(a.) Capable of rendering insensible; as, anaesthetic agents.
(a.) Characterized by, or connected with, insensibility; as, an anaesthetic effect or operation.
(n.) That which produces insensibility to pain, as chloroform, ether, etc.
Example Sentences:
(1) Typical kinetics of local anaesthetics are presented for various methods of regional anaesthesia informing the anaesthetist on corresponding plasma concentrations if the recommended maximum doses are exceeded and thus he gets useful information for his daily work.
(2) With attention to proper performance and patient selection, spinal and epidural anaesthesia are safe and efficacious options when choosing anaesthetic technique.
(3) The response to LBNP in the pentobarbitone-anaesthetized rat appeared not to be influenced by the autonomic nervous system.
(4) Indeed, several lines of evidence suggest that intravenous anaesthetics are thought to induce loss of consciousness by blocking the excitatory synaptic transmission.
(5) Gallbladder mucosal net fluid transport and motility were measured in vivo by a continuous perfusion technique in the anaesthetized cat.
(6) The effect of histamine on coronary blood flow (CBF) was studied in anaesthetized grayhounds.
(7) A method for continuous measurement of the anaesthetic Ethrane in blood and gas samples is described.
(8) The regional differences of myocardial oxygenation were studied in anaesthetized open-chest dogs by measuring the myocardial perfusion rate, the microvascular hematocrit, the PS-product of 51Cr-EDTA, and the microvascular blood volume across the left ventricular wall in the heart working in situ.
(9) An epidemiological survey carried out in 460 public and private institutions chosen at random country-wide in France made it possible to study injuries whose treatment had necessitated an anaesthetic.
(10) In order to investigate the ability of a computer-assisted continuous infusion (CACI) system to maintain constant plasma levels of sufentanil during cardiopulmonary bypass (CPB) using pharmacokinetic data derived from healthy surgical patients to determine the infusion rate, ten patients were anaesthetized with diazepam, enflurane and oxygen until ten minutes prior to the expected time of initiation of CPB.
(11) Molecular biology and electrophysiology have shown different mechanisms of action on this sodium channel, which depend on the chemical structure and electrostatic charge of the local anaesthetic molecule.
(12) Chloralose-urethane is considered a suitable anaesthetic in rats when studying the effects of noradrenaline and guanethidine.
(13) The increase probably reflects an inhibition of the re-uptake of released 3H-noradrenaline; in addition, phencyclidine appears to enhance the release of noradrenaline per pulse.--The actions of phencyclidine and ketamine on central noradrenergic neurones may contribute to the characteristic psychotropic side-effects of these general anaesthetics.
(14) In 12 anaesthetized mongrel dogs, a canine stroke model was produced by occluding the left internal carotid and middle cerebral arteries with aneurysm clips.
(15) The hepatic balance for valine, leucine and isoleucine has been measured in anaesthetized virgin controls and 9 and 12-day pregnant rats.
(16) With an ambulance service staffed by doctors from the anaesthetic and intensive care units of the central hospitals it is possible to provide prehospital treatment in 70% of all severe traffic injuries in the County of Ringkøbing.
(17) Moreover, anaesthetic wash-out in children differed from that in adults.
(18) Furthermore, an association of tiapride-corticoids was effective in treating post-anaesthetic spasm of the glottis.
(19) However EMLA is a useful anaesthetic for taking biopsies in this area and may be used as premedication for local infiltration.
(20) Seven or 14 days of treatment with the beta 2-adrenoceptor agonist clenbuterol, 0.3 mg kg-1, s.c., twice daily, increased the basal mean blood pressure in normotensive urethane-anaesthetized rats.
Topical
Definition:
(n.) Of or pertaining to a place; limited; logical application; as, a topical remedy; a topical claim or privilege.
(n.) Pertaining to, or consisting of, a topic or topics; according to topics.
(n.) Resembling a topic, or general maxim; hence, not demonstrative, but merely probable, as an argument.
Example Sentences:
(1) Furthermore, all of the sera from seven other patients with shock reactions following the topical application of chlorhexidine preparation also showed high RAST counts.
(2) Topical and systemic antibiotic therapy is common in dermatology, yet it is hard to find a rationale for a particular route in some diseases.
(3) Community involvement is a key element of the Primary Health Care (PHC) approach, and thus an essential topic on a course for managers of Primary Health Care programmes.
(4) The discussion on topics like post-schooling and rehabilitation of motorists has intensified the contacts between advocates of traffic law and traffic psychologists in the last years.
(5) Eighty micrograms of the topically active parasympatholytic drug ipratropium were applied intranasally four times daily in 20 adults with perennial rhinitis and severe watery rhinorrhoea in a double-blind controlled cross-over trial.
(6) Health information dissemination is severely complicated by the widespread stigma associated with digestive topics, manifested in the American public's general discomfort in communicating with others about digestive health.
(7) Female CD-1 mice were initiated with 200 nmol 7,12-dimethylbenz[a] anthracene and topically promoted three times weekly for 20 weeks with doses of 25, 50, 100, or 200 nmol mirex.
(8) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(9) "This will obviously be a sensitive topic for the US administration, but partners in the transatlantic alliance must be clear on common rules of engagement in times of conflict if we are to retain any moral standing in the world," Verhofstadt said.
(10) The decision of the editors to solicit a review for the Medical Progress series of this journal devoted to current concepts of the renal handling of salt and water is sound in that this important topic in kidney physiology has recently been the object of a number of new, exciting and, in some instances, quite unexpected insights into the mechanisms governing sodium excretion.
(11) The tetracaine component of TAC is superfluous for obtaining topical anesthesia of minor dermal lacerations of the face in children.
(12) I think we are still trying to understand all that and I think that fits under the broader topic of social licence and what bringing in automation to an area does to that region as a whole, which we don’t quite know yet.” Could carbon farming be the answer for a 'clapped-out' Australia?
(13) UPDATE II [Tues.] Two other items that may be of interest: first, Guardian editor-in-chief Alan Rusbridger was the guest for the full hour yesterday on Democracy Now, discussing the paper's role in reporting the NSA stories, and the video and transcript of the interview are here ; second, marking our collaboration on a series of articles about spying on Indians, the Hindu has a long interview with me on a variety of related topics, here .
(14) CNS excitation and seizures, manifestations of organochlorine intoxication, can occur following ingestion or inappropriate application of the 1 per cent topical formulation of lindane used to treat scabies and lice.
(15) A water based 5% benzoyl peroxide gel (Benzac W5) was compared with topical 1% clindamycin phosphate solution (Cleocin T) in the treatment of acne vulgaris using a randomized, investigator blind study design.
(16) In conclusion, this study indicates that topical CsA is capable of locally suppressing a strong T-cell-mediated immune response after an initial short-term systemic dose of CsA.
(17) Poly(ortho ester) bioerodible polymers are suitable materials for the topical administration of a wide variety of therapeutic agents; varying the nature and amounts of excipients physically incorporated into the polymer will vary the erosion rates from a few hours to many months.
(18) Future studies will need to carefully evaluate the vehicle used and the strength of topical CsA employed.
(19) The animal model of psoriasis was effectively treated by bimolane, both systemically and topically, and also by parenteral methotrexate and topical betamethasone valerate.
(20) Data were compared with those from a previous study with topical 1% minoxidil solution.