(1) Among the patients suffering from acute myeloid leukaemia (AMeL), positive c-fms cells were found in 55% cases.
(2) A genetic disorder of enamel development (amelogenesis imperfecta) has been linked to the amelogenin gene AMEL(2-3), and loci regulating enamel thickness and tooth size have been mapped to the human sex chromosomes (4).
(3) The position of the amelogenin locus (Amel) relative to the loci for alpha-galactosidase (Ags), proteolipoprotein (Plp), and the random genomic probe DXWas31 has been determined.
(4) The mouse genome has been shown to contain only one copy of the amelogenin (AMEL) gene which is not amplified or rearranged during ameloblast determination.
(5) An assignment of human AMEL gene to the X chromosome p22 region together with a recent assignment of the X-linked AI disease locus to the Xp22.2 region support the association of the AMEL-X gene with AI.
(6) Afterwards, in 2 subsequent pregnancies, 2 amelic fetuses were diagnosed by transabdominal ultrasonography in the 18th and 12th week of gestation.
(7) In contrast, the human genome contains two copies of the AMEL gene, one residing on the X chromosome and one upon the Y chromosome.
(8) This also leads us to propose that a mutated AMEL-X gene produces altered amelogenin polypeptide, which is defective in its ability to participate in mineralization of enamel matrix, thus giving rise to the X-linked phenotypes of AI.
(9) Amel is established as: (1) the most distal locus in the genetic map of the mouse X chromosome, (2) lying proximal to the X:Y pairing region, and (3) being restricted to the mouse X chromosome.
(10) A term amelic female infant was born to an apparently nonconsanguineous Arab Moslem couple.
(11) Poland’s Adam Kszczot took silver while the Bosnian athlete Amel Tuka was third.
(12) The segregation of species-type alleles of amelogenin (Amelb and Amels), a distal X chromosome locus adjacent to the X-Y pairing region, was followed in backcross males that were analyzed for X-Y dissociation and sterility (we have used Amel as the designation for the mouse amelogenin locus; the current designation for this locus is Amg).
(13) We have determined that human AMEL sequences are located on the distal short arm of the X chromosome in the p22.1----p22.3 region and near the centromere on the Y chromosome, possibly at the proximal long arm (Yq11) region.
(14) Unlike the locus in humans, the mouse AMEL locus appears to be assigned solely to the X chromosome.
(15) Southern blot analysis of genomic DNA from the mouse using this cDNA as a probe indicates that there is only one mouse amelogenin (Amel) gene.
(16) Finally, together with the data on other X and Y chromosome sequences, these data for AMEL mapping support the notion of a pericentric inversion occurring in the human Y chromosome during primate evolution.
(17) The complementary DNA for mouse amelogenin gene (AMEL) has been cloned, characterized, and used as a probe to establish the chromosomal locations of AMEL for mouse and man.
(18) The human AMEL gene sequences have been located to the distal short arm p22.1----p22.3 region of the X chromosome, and the pericentromeric region of the Y chromosome.
(19) We have determined the chromosomal locations for the human and mouse amelogenin (AMEL) loci using Southern blot analyses of DNA from human, mouse, or somatic cell hybrids by hybridization to a characterized mouse amelogenin cDNA.
(20) Ehrlich ascites tumour, spleen (mouse), lymphatic leukemia L1210 and melanoma AMel 3 (hamster) are not influenced under identical experimental conditions.
Amen
Definition:
(v. t.) To say Amen to; to sanction fully.
(interj., adv., & n.) An expression used at the end of prayers, and meaning, So be it. At the end of a creed, it is a solemn asseveration of belief. When it introduces a declaration, it is equivalent to truly, verily.
Example Sentences:
(1) The methodology, in algorithm form, should assist health planners in developing objectives and actions related to the occurrence of selected health status indicators and should be amenable to health care interventions.
(2) Most of these other factors are under the control of the investigator, and thus are amenable to improvement.
(3) Studies of E1A support the notion that small DNA tumour viruses target cellular pathways at key points that are amenable to regulation.
(4) The other three were of the thoracoomphalopagus type with major cardiac and other abnormalities, they were not amenable to surgery and did not survive.
(5) These long-term effects of therapy have important implications, as some are amenable to treatment and others may be prevented by the careful monitoring of drug and radiation administration.
(6) The aims of this study were to examine mortality in one village in Israel and to determine which deaths could have been prevented by identifying those which were associated with avoidable factors or were caused by conditions which would have been amenable to preventive measures.
(7) There was no mortality and no allograft loss from these complications, which tend to occur late and be amenable to prompt repair.
(8) Consideration was given to length and sequence composition in an effort to maximize triple-strand formation under conditions amenable to the formation of the UL9-DNA complex.
(9) These results indicated that standardized fitness tests can predict performance on some CTT tasks and that test predictors were amenable to exercise training.
(10) From the original concept of encapsulating hemoglobin in an inert shell, LEH has evolved into a fluid proven to carry oxygen, capable of surviving for reasonable periods in the circulation, and amenable to large-scale production.
(11) In symptomatic cases, extraluminal diverticula are amenable to surgery, whereas intraluminal diverticula may be either surgically or endoscopically resected.
(12) The aspect of permanence may involve periods of many years, and is not amenable to standardization; meaningful limitation is subject to the individual needs, based on critical scientific follow-along of rehabilitation.
(13) We conclude that the quantitative aspects of bacterial anion exchange are amenable to study in an artificial system, and that the use of osmolytes as general stabilants can be a valuable adjunct to current techniques for reconstitution of integral membrane transport proteins.
(14) The results suggested that the modified tyrosine residues responsible for the activation were not involved in the active site of pseudocholinesterase or aryl acylamidase and that they were more amenable for modification in comparison to the residues responsible for inactivation.
(15) Cor triatriatum dexter is rare and is infrequently diagnosed before postmortem study; however, once the diagnosis is extablished, the condition is amenable to a relatively simple surgical correction.
(16) Local ownership and opportunities for action Organisations that use data to effectively support improvement know that you often need to break it down to the local level to understand variation and make it amenable to action for staff.
(17) These preliminary findings are important because they suggest that the dysfunctional sleep patterns of girls with the Rett syndrome may be amenable to behavioral treatments.
(18) We also discuss the amenability of surgical correction as well as the mechanisms of the intravenous growth of this type of tumor.
(19) They also suggest that the B6 background expresses an Igh allotype particularly amenable to autoantibody production, in spite of the relatively mild SLE-like syndrome in this strain.
(20) While many forms of male factor infertility are amenable to treatment, for some patients there is no corrective therapy available.