(a.) Capable of rendering insensible; as, anaesthetic agents.
(a.) Characterized by, or connected with, insensibility; as, an anaesthetic effect or operation.
(n.) That which produces insensibility to pain, as chloroform, ether, etc.
Example Sentences:
(1) Typical kinetics of local anaesthetics are presented for various methods of regional anaesthesia informing the anaesthetist on corresponding plasma concentrations if the recommended maximum doses are exceeded and thus he gets useful information for his daily work.
(2) With attention to proper performance and patient selection, spinal and epidural anaesthesia are safe and efficacious options when choosing anaesthetic technique.
(3) The response to LBNP in the pentobarbitone-anaesthetized rat appeared not to be influenced by the autonomic nervous system.
(4) Indeed, several lines of evidence suggest that intravenous anaesthetics are thought to induce loss of consciousness by blocking the excitatory synaptic transmission.
(5) Gallbladder mucosal net fluid transport and motility were measured in vivo by a continuous perfusion technique in the anaesthetized cat.
(6) The effect of histamine on coronary blood flow (CBF) was studied in anaesthetized grayhounds.
(7) A method for continuous measurement of the anaesthetic Ethrane in blood and gas samples is described.
(8) The regional differences of myocardial oxygenation were studied in anaesthetized open-chest dogs by measuring the myocardial perfusion rate, the microvascular hematocrit, the PS-product of 51Cr-EDTA, and the microvascular blood volume across the left ventricular wall in the heart working in situ.
(9) An epidemiological survey carried out in 460 public and private institutions chosen at random country-wide in France made it possible to study injuries whose treatment had necessitated an anaesthetic.
(10) In order to investigate the ability of a computer-assisted continuous infusion (CACI) system to maintain constant plasma levels of sufentanil during cardiopulmonary bypass (CPB) using pharmacokinetic data derived from healthy surgical patients to determine the infusion rate, ten patients were anaesthetized with diazepam, enflurane and oxygen until ten minutes prior to the expected time of initiation of CPB.
(11) Molecular biology and electrophysiology have shown different mechanisms of action on this sodium channel, which depend on the chemical structure and electrostatic charge of the local anaesthetic molecule.
(12) Chloralose-urethane is considered a suitable anaesthetic in rats when studying the effects of noradrenaline and guanethidine.
(13) The increase probably reflects an inhibition of the re-uptake of released 3H-noradrenaline; in addition, phencyclidine appears to enhance the release of noradrenaline per pulse.--The actions of phencyclidine and ketamine on central noradrenergic neurones may contribute to the characteristic psychotropic side-effects of these general anaesthetics.
(14) In 12 anaesthetized mongrel dogs, a canine stroke model was produced by occluding the left internal carotid and middle cerebral arteries with aneurysm clips.
(15) The hepatic balance for valine, leucine and isoleucine has been measured in anaesthetized virgin controls and 9 and 12-day pregnant rats.
(16) With an ambulance service staffed by doctors from the anaesthetic and intensive care units of the central hospitals it is possible to provide prehospital treatment in 70% of all severe traffic injuries in the County of Ringkøbing.
(17) Moreover, anaesthetic wash-out in children differed from that in adults.
(18) Furthermore, an association of tiapride-corticoids was effective in treating post-anaesthetic spasm of the glottis.
(19) However EMLA is a useful anaesthetic for taking biopsies in this area and may be used as premedication for local infiltration.
(20) Seven or 14 days of treatment with the beta 2-adrenoceptor agonist clenbuterol, 0.3 mg kg-1, s.c., twice daily, increased the basal mean blood pressure in normotensive urethane-anaesthetized rats.
Narcotic
Definition:
(a.) Having the properties of a narcotic; operating as a narcotic.
(n.) A drug which, in medicinal doses, generally allays morbid susceptibility, relieves pain, and produces sleep; but which, in poisonous doses, produces stupor, coma, or convulsions, and, when given in sufficient quantity, causes death. The best examples are opium (with morphine), belladonna (with atropine), and conium.
Example Sentences:
(1) The clinical usefulness of neonatal narcotic abstinence scales is reviewed, with special reference to their application in treatment.
(2) Recent research conducted by independent investigators concerning the relationship between crime and narcotic (primarily heroin) addiction has revealed a remarkable degree of consistency of findings across studies.
(3) The interactions of 3 classical alpha-adrenergic antihypertensives of prevalently central type (St 155 or clonidine St 600; BR 750 or guanabenz) with the narcotic effects of pentobarbital have been investigated in the Mus musculus.
(4) We studied the arterial blood gas determinations done on the first hospital day in 14 narcotic addicts with bacterial endocarditis (group 1) and six addicts with other medical complications of narcotic addiction (group 2).
(5) The prostaglandins A1, E1, A2, E2 and F2a were comparatively studied for their antiarrhythmic action using the model of strophanthin arrhythmia of narcotized cats.
(6) Postoperative nausea and vomiting have been associated with the use of intravenous narcotics, and nitrous oxide may worsen the emetic effects of narcotics.
(7) Though intraspinal narcotic analgesia is associated with a number of side effects, with proper knowledge these adverse reactions are wither preventable or can be greatly reduced.
(8) In this open study we reviewed the circadian distribution of extra doses of narcotic analgesics in 61 bed-ridden patients with cancer pain.
(9) In narcotized cats different respiratory reactions in acute myocardial ischemia was estimated with complicated and non-complicated ventricular fibrillation.
(10) Infants prenatally exposed to narcotics become passively addicted in-utero and may undergo neonatal abstinence at birth.
(11) Convergent results from a multimethod assessment of the issue show that methadone maintenance has long-term and short-term suppressive effects on narcotics use and property crime.
(12) The pharmacokinetics of the narcotic analgesic dextromoramide was investigated by means of a specific GC-MS method in 9 patients who were given a single oral dose of the drug (7.5 mg) together with an anticholinergic before undergoing minor orthopedic surgery.
(13) Ethanol-withdrawn animals displayed an increased sensitivity to the narcotic action of toluene.
(14) Their addiction at the time of seeking treatment was well established: narcotic drugs comprised their main daily expenditure, they had numerous problems associated with narcotic use, and high doses of methadone were necessary for detoxification.
(15) These results provide further evidence that narcotic-induced respiratory depression and analgesia are mediated by different receptor interactions.
(16) Hypericum extract enhanced the exploratory activity of mice in a foreign environment, significantly prolonged the narcotic sleeping time dose-dependently, and within a narrow dose range exhibited reserpine antagonism.
(17) In summary, there are now available very potent narcotics, with small side effect liability.
(18) This paper analyses the influence of medical professional organization on the formation of attitudes and policies toward narcotics in England.
(19) Most involved children less than 3 (42%) yr or greater than 12 (33%) yr. Products most commonly ingested included tricyclic antidepressants (22%), benzodiazepines (15%), theophylline (10%), ethanol (10%), hallucinogens (8%), salicylates (8%), narcotics (8%), antihistamines (7%), and carbamazepine (5%).
(20) In this respect the narcotic antagonist effects resemble those produced by the antiserotonin compounds or opiate agonists.