(n.) A double sulphate formed of aluminium and some other element (esp. an alkali metal) or of aluminium. It has twenty-four molecules of water of crystallization.
(v. t.) To steep in, or otherwise impregnate with, a solution of alum; to treat with alum.
Example Sentences:
(1) Although alum adsorbed allergen could induce IgE synthesis in mice primed with liposome entrapped allergen the increase in serum specific IgE levels was lower than the animals primed and challenged with alum adsorbed allergen.
(2) Effective adjuvanticity as measured by the titre of the anti-peptide or anti-protein response in mice varied in the order: Algammulin, Montanide ISA 50 greater than or equal to Freund's adjuvant, Montanide ISA 708, 721, 70 much greater than alum, Squalene Arlacel greater than SAF-1.
(3) IgE levels in nude mice were estimated by the one-step single radial radiodiffusion method antisera prepared by immunization of guinea pigs with an IgE-rich fraction obtained from sera of normal mice infected with Nippostrongylus brasiliensis and immunized with DNP-ovalbumin in alum gel.
(4) Over 90% of the anti-OVA antibodies were of the IgGl isotype with both adjuvants; OVA in alum induced slightly more IgGl anti-OVA antibodies than cFA.
(5) Sections are brought to water, stained in Delafield's alum hematoxylin for 10 minutes, washed in tap water for 10 minutes, counterstained in 1% Procion brillant orange M-GS for 15 minutes and washed in distilled water for 10 minutes.
(6) The antibody responses of animals immunised with keyhole limpet hemocyanin (KLH) in Freund's Incomplete Adjuvant (FIA), diethylaminoethyl dextran (DEAE-dextran) and aluminium hydroxide (alum) were compared with the response to antigen administered in the absence of adjuvants.
(7) Wash thoroughly in water and place in 4% iron alum solution for two hours.
(8) The stability of ragweed extracts as measured by Antigen E content is markedly enhanced with little loss after 15 month storage at 4 degrees C, when the extract is prepared as an alum precipitated suspension.
(9) The choice of the carrier seemed to play an important role for both the level and maintenance of the secondary IgG response, attained as a consequence of a booster immunization with TT-alum.
(10) Six commercially available clostridial vaccines comprising one oil-emulsion, two alum-precipitated and three aluminum hydroxide adjuvanted preparations, each containing between two and seven antigenic components, were administered to groups of 10 rabbits and eight sheep in accordance with manufacturers' recommendations.
(11) So those undesirable gastric mucosa side effects that can be observed or presumed by the intake of NaF and CaF2 + alum are presumably neglibile.
(12) We reported previously that CBA mice pretreated with dinitrophenyl-Bordetella pertussis (DNP-BP) conjugates exhibited sharply decreased anti-DNP IgE, and increased IgG2a antibodies following immunization with DNP-ovalbumin (DNP-OA) in alum.
(13) An experimental review of the Feulgen and gallocyanine-chrome-alum stains for quantitative cytophotometry of DNA in tissue sections yielded information on the preparation and staining of tissue for quantitative absorbance microspectrophotometry.
(14) Alum, due to its safety and efficacy remains the drug of first choice for persistent vesical hematuria.
(15) Antibodies to the preparation were induced in rabbits by using alum as an adjuvant.
(16) Prior inoculation of mice with alum-adsorbed anti-idiotype potentiated the immune response to a subsequent inoculation with either native HBsAg particles or with a synthetic HBsAg peptide.
(17) Genetically modified M (pre-S2+S; P31) protein (M-P31c) particles were formulated into a vaccine (TGP-943) through adsorption on to an alum adjuvant.
(18) Sequential treatment with 5 X Denhardt's solution followed by gelatin-chrome alum resulted in enhanced specificity of labelling and excellent chromosome morphology, as well as reduced levels of background.
(19) Despite positive staining reactions with the presumptive neurosecretory stains, paraldehyde-fuchsin and chrome-alum-hematoxylin, ultrastructurally these glands exhibit many non-neural characteristics.
(20) Primary immunization with alum prepared using AlK(SO4)2 and adjuvant enhanced IgE production in the guinea pig.
Sulphate
Definition:
(n.) A salt of sulphuric acid.
Example Sentences:
(1) Sixteen smooth Brucella strains were lysed and digested by proteinase K, and the LPS fractions analysed by sodium dodecyl sulphate polyacrylamide gel electrophoresis.
(2) The decomposition of nafcillin and penicillin G solutions was hastened significantly by magnesium sulphate due to effect on the pH values of the solutions.
(3) The K5 polysaccharide was N-deacetylated (by hydrazinolysis) and N-sulphated, and was then incubated with detergent-solubilized enzymes from a heparin-producing mouse mastocytoma, in the presence of adenosine 3'-phosphate 5'-phospho[35S] sulphate ([35S]PAPS).
(4) Plasma noradrenaline levels were depressed by 50% when demedullated fetuses were also subject to peripheral sympathectomy by guanethidine sulphate treatment.
(5) Chemically isolated separate preparations of the non-aggregating protein-chondroitin-keratin sulphate (PCKS) fraction from the hyaline cartilage and hyaluronic acid (HUA) of the vitreous body and of the umbilicus were investigated by electron microscopy.
(6) Granules in a few cells also contained sulphated mucin.
(7) Deficiency of glucosamine-6-sulphatase activity leads to the lysosomal storage of the glycosaminoglycan, heparan sulphate and the monosaccharide sulphate N-acetylglucosamine 6-sulphate and the autosomal recessive genetic disorder mucopolysaccharidosis type IIID.
(8) PT painting resulted in rather higher sensitivity with Triton X-100 than with sodium lauryl sulphate.
(9) For binding measurements self-diffusion equilibrium dialysis with dodecyl [35S] sulphate was used.
(10) We tested for the distribution of basement membrane (BM) components collagen IV, laminin, heparan sulphate proteoglycan, fibronectin, for S100 protein and for the presence of interstitial collagens III and V. Laminin was generally noted in association with Schwann cells, but collagen IV occurred with perineural cells.
(11) Ammonium sulphate fractionation followed by immunoaffinity chromatography on a three column system using Protein A-Sepharose coupled D5, produced purified p29.
(12) An enzyme (EC 2.8.2.1) that catalyses the transfer of sulphate from adenosine 3'-phosphate 5'-sulphatophosphate to phenols was purified approx.
(13) Platelet factor 4 was compared with protamine sulphate, which has similar biological properties, by electrophoresis at pH 2.2, in which both migrated as single bands but with differing mobility, and by amino acid analysis which showed a more normal distribution of residues than occurred in protamine sulphate.
(14) (a) Ammonium sulphate precipitation and gel filtration on Sepharose 4B.
(15) This inhibition was partially reversed on addition of the translocated substrates sulphate or selenate to the external medium: selenite which is not translocated does not protect against DIDS inhibition.
(16) Protamine sulphate in vitro antagonized anticoagulant properties but did not protect mice from toxic envenomation; because venom was also neurotoxic and showed a curare like effect at the neuromuscular junction.
(17) Degradation products of dermatan sulphate were not detected by either gel filtration or affinity chromatography on Polybrene-Sepharose at any time in either plasma or urine, indicating that administered dermatan sulphate is not catabolised by man.
(18) Internal alkalinization could also be induced by oleate upon the addition of potassium sulphate.
(19) Addition of rising concentrations of zinc sulphate to rat PRP produced inhibition of ADP-induced platelet aggregation.
(20) Both surfactants were extensively degraded in vivo to yield a common metabolite, butyric acid 4-[35S]sulphate, the major urinary radioactive component.