(1) Among the patients suffering from acute myeloid leukaemia (AMeL), positive c-fms cells were found in 55% cases.
(2) A genetic disorder of enamel development (amelogenesis imperfecta) has been linked to the amelogenin gene AMEL(2-3), and loci regulating enamel thickness and tooth size have been mapped to the human sex chromosomes (4).
(3) The position of the amelogenin locus (Amel) relative to the loci for alpha-galactosidase (Ags), proteolipoprotein (Plp), and the random genomic probe DXWas31 has been determined.
(4) The mouse genome has been shown to contain only one copy of the amelogenin (AMEL) gene which is not amplified or rearranged during ameloblast determination.
(5) An assignment of human AMEL gene to the X chromosome p22 region together with a recent assignment of the X-linked AI disease locus to the Xp22.2 region support the association of the AMEL-X gene with AI.
(6) Afterwards, in 2 subsequent pregnancies, 2 amelic fetuses were diagnosed by transabdominal ultrasonography in the 18th and 12th week of gestation.
(7) In contrast, the human genome contains two copies of the AMEL gene, one residing on the X chromosome and one upon the Y chromosome.
(8) This also leads us to propose that a mutated AMEL-X gene produces altered amelogenin polypeptide, which is defective in its ability to participate in mineralization of enamel matrix, thus giving rise to the X-linked phenotypes of AI.
(9) Amel is established as: (1) the most distal locus in the genetic map of the mouse X chromosome, (2) lying proximal to the X:Y pairing region, and (3) being restricted to the mouse X chromosome.
(10) A term amelic female infant was born to an apparently nonconsanguineous Arab Moslem couple.
(11) Poland’s Adam Kszczot took silver while the Bosnian athlete Amel Tuka was third.
(12) The segregation of species-type alleles of amelogenin (Amelb and Amels), a distal X chromosome locus adjacent to the X-Y pairing region, was followed in backcross males that were analyzed for X-Y dissociation and sterility (we have used Amel as the designation for the mouse amelogenin locus; the current designation for this locus is Amg).
(13) We have determined that human AMEL sequences are located on the distal short arm of the X chromosome in the p22.1----p22.3 region and near the centromere on the Y chromosome, possibly at the proximal long arm (Yq11) region.
(14) Unlike the locus in humans, the mouse AMEL locus appears to be assigned solely to the X chromosome.
(15) Southern blot analysis of genomic DNA from the mouse using this cDNA as a probe indicates that there is only one mouse amelogenin (Amel) gene.
(16) Finally, together with the data on other X and Y chromosome sequences, these data for AMEL mapping support the notion of a pericentric inversion occurring in the human Y chromosome during primate evolution.
(17) The complementary DNA for mouse amelogenin gene (AMEL) has been cloned, characterized, and used as a probe to establish the chromosomal locations of AMEL for mouse and man.
(18) The human AMEL gene sequences have been located to the distal short arm p22.1----p22.3 region of the X chromosome, and the pericentromeric region of the Y chromosome.
(19) We have determined the chromosomal locations for the human and mouse amelogenin (AMEL) loci using Southern blot analyses of DNA from human, mouse, or somatic cell hybrids by hybridization to a characterized mouse amelogenin cDNA.
(20) Ehrlich ascites tumour, spleen (mouse), lymphatic leukemia L1210 and melanoma AMel 3 (hamster) are not influenced under identical experimental conditions.
Enamel
Definition:
(v. t.) A variety of glass, used in ornament, to cover a surface, as of metal or pottery, and admitting of after decoration in color, or used itself for inlaying or application in varied colors.
(v. t.) A glassy, opaque bead obtained by the blowpipe.
(v. t.) That which is enameled; also, any smooth, glossy surface, resembling enamel, especially if variegated.
(v. t.) The intensely hard calcified tissue entering into the composition of teeth. It merely covers the exposed parts of the teeth of man, but in many animals is intermixed in various ways with the dentine and cement.
(v. t.) To lay enamel upon; to decorate with enamel whether inlaid or painted.
(v. t.) To variegate with colors as if with enamel.
(v. t.) To form a glossy surface like enamel upon; as, to enamel card paper; to enamel leather or cloth.
(v. t.) To disguise with cosmetics, as a woman's complexion.
(v. i.) To practice the art of enameling.
(a.) Relating to the art of enameling; as, enamel painting.
Example Sentences:
(1) A total of 555 caries lesions were registered on proximal surfaces, 49.1% being primary lesions in the enamel, 21.4% primary lesions into the dentin and 29.5% secondary lesions.
(2) These cells contained organelles characteristic of the maturation stage ameloblast and often extended to the enamel surface, suggesting a possible origin from the ameloblast layer.
(3) It was found that there is a significant difference in bond strengths between enamel and stainless steel with strength to enamel the greater.
(4) Enamel was exclusively present opposite well developed dentine.
(5) Data is available to support the early influences of enamel organ epithelium upon a responding mesenchyme in the determination of dental morphogenetic fields (Dryburg, 1967; Miller, 1969).
(6) To determine the influence of cetylpyridinium chloride (CPC) adsorption on the wettability and elemental surface composition of human enamel, with and without adsorbed salivary constituents, surface-free energies and elemental compositions were determined.
(7) The 12-fluted bur caused no clinically identifiable marks on the enamel surface.
(8) Unaltered surface enamel of extracted human teeth was subjected to tests of resistance to dissolution in 10 mM acetic acid at pH 4.0 and 10 mM EDTA at pH 7.4 in a miniature continuous flow system.
(9) Secondary structural features of bovine amelogenin, a hydrophobic protein of developing enamel implicated in ename mineralization, are derived using 2D NMR spectroscopy in solution and molecular mechanics-dynamics studies.
(10) Several functional properties of MG1, MG2, and PRG have been examined, including their presence in two-hour in vivo enamel pellicle, binding to synthetic hydroxyapatite, lubricating properties, and interactions with oral streptococci.
(11) A thorough dental prophylaxis before acid-etching of enamel is often recommended.
(12) Changes of mineral content in the approximal enamel of the teeth were determined in situ with quantitative bite-wing radiography.
(13) On the fourth day of culture, the pre-ameloblasts achieved terminal differentiation into secretory ameloblasts, and enamel and dentin had already been deposited.
(14) This resulted in greater uniformity of abrasion over the enamel surface within the biopsy window area and better operator handling characteristics.
(15) The 33,000 molecular weight protease was also active against enamel proteins.
(16) Significantly more remineralization was observed in enamel samples treated with the toothpaste containing 2,500 ppm F compared to that containing 1500 ppm F. This result is consistent with the outcome of a recent caries clinical trial testing the same toothpastes and finding enhanced anticaries efficacy from the higher fluoride level.
(17) This demineralization was similar to enamel acid etched with 50% phosphoric acid for 2 mn.
(18) The data show that the structure of inner and outer enamel layers differ between these two carnivore species and that the enamel structure of the cat was most similar to that described in humans.
(19) Maturing enamel overlaid by either ruffle-ended or smooth-ended maturation ameloblasts showed similar Ca and P concentrations.
(20) Although the crystallite widths were similar in both AI and normal enamel, the AI teeth showed areas where the crystallite order and continuity appeared disrupted.