What's the difference between analogue and derivative?

Analogue


Definition:

  • (n.) That which is analogous to, or corresponds with, some other thing.
  • (n.) A word in one language corresponding with one in another; an analogous term; as, the Latin "pater" is the analogue of the English "father."
  • (n.) An organ which is equivalent in its functions to a different organ in another species or group, or even in the same group; as, the gill of a fish is the analogue of a lung in a quadruped, although the two are not of like structural relations.
  • (n.) A species in one genus or group having its characters parallel, one by one, with those of another group.
  • (n.) A species or genus in one country closely related to a species of the same genus, or a genus of the same group, in another: such species are often called representative species, and such genera, representative genera.

Example Sentences:

  • (1) The PSB dioxygenase system displayed a narrow substrate range: none of 18 sulphonated or non-sulphonated analogues of PSB showed significant substrate-dependent O2 uptake.
  • (2) A novel bicyclic prostaglandin analogue, (1S)-[1 alpha,2 alpha(Z),3 alpha,4 alpha]-7-[3-[(hexylthio)methyl]-7- oxabicyclo [2.2.1]hept-2-yl]-5-heptenoic acid ((-)-10), and its cogeners were found to be potent antagonists at the TxA2 receptor.
  • (3) A novel prostaglandin E2 analogue, CL 115347, can be administered transdermally on a long-term basis.
  • (4) The dog and the pig also have an endoperoxide-sensitive constrictor system activated by the 11,9-(epoxymethano) analogue of PGH2 and, of particular note, ICI 79939 and its 11-oxo analogue.
  • (5) During the chronic phase, pain was assessed using visual analogue scales at 8 AM and 4 PM daily.
  • (6) Analogues of [Orn6]-SP6-11 have been synthesized in which the Met11 residue is replaced by glutamate gamma-alkylesters.
  • (7) These results show that lipo-PGI2 at a very low dose would be beneficial as a treatment for relieving the clinical symptoms of chronic cerebral infarction and that lipid microspheres are a useful drug carrier for PGI2 analogue therapy.
  • (8) Cicaprost is an orally available analogue of PGI2 and has been shown to inhibit platelet aggregation in both in vitro and animal studies.
  • (9) The illumination of the F1-ATPase complexes with NAB-ADP or NAB-GDP leads to the covalent binding of one nucleotide analogue molecule to the enzyme and to the irreversible inactivation of F1-ATPase.
  • (10) Conversely, beta-L-homo analogues of fuconojirimycin can also be regarded as derivatives of deoxymannojirimycin.
  • (11) Thallium-201, a radiopharmaceutical that possesses many of the characteristics of potassium analogues, at present is receiving the greatest attention as a regional blood flow indicator.
  • (12) The administration of stable analogue of the leu-enkephalin did not alter the concentration of cortisole and aldosterone in the blood of white male rats whereas this concentration increased after administration of the parathormone.
  • (13) Assessments were made daily by patients, using visual analogue scales, of their pain levels at rest, at night and on activity, and of the limitation of their activity.
  • (14) The antidiuretic action of a number of vasopressin analogues has been measured in the rat and man in water diuresis.
  • (15) Second, interconversion of adenine nucleotides to guanine nucleotides, is curtailed by the inhibition of IMP dehydrogenase by these same IMP analogues.
  • (16) Adenylate cyclase activation by GTP non-hydrolyzable analogues was greatly decreased in immune, as compared to preimmune, antibody-treated membranes, whereas the enzyme basal activity was unaffected by both types of antibodies.
  • (17) This 50% inhibition varied from 70 pmole to 200 nmole using a series of NNK analogues, depending on the integrity of the POB moiety.
  • (18) In this work we have examined the binding characteristics of luciferin, luciferin analogues, and competitive inhibitors of the luciferin-luciferase reaction.
  • (19) A low-protein, low-phosphorus diet supplemented with essential amino acids and keto analogues was given to 12 rats, starting from the 90th day after subtotal nephrectomy.
  • (20) GTP and its analogues decrease the requirement of the reaction for Ca2+ and also increase its activity at saturating Ca2+.

Derivative


Definition:

  • (a.) Obtained by derivation; derived; not radical, original, or fundamental; originating, deduced, or formed from something else; secondary; as, a derivative conveyance; a derivative word.
  • (n.) That which is derived; anything obtained or deduced from another.
  • (n.) A word formed from another word, by a prefix or suffix, an internal modification, or some other change; a word which takes its origin from a root.
  • (n.) A chord, not fundamental, but obtained from another by inversion; or, vice versa, a ground tone or root implied in its harmonics in an actual chord.
  • (n.) An agent which is adapted to produce a derivation (in the medical sense).
  • (n.) A derived function; a function obtained from a given function by a certain algebraic process.
  • (n.) A substance so related to another substance by modification or partial substitution as to be regarded as derived from it; thus, the amido compounds are derivatives of ammonia, and the hydrocarbons are derivatives of methane, benzene, etc.

Example Sentences:

  • (1) The interaction of the antibody with both the bacterial and the tissue derived polysialic acids suggests that the conformational epitope critical for the interaction is formed by both classes of compounds.
  • (2) The vascular endothelium is capable of regulating tissue perfusion by the release of endothelium-derived relaxing factor to modulate vasomotor tone of the resistance vasculature.
  • (3) Leumorphin is a 29-amino-acid peptide derived from preproenkephalin B. Intracerebroventricular (i.c.v.)
  • (4) A full-length cDNA encoding porcine heart aconitase was derived from lambda gt10 recombinant clones and by amplification of the 5' end of the mRNA.
  • (5) In animal experiments pharmacological properties of the low molecular weight heparin derivative CY 216 were determined.
  • (6) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
  • (7) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
  • (8) PMNs could be primed for PMA-triggered oxidative burst by muramyl peptide molecules (MDP) and two of its adjuvant active nonpyrogenic derivatives.
  • (9) Recent studies have shown that an aberration in platelet-derived growth factor gene expression is unlikely to be a factor in proliferation of smooth-muscle cells.
  • (10) The macrophage-derived product, interleukin 1 (IL 1) is thought to play an important regulatory role in the proliferation of T lymphocytes; however, its mechanism of action is unknown.
  • (11) In the upper limb and facial forms of familial amyloidotic polyneuropathy first recorded in Swiss and Finns respectively, the differences in their patterns of neurological disease and ocular lesions could be the result of their amyloids deriving from proteins other than prealbumin.
  • (12) The antiproliferative activity of IFN was studied using the parental L cell line, a tk- derivative, and a tk- (tk+) subline into which the tk gene of herpes simplex virus was introduced.
  • (13) Bipolar derivations with the maximum PSE always included the locations with the maximum PSE obtained from a linked ears reference.
  • (14) Only those derivatives with a free amino group and net positive charge in the side chain were effective.
  • (15) Northern blot analysis with an 18-mer radiolabelled oligonucleotide, derived from an ALP specific cDNA clone, revealed a specific mRNA of about 700-800 nucleotides in HS-24 tumor cells.
  • (16) The mortality data were derived from the reports by Miyagi Prefectural Government.
  • (17) Ferrocene derivatives, in general, show a degree of versatility, coupling the electron-transfer reactions of many enzymes.
  • (18) The ADAM derivative of carnitine was separated from decomposition products of the reagent and related compounds such as amino acid derivatives on a silica gel column eluted with methanol-5% aqueous SDS-phosphoric acid (990:10:1).
  • (19) This doxorubicin derivative did not bind to Sepharose which was conjugated with cardiac actin.
  • (20) In the triploids, the 40 female chromosomes present (mouse, n = 20) were derived from a single diploid pronucleus formed after the extrusion of a first polar body, and following the monospermic fertilization of primary oocytes.