(1) Among the patients suffering from acute myeloid leukaemia (AMeL), positive c-fms cells were found in 55% cases.
(2) A genetic disorder of enamel development (amelogenesis imperfecta) has been linked to the amelogenin gene AMEL(2-3), and loci regulating enamel thickness and tooth size have been mapped to the human sex chromosomes (4).
(3) The position of the amelogenin locus (Amel) relative to the loci for alpha-galactosidase (Ags), proteolipoprotein (Plp), and the random genomic probe DXWas31 has been determined.
(4) The mouse genome has been shown to contain only one copy of the amelogenin (AMEL) gene which is not amplified or rearranged during ameloblast determination.
(5) An assignment of human AMEL gene to the X chromosome p22 region together with a recent assignment of the X-linked AI disease locus to the Xp22.2 region support the association of the AMEL-X gene with AI.
(6) Afterwards, in 2 subsequent pregnancies, 2 amelic fetuses were diagnosed by transabdominal ultrasonography in the 18th and 12th week of gestation.
(7) In contrast, the human genome contains two copies of the AMEL gene, one residing on the X chromosome and one upon the Y chromosome.
(8) This also leads us to propose that a mutated AMEL-X gene produces altered amelogenin polypeptide, which is defective in its ability to participate in mineralization of enamel matrix, thus giving rise to the X-linked phenotypes of AI.
(9) Amel is established as: (1) the most distal locus in the genetic map of the mouse X chromosome, (2) lying proximal to the X:Y pairing region, and (3) being restricted to the mouse X chromosome.
(10) A term amelic female infant was born to an apparently nonconsanguineous Arab Moslem couple.
(11) Poland’s Adam Kszczot took silver while the Bosnian athlete Amel Tuka was third.
(12) The segregation of species-type alleles of amelogenin (Amelb and Amels), a distal X chromosome locus adjacent to the X-Y pairing region, was followed in backcross males that were analyzed for X-Y dissociation and sterility (we have used Amel as the designation for the mouse amelogenin locus; the current designation for this locus is Amg).
(13) We have determined that human AMEL sequences are located on the distal short arm of the X chromosome in the p22.1----p22.3 region and near the centromere on the Y chromosome, possibly at the proximal long arm (Yq11) region.
(14) Unlike the locus in humans, the mouse AMEL locus appears to be assigned solely to the X chromosome.
(15) Southern blot analysis of genomic DNA from the mouse using this cDNA as a probe indicates that there is only one mouse amelogenin (Amel) gene.
(16) Finally, together with the data on other X and Y chromosome sequences, these data for AMEL mapping support the notion of a pericentric inversion occurring in the human Y chromosome during primate evolution.
(17) The complementary DNA for mouse amelogenin gene (AMEL) has been cloned, characterized, and used as a probe to establish the chromosomal locations of AMEL for mouse and man.
(18) The human AMEL gene sequences have been located to the distal short arm p22.1----p22.3 region of the X chromosome, and the pericentromeric region of the Y chromosome.
(19) We have determined the chromosomal locations for the human and mouse amelogenin (AMEL) loci using Southern blot analyses of DNA from human, mouse, or somatic cell hybrids by hybridization to a characterized mouse amelogenin cDNA.
(20) Ehrlich ascites tumour, spleen (mouse), lymphatic leukemia L1210 and melanoma AMel 3 (hamster) are not influenced under identical experimental conditions.
Avel
Definition:
(v. t.) To pull away.
Example Sentences:
(1) I felt the key was to use stretched vowels and to find an equivalent echo between "tout" and "tournaient": "They were reeling round: all reeled round and about them …" Historical details took hours of research: for a debauched night, Emma sports a "lampion" on one ear: not the unlikely "paper lantern" (Wall), nor a "cocked hat" ( Eleanor Marx Aveling , Russell and Davis), but a suitably Gypsy-like "lantern earring" – fashionable at the time.