(n.) The act of amplifying or enlarging in dimensions; enlargement; extension.
(n.) The enlarging of a simple statement by particularity of description, the use of epithets, etc., for rhetorical effect; diffuse narrative or description, or a dilating upon all the particulars of a subject.
(n.) The matter by which a statement is amplified; as, the subject was presented without amplifications.
Example Sentences:
(1) A full-length cDNA encoding porcine heart aconitase was derived from lambda gt10 recombinant clones and by amplification of the 5' end of the mRNA.
(2) Ten out of 12 (83%) tumours which had c-erbB-2 and c-erbA co-amplification had metastasised to axillary lymph nodes (P less than 0.006).
(3) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(4) Of great influence on the results of measurements are preparation and registration (warm-up-time, amplification, closeness of pressure-system, unhurt catheters), factors relating to equipment and methods (air-bubbles in pressure-system, damping by filters, continuous infusion of the micro-catheter, level of zero-pressure), factors which occur during intravital measurement (pressure-drop along the arteria pulmonalis, influence of normal breathing, great intrapleural pressure changes, pressure damping in the catheter by thrombosis and external disturbances) and last not least positive and negative acceleration forces, which influence the diastolic and systolic pulmonary artery pressure.
(5) Reverse transcription of retina mRNA followed by DNA amplification using D4-specific nucleotides demonstrates the presence of D4 mRNA in retina.
(6) Studies on asparagine synthetase indicate that resistance to albizziin may be due to altered regulation of asparagine synthetase, structural mutations of the enzyme, and gene amplification.
(7) The results of the oestrogen amplification test in eleven of the non-hyperprolactinaemic anovular patients were compared with the ovulatory response to 100 mg clomiphene given for 5 days.
(8) The 500-bp element arose by duplication of one half of a 180-bp ancestor and insertion of a foreign segment between the two duplicated parts followed by amplification.
(9) When PCR products in each of the 12 cats were subjected to a second amplification using the same primer pair (two-step amplification: double PCR), FIV proviral DNA was detected in all of the cats.
(10) We have investigated the presence of fragments of the HIV genome with a new nucleic acid amplification technique (PCR or polymerase chain reaction) in lymphocytes from 33 seronegative couples with anti-HIV antibodies, most of which were heroin addicts.
(11) Polymerase chain reaction (PCR) amplification of cDNA confirmed this reduced level of DAF mRNA.
(12) Programmed gene rearrangements are used in nature to to alter gene copy number (gene amplification and deletion), to create diversity by reassorting gene segments (as in the formation of mammalian immunoglobulin genes), or to control the expression of a set of genes that code for the same function (such as surface antigens).
(13) The sensitivity of a PCR system to amplify the long terminal repeat (LTR) sequence of HIV-1 was not affected by the irradiation procedure; however, the ultimate sensitivity of a PCR system for the amplification of an early gene promotor sequence of the CMV genome was reduced 1000-fold.
(14) In one patient with gastric carcinoma a c-Ha-ras-1 overexpression was detected due to its amplification both in tumour tissues and in regional metastasis.
(15) The ratio of products remains constant through the amplification and can be readily quantitated.
(16) Thus MTX combined with PALA selected cells with an 'amplificator' phenotype (an increased ability to amplify parts of the genome).
(17) Concomitant with gene amplification, an induction of 20-65-fold in the expression of NS1 and NS2 proteins was observed after temperature shift-down.
(18) "In-gel renaturation" analysis did not show any DNA amplification of high degree in AT22IJE-T. Cytogenetic analysis showed considerable chromosomal instability in the new cell line, and medium conditioned by these cells contained the clastogenic activity which is characteristic of the parental strain as well.
(19) All nine responders were negative for HBV DNA in serum by dot blot during or after treatment, but seven remained positive by polymerase chain amplification and Southern-blot hybridization.
(20) Amplification of endothelial biomass has been accomplished by using freshly isolated capillaries as explants for primary tissue culture.
Amplitude
Definition:
(n.) State of being ample; extent of surface or space; largeness of dimensions; size.
(n.) Largeness, in a figurative sense; breadth; abundance; fullness.
(n.) Of extent of capacity or intellectual powers.
(n.) Of extent of means or resources.
(n.) The arc of the horizon between the true east or west point and the center of the sun, or a star, at its rising or setting. At the rising, the amplitude is eastern or ortive: at the setting, it is western, occiduous, or occasive. It is also northern or southern, when north or south of the equator.
(n.) The arc of the horizon between the true east or west point and the foot of the vertical circle passing through any star or object.
(n.) The horizontal line which measures the distance to which a projectile is thrown; the range.
(n.) The extent of a movement measured from the starting point or position of equilibrium; -- applied especially to vibratory movements.
(n.) An angle upon which the value of some function depends; -- a term used more especially in connection with elliptic functions.
Example Sentences:
(1) After midazolam infusion, there was a 50% decrease in amplitude of P3 in response to target tones (P less than 0.006), whereas N3 latency increased by 40 ms (P less than 0.05).
(2) A significant correlation was found between the amplitude ratio of the R2 and the sensitivity ratio of the rapid off-response at short and long wavelengths.
(3) Intact rams exhibited GH secretory episodes of greater (P less than 0.01) amplitude than did castrated lambs.
(4) The maximum amplitude of the inward Na+ current, normalized by cell capacitance, is about sixfold larger, on the average, in LP lactotropes than in SP lactotropes.
(5) The examination of the standard waves' amplitude and latency of the brain stem auditory evoked response (BAEP) was performed in 20 guinea pigs (males and females, weighing 250 to 300 g).
(6) The amplitudes of the a-wave and the 01 decreased in dose-dependent manners, but their changes were less striking than those of the 01 latency.
(7) We have now started a prospective follow-up study in order to pursue the development of (a) p-ERG amplitudes and (b) funduscopic changes and visual acuity in these patients.
(8) Noradrenaline decreased the phasic contraction amplitude of the circular muscle and exerted a stimulant effect on the tone which suggested an existence of two alpha 1-adrenoceptor subtypes.
(9) elution patterns of the adducts formed by DBF metabolites with DNA and obtained in vivo at the optimal exposure time of 42-48 h were qualitatively very similar to the patterns obtained in vitro, but their amplitude was quantitatively reduced.
(10) In contrast, the average reduction in mean EEG amplitude with isoflurane was only 0.3% and there were neither periods of suppression nor any correlation between EEG amplitude and MAP.
(11) However, the effect of prior jaw motion and the effect of the recording site on the EMG amplitudes and on the vertical dimension of minimum EMG activity have not been documented.
(12) The ophthalmic headache's crisis is caused, in fact, by a spasm of convergence on an unknown exophory of which the amplitude of fusion is satisfying, and the presence of which can only be seen with test under screen.
(13) Moreover, the most recent combined application of the rat interstitial cell testosterone (RICT) bioassay and a novel multiple-parameter deonvolution model has allowed investigators to dissect plasma concentration profiles of bioactive LH into defined secretory bursts, which have numerically explicit amplitudes, locations in time, and durations, and are acted upon by determinable subject- and study-specific endogenous metabolic clearance rates.
(14) By this action, oxytocin is believed to increase the probability of successful regenerative spikes and thereby initiate electrical activity in quiescent preparations, increase the frequency of burst discharges, the number of spikes in each burst, and the amplitude of spikes in individual cells.
(15) Replication dependent on the SV40 origin and having the kinetics and approximate amplitude of an SV40 infection ensued.
(16) For the case of the fluctuating pressure, the strength of the artery becomes considerably lower than those under constant amplitude and two-step-multi-duplicated pulsatile pressure.
(17) Complex tones containing the first 20 harmonics of 50, 100, or 200 Hz, all at equal amplitude, were used.
(18) In the placebo group of 14 patients CNV-amplitudes even decreased after ten Infusions with multi-vitamins alone.
(19) ERGs of high amplitude and of normal wave form were recordable with prominent oscillatory potentials.
(20) increase in amplitude in both, hippocampus and neocortex was observed with MK 801 and ketamine and these agents also showed longer lasting influence.