(1) The rash presented either as a pityriasis rosea-like picture which appeared about three to six months after the onset of treatment in patients taking low doses, or alternatively, as lichenoid plaques which appeared three to six months after commencement of medication in patients taking high doses.
(2) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(3) But in 2017, to borrow another phrase from across the pond, there simply is no alternative.
(4) This modulation results from repetitive, alternating bursts of excitatory and inhibitory postsynaptic potentials, which are caused at least in part by synaptic feedback to the command neurons from identified classes of neurons in the feeding network.
(5) These authors, therefore, conclude that this modified surgical approach is a viable alternative to the previously described procedures for resistant metatarsus adductus.
(6) The possibility that both IL 2 production and IL 2R expression are autonomously activated early in T cell development, before acquisition of the CD3-TcR complex, led us to study the implication of alternative pathways of activation at this ontogenic stage.
(7) This is an easy, safe, and rapid alternative for the emergent treatment of superior vena caval syndrome.
(8) Core biopsy with computed tomography (CT) or ultrasound (US) guidance may be such an alternative, particularly when a spring-loaded firing device is used.
(9) In both experiments, Gallus males were placed on a commercial feed restriction program in which measured amounts of feed are delivered on alternate days beginning at 4 weeks of age.
(10) The method used in connection with the well known autoplastic reimplantation not only presents an alternative to the traditional apicoectomy but also provides additional stabilization of the tooth by lengthing the root with cocotostabile and biocompatible A1203 ceramic.
(11) While the majority of EU member states, including the UK, do not have a direct interest in the CAR, or in taking action, the alternative is unthinkable.
(12) Many examples are given to demonstrate the applications of these programs, and special emphasis has been laid on the problem of treating a point in tissue with different doses per fraction on alternate treatment days.
(13) Initiation of the alternative pathway by the cryptococcal capsule is characterized by a lag in C3 accumulation and the appearance of a limited number of focal initiation sites which resemble those observed when the alternative pathway is activated by zymosan and nonencapsulated cryptococci.
(14) In our efforts to explore alternative treatment regimens for multidrug-resistant tumors we have examined the sensitivity of MDR tumor cell lines to lymphokine activated killer (LAK) cells.
(15) Following treatment with reserpine or alternatively with a combination of phenothiazines (Randolektil, Majeptil) a drug-induced parkinsonoid reaction was provoked in rats.
(16) Review of the records of five patients with CPSE treated with radiologic occlusion procedures showed that these are suitable alternatives to surgery.
(17) Being the decision-making agent, the rehabilitee must therefore be offered typical situational fragments of a possible educational and vocational future, intended on the one hand to inform him of occupational alternatives and, on the other, to provide initial experience.
(18) This study suggests that the BD VACUTAINER agar slant is an acceptable alternative to the Septi-Chek system for routine blood cultures.
(19) Treatment failures tend to occur early in the course of follow-up, permitting easy identification of candidates for alternative therapeutic approaches.
(20) In view of many ethical and legal problems, connected in some countries with obtaining human fetal tissue for transplantation, cross-species transplants would be an attractive alternative.
Direct
Definition:
(a.) Straight; not crooked, oblique, or circuitous; leading by the short or shortest way to a point or end; as, a direct line; direct means.
(a.) Straightforward; not of crooked ways, or swerving from truth and openness; sincere; outspoken.
(a.) Immediate; express; plain; unambiguous.
(a.) In the line of descent; not collateral; as, a descendant in the direct line.
(a.) In the direction of the general planetary motion, or from west to east; in the order of the signs; not retrograde; -- said of the motion of a celestial body.
(v. t.) To arrange in a direct or straight line, as against a mark, or towards a goal; to point; to aim; as, to direct an arrow or a piece of ordnance.
(v. t.) To point out or show to (any one), as the direct or right course or way; to guide, as by pointing out the way; as, he directed me to the left-hand road.
(v. t.) To determine the direction or course of; to cause to go on in a particular manner; to order in the way to a certain end; to regulate; to govern; as, to direct the affairs of a nation or the movements of an army.
(v. t.) To point out to with authority; to instruct as a superior; to order; as, he directed them to go.
(v. t.) To put a direction or address upon; to mark with the name and residence of the person to whom anything is sent; to superscribe; as, to direct a letter.
(v. i.) To give direction; to point out a course; to act as guide.
(n.) A character, thus [/], placed at the end of a staff on the line or space of the first note of the next staff, to apprise the performer of its situation.
Example Sentences:
(1) Direct fetal digitalization led to a reduction in umbilical artery resistance, a decline in the abdominal circumference from 20.3 to 17.8 cm, and resolution of the ascites within 72 h. Despite this dramatic response to therapy, fetal death occurred on day 5 of treatment.
(2) One hundred and twenty-seven states have said with common voice that their security is directly threatened by the 15,000 nuclear weapons that exist in the arsenals of nine countries, and they are demanding that these weapons be prohibited and abolished.
(3) However, when first trimester specimens were analyzed, the direct-product measurements were significantly larger than the corresponding 3H2O assay results.
(4) The generally accepted hypothesis is a coronary spasm but a direct cardiotoxicity of 5-FU cannot be.
(5) One hour after direct mechanical cardiomassage (DMCM) a moderately pronounced edema of the intercellular spaces in the basal compartment of the seminiferous epithelium, normal content of lactate and succinate dehydrogenases, and a certain decrease in the activity of glucose-6-phosphate dehydrogenases and NAD- and NADP-diaphorases were noted.
(6) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(7) Results indicated a .85 probability that Directive Guidance would be followed by Cooperation; a .67 probability that Permissiveness would lead to Noncooperation; and a .97 likelihood that Coerciveness would lead to either Noncooperation or Resistance.
(8) Multiple overlapping thin 3D slab acquisition is presented as a magnitude contrast (time of flight) technique which combines advantages from multiple thin slice 2D and direct 3D volume acquisitions to obtain high-resolution cross-sectional images of vessel detail.
(9) In addition to oncogenes, the transferred DNA contains genes that direct the synthesis and exudation of opines, which are used as nutrients by the bacteria.
(10) A total of 104 evaluable patients 20-90 years old treated by direct vision internal urethrotomy a.m. Sachse for urethral strictures reported retrospectively via a questionnaire their sexual potency before and after internal urethrotomy.
(11) However, direct measurements of mediator release should be carried out to reach a firm conclusion.
(12) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(13) These data indicate that RNA faithfully transfers "suppressive" as well as "positive" types of immune responses that have been reported previously for lymphocytes obtained directly from tumour-bearing and tumour-immune animals.
(14) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(15) The pancreatic changes are unlikely to be an artefact, but rather a direct toxic effect of the alcohol as confirmed by the biochemical changes.
(16) Errors in the initial direction of response were fewer in binocular viewing in comparison with monocular viewing.
(17) In the second approach, attachment sites of DTPA groups were directed away from the active region of the molecule by having fragment E1,2 bound in complex, with its active sites protected during the derivatization.
(18) The stages of mourning involve cognitive learning of the reality of the loss; behaviours associated with mourning, such as searching, embody unlearning by extinction; finally, physiological concomitants of grief may influence unlearning by direct effects on neurotransmitters or neurohormones, such as cortisol, ACTH, or norepinephrine.
(19) Completeness of isolation of the coronary and systemic circulations was shown by the marked difference in appearance times between the reflex hypotensive responses from catecholamine injections into the isolated coronary circulation and the direct hypertensive response from a similar injection when the circulations were connected as well as by the marked difference between the pressure pulses recorded simultaneously on both sides of the aortic balloon separating the two circulations.4.
(20) The direct monocyte source is not sufficient to insure the stability of this population.