(n.) A compound formed by the union of amidogen with an acid element or radical. It may also be regarded as ammonia in which one or more hydrogen atoms have been replaced by an acid atom or radical.
Example Sentences:
(1) Since the start of this week, markets have been more cautious, with bond yields in Spain reaching their highest levels in four months on Tuesday amid concern about the scale of the austerity measures being imposed by the government and fears that the country might need a bailout.
(2) Businesses fleeing Brexit will head to New York not EU, warns LSE chief Read more Amid attempts by Frankfurt, Paris and Dublin to catch possible fallout from London, Sir Jon Cunliffe said it was highly unlikely that any EU centre could replicate the services offered by the UK’s financial services industry.
(3) Amid the passionate discussion at the NDA meeting, the two women began to develop a plan.
(4) Amid the acrimony of the failed debate on the Malaysia Agreement, something was missed or forgotten: many in the left had changed their mind.
(5) The presence of a previously unreported dipeptide transport mechanism within blood leukocytes and the selective enrichment of the granule enzyme, DPPI, within cytotoxic effector cells of lymphoid or myeloid lineage appear to afford a unique mechanism for the targeting of immunotherapeutic reagents composed of simple dipeptide esters or amides.
(6) Seconds later the camera turns away as what sounds like at least 15 gunshots are fired amid bystanders’ screams.
(7) Amid all of the worry about her health, the difficult decisions around the surgery, and how to explain everything to the children, the practicalities of postponing the holiday was a relatively minor consideration.
(8) The alignment of Clinton’s Iowa team, all but guaranteeing a declaration of her official campaign before the end of next month, was coming into view amid reports that she was due to address by the end of the week controversy over her use of a private email account as secretary of state.
(9) The aza analogue (RS)-3-hydroxy-2,5-pyrrolidinedione-3-acetic acid (6) of the five-membered citric anhydride (2) was prepared in the sequence citric acid----2-phenyl-1,3-dioxolan-4-one-5,5-diacetic acid (1)----citric acid beta-amide (3)----6 and used to resolve ambiguities in the mechanism of the citrate synthase reaction.
(10) These results, in addition to binding studies with the active site titrant N2-(5-dimethylaminonaphthalene-1-sulfonyl)arginine N-(3-ethyl-1,5-pentanediyl)amide, indicate that binding interactions at the catalytic site of Thrombin Quick I are unaltered.
(11) Displacement of the active ester in the gel thus formed by various ligands containing aliphatic amino groups resulted in the formation of stable amid bonds between the ligands and the polyacrylamide gel.
(12) Arsenal’s 10 men fall at the first hurdle against Dinamo Zagreb Read more This win, even against such feeble opponents, was celebrated, with the locals chorusing their manager’s name amid a wave of relief given so much of the team’s domestic campaign to date has been dismal.
(13) Free radicals formed by the reactions of OH radicals with amides and their N-methylated derivatives in aqueous solutions have been studied.
(14) In EastEnders , the mystery surrounding the identity of Kat's secret squeeze continues amid the grinding of narrative levers and the death rattle of overflogged script-horses.
(15) Guanine nucleotides (GTP-gamma-S, GDP-beta-S) decreased the binding of 125I-labelled GLP-1(7-36)amide to rat lung membranes as was found for GLP-1(7-36)amide receptors in RINm5F cells which were also shown to be coupled to the adenylate cyclase system.
(16) The ester group in the N-acyloxymethyl derivatives was readily hydrolyzed by plasma enzymes to yield the N-hydroxymethyl amide, which subsequently decomposed to the parent amide.
(17) Soon after the takeover, PFD creative director Sue Douglas, the former Sunday Express editor, left amid reports that the company wasn't big enough for "two alpha females in Chanel".
(18) Pancreastatin is a 49 amino acid peptide with a C-terminal glycine amide originally isolated from porcine pancreas.
(19) The announcement comes amid mounting frustration in the international community over Israel’s continued settlement activity, regarded by many countries as illegal.
(20) Losing Murphy is a blow to the Oscars which has struggled to liven up its image amid a general decline in its TV ratings over the last couple of decades and a rush of awards shows that appeal to younger crowds, such as the MTV Movie Awards.
Diamide
Definition:
(n.) Any compound containing two amido groups united with one or more acid or negative radicals, -- as distinguished from a diamine. Cf. Amido acid, under Amido, and Acid amide, under Amide.
Example Sentences:
(1) In intact cell preparations, diamide produced a slow tonic contraction, consistent with myofibril activation.
(2) Moreover, the accelerated rate of methylglucose uptake produced by diamide treatment is not inhibited by cytochalasin B, an agent that blocks basal and insulin-stimulated methylglucose transport.
(3) The thiol oxidizing agent diamide inhibited both vaso- and bronchoconstriction induced by H2O2, AA, or U-44069.
(4) Liver was the most responsive to these agents in that all 11 chemicals increased MT concentrations in liver, with diethyl maleate, paraquat, and diamide producing 20- to 30-fold increases.
(5) This study deals with the effects of the SH oxidizing agent diamide (diazene dicarboxylic acid bis-(N,N-dimethyl-amide)) on the water-soluble proteins from rabbit lenses.
(6) Following the complete GSH oxidation diamide impaired the turnover of PIP and PA dramatically.
(7) Furthermore, we observed cross-resistance and self-tolerance with three seemingly unrelated stimuli (diamide, heat, and sodium arsenite).
(8) The diamide inhibition was reversible, and H2O2-induced vaso- and bronchoconstriction was almost maximal after 10 min of perfusion with buffer.
(9) After mild treatment of spectrin with 2.5 microM diamide, with formation of an average of only one disulfide bond, we observed a 50% reduction in the ability of protein 4.1 to amplify spectrin-actin binding.
(10) No additive effect was observed when the cells were simultaneously treated with diamide and verapamil.
(11) N-ethylmalemide and diamide irreversibly inhibited endocytosis of all ligands tested, whereas low pH in the cytosol strongly inhibited endocytosis of transferrin and EGF.
(12) A diamide concentration dependent IgG loading of erythrocytes was observed.
(13) These effects increase with diamide concentrations up to 2-2.5 mM and are persistent after removal of the reagent.
(14) Diamide oxidized intracellular glutathione in these cells and produced extensive protein S-thiolation.
(15) In isolated rat pancreatic islets, the effect of diamide and N-ethylmaleimide (NEM) on forskolin- as well as on glucagon-induced elevation of cAMP was studied.
(16) Nutritional supplementation with Mn(II) favored occupancy of the MnSOD active site with manganese and allowed anaerobic accumulation of Mn2-MnSOD in the absence of diamide.
(17) Although NEM substantially potentiated the flow-induced release of prostacyclin (PGI2), probably due to a blockade of the reacylation of arachidonic acid, it inhibited the stimulated release of PGI2, whereas diamide did not significantly affect either release.
(18) A similar increase in the ability of diamide to cause anaerobic biosynthesis of active MnSOD was seen when the production of the MnSOD polypeptide was increased by isopropyl-beta-D-thiogalactopyranoside, in a strain bearing the MnSOD gene under the control of the tac promoter.
(19) Diamide caused anaerobic induction of active MnSOD and this effect was also observed in a glutathione-negative strain.
(20) Flow cytometric analysis of nitrofurantoin-treated spermatozoa showed that nitrofurantoin maintained the sperm disulfides formed by diamide and prevented the reduction of sperm disulfides back to sulfhydryls.