if necessary, in performing some duty.
(n.) A proportion derived from another proportion by interchanging the means.
(v. t.) To perform by turns, or in succession; to cause to succeed by turns; to interchange regularly.
(v. i.) To happen, succeed, or act by turns; to follow reciprocally in place or time; -- followed by with; as, the flood and ebb tides alternate with each other.
(v. i.) To vary by turns; as, the land alternates between rocky hills and sandy plains.
Example Sentences:
(1) The rash presented either as a pityriasis rosea-like picture which appeared about three to six months after the onset of treatment in patients taking low doses, or alternatively, as lichenoid plaques which appeared three to six months after commencement of medication in patients taking high doses.
(2) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(3) But in 2017, to borrow another phrase from across the pond, there simply is no alternative.
(4) This modulation results from repetitive, alternating bursts of excitatory and inhibitory postsynaptic potentials, which are caused at least in part by synaptic feedback to the command neurons from identified classes of neurons in the feeding network.
(5) These authors, therefore, conclude that this modified surgical approach is a viable alternative to the previously described procedures for resistant metatarsus adductus.
(6) The possibility that both IL 2 production and IL 2R expression are autonomously activated early in T cell development, before acquisition of the CD3-TcR complex, led us to study the implication of alternative pathways of activation at this ontogenic stage.
(7) This is an easy, safe, and rapid alternative for the emergent treatment of superior vena caval syndrome.
(8) Core biopsy with computed tomography (CT) or ultrasound (US) guidance may be such an alternative, particularly when a spring-loaded firing device is used.
(9) In both experiments, Gallus males were placed on a commercial feed restriction program in which measured amounts of feed are delivered on alternate days beginning at 4 weeks of age.
(10) The method used in connection with the well known autoplastic reimplantation not only presents an alternative to the traditional apicoectomy but also provides additional stabilization of the tooth by lengthing the root with cocotostabile and biocompatible A1203 ceramic.
(11) While the majority of EU member states, including the UK, do not have a direct interest in the CAR, or in taking action, the alternative is unthinkable.
(12) Many examples are given to demonstrate the applications of these programs, and special emphasis has been laid on the problem of treating a point in tissue with different doses per fraction on alternate treatment days.
(13) Initiation of the alternative pathway by the cryptococcal capsule is characterized by a lag in C3 accumulation and the appearance of a limited number of focal initiation sites which resemble those observed when the alternative pathway is activated by zymosan and nonencapsulated cryptococci.
(14) In our efforts to explore alternative treatment regimens for multidrug-resistant tumors we have examined the sensitivity of MDR tumor cell lines to lymphokine activated killer (LAK) cells.
(15) Following treatment with reserpine or alternatively with a combination of phenothiazines (Randolektil, Majeptil) a drug-induced parkinsonoid reaction was provoked in rats.
(16) Review of the records of five patients with CPSE treated with radiologic occlusion procedures showed that these are suitable alternatives to surgery.
(17) Being the decision-making agent, the rehabilitee must therefore be offered typical situational fragments of a possible educational and vocational future, intended on the one hand to inform him of occupational alternatives and, on the other, to provide initial experience.
(18) This study suggests that the BD VACUTAINER agar slant is an acceptable alternative to the Septi-Chek system for routine blood cultures.
(19) Treatment failures tend to occur early in the course of follow-up, permitting easy identification of candidates for alternative therapeutic approaches.
(20) In view of many ethical and legal problems, connected in some countries with obtaining human fetal tissue for transplantation, cross-species transplants would be an attractive alternative.
Heteroclitic
Definition:
(a.) Alt. of Heteroclitical
Example Sentences:
(1) The first concerns precursor cells that give rise to lambda-bearing NP-specific antibodies with heteroclitic fine specificity.
(2) The data suggest that the humoral response to different epitopes of a protein antigen during the maturation of the immune response is a stochastic process leading to transient humoral immunodominance, enhancing Ab populations and heterocliticity, depending upon individual characteristics, either in outbred or inbred populations.
(3) The goal of these experiments has been to capitalize on the functionally distinct responses of heteroclitic CTL to cross-reactive Ag to explore the role of Ag in regulating CTL proliferation and lytic function.
(4) It is predicted that a combination of solid-phase competition assay with high epitope density and direct binding assay with low epitope density would result in optimal detection of heteroclitic antibodies and small differences in antibody affinity for cross-reactive antigens.
(5) By contrast, the heteroclitic Abs to eGH developed by hypopituitary patients therapeutically injected with human growth hormone failed to react with any eGH-derived fragment.
(6) m ABs 8 to 14 and 16 to 20 demonstrated heteroclitic behavior, that is, they bound CTT IIIa better than the immunogen CTT III.
(7) One assay method failed to detect heteroclitic activity of 1 antibody which was clearly evident in the other 3 assays.
(8) Moreover, some anti-BP mAbs and anti-Cop 1 mAbs reacted in a heteroclitic manner and favored the cross-reactive antigen over the immunogen.
(9) However, immunization with the heterologous peptide resulted in a response strictly directed to rat CII and the immunogen while immunization with the autologous peptide elicited T cells which reacted in a heteroclitic fashion, with a stronger response to the heterologous peptide than to the autologous peptide, and did respond to rat CII but not to mouse CII.
(10) Polypeptides (Lys-Ser-Glu)n induced cross-reacting or heteroclitic antibodies.
(11) Monoclonal and anti-dinitrophenyl and anti-trinitrophenyl IgE antibodies were used to measure heterocliticity using competitive inhibition assays with homologous and heterologous haptens.
(12) To our knowledge, this is the first description of a T cell clone that is specific for a class I antigen and cross-reacts heteroclitically with a class II antigen.
(13) A number of antibodies showed heteroclitic binding to particular insulin variants.
(14) Med., 146 (1977) 1323-1331), by comparing the encephalitogenic guinea pig sequence to a less potent analog, had also previously observed what now would be termed a heteroclitic phenomenon at the T cell level in Lewis rats.
(15) In this report, we employ a competition assay to confirm that this alloresponse involves a groove-binding peptide, demonstrate that this peptide derives from or depends on fetal calf serum and exploit a panel of antigen-presenting cell lines--each displaying an Ak complex with a different position 69 substitution--to establish that the alloresponse is not just a heteroclitic response to ribonuclease, itself.
(16) The results indicated temporal and individual variations in the titers of each class of Ab as well as the existence of enhancer and heteroclitic Ab.
(17) Products of both genes had an exotic (heteroclitic) fine-specificity.
(18) Although most of the animals showed cross-reacting Ab, two out of 12 mice, chronically injected, developed heteroclitic Ab.
(19) Heterocliticity towards non-human GH was also detected.
(20) Some of the antibodies could be inhibited to a greater degree with the cross-reacting haptens than with the haptens homologous to the immunizing antigen, therefore these antibodies were heteroclitic.